期刊
CHEMICAL COMMUNICATIONS
卷 52, 期 4, 页码 721-724出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5cc08328a
关键词
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资金
- National Natural Science Foundation of China [21272088, 21472059, 21402057, 81371684]
- Program for Academic Leader in Wuhan Municipality [201271130441]
A novel naphthalimide-based fluorescent probe employing a sulfonamide unit as a thiol-responsive group is reported. It is capable of efficiently distinguishing GSH from cysteine and homocysteine. Bioimaging shows that it has high selectivity in living cells and can visualize the level of GSH in lysosomes. It is worth mentioning that different groups on the imide unit can affect the selectivity and reaction dynamics of the probe towards thiols.
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