期刊
JOURNAL OF ORGANIC CHEMISTRY
卷 85, 期 8, 页码 5231-5244出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.9b03302
关键词
-
资金
- NSFC [21801221, 21861042, 21672184]
- Program for Changjiang Scholars and Innovative Research Team in University [IRT17R94]
- Program for Innovative Research Team (in Science and Technology) in University of Yunnan Province, Yunnan Province Government [2018FY001(016), 2018JS001, YNQR-QNRC-2018-005, 2019FD126]
- Yunnan University
- YunLing Scholar of Yunnan Province
Chiral phosphoric acid-catalyzed biomimetic asymmetric [4 + 2] cycloaddition of ortho-alkenyl naphthols/phenols and ortho-quinone methides (o-QMs) has been demonstrated to afford various important 2,3,4-trisubstituted chromans in high yields with excellent enantio- and diastereoselectivities (up to 99% yield, 99% ee, >20:1 dr). Notably, this methodology not only enabled access to the trans-cis chiral trisubstituted chromans from 1-alkenyl 2-naphthols but also is compatible with 2-alkenyl 1-naphthols and phenols to deliver trans-trans chiral trisubstituted chromans.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据