4.2 Article

High resolution multispectral endoscopy significantly improves the diagnostic accuracy of cervical intraepithelial lesions

期刊

出版社

WILEY
DOI: 10.1111/jog.14241

关键词

cervical intraepithelial neoplasia; colposcopy; diagnosis; endoscopy; optical imaging

资金

  1. National Natural Science Foundation of China [81771529]
  2. Shanghai Science and Technology Development Foundation [17441902500]
  3. Shanghai Hospital Development Center Foundation [16CR3089B]
  4. Fundamental Research Funds for the Central Universities [22120190241, 22120190214]
  5. Research Foundation of HwaMei Hospital, University of Chinese Academy of Sciences, China [2019HMKY11, 2020HMZD07]

向作者/读者索取更多资源

Colposcopy is a visual technique to examine the cervix and determine selection of sites for biopsies and eligibility for treatment. It's always been a critical part of identifying preinvasive and early invasive cervical carcinoma. Unfortunately, challenges exist with regards to the accuracy of traditional colposcopy. Hence, to fully exploit the benefit of increasing diagnostic sensitivity, there is a pressing need to improve the performance of colposcopy by applying novel innovations and techniques. In this case report, we used a recently developed, high-resolution multispectral endoscopy and evaluated its performance by comparing colposcopic image features (the vascular pattern, in particular, depending upon the improved optics and illumination) with histology results. High-resolution multispectral endoscopy makes it easier to distinguish the features of pathological vessels, so that it has a higher sensitivity and specificity to detect cervical lesions, especially in discriminating the vascular pattern using multispectral technology.

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