4.7 Article

Facile one-pot synthesis of carbon/calcium phosphate/Fe3O4 composite nanoparticles for simultaneous imaging and pH/NIR-responsive drug delivery

期刊

CHEMICAL COMMUNICATIONS
卷 52, 期 74, 页码 11068-11071

出版社

ROYAL SOC CHEMISTRY
DOI: 10.1039/c6cc05515j

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资金

  1. National Natural Science Foundation of China [21573040, 21301027, 21603029]
  2. Natural Science Foundation and Science and Technology Development Planning of Jilin Province [20140520088JH, 20150204086GX]
  3. Program for New Century Excellent Talents in University [NCET-13-0720]
  4. National Hi-Technology Research and Development Program (863 Program) [2013AA032204]
  5. Fundamental Research Funds for the Central Universities [2412016KJ007, 2412016KJ020]
  6. Jilin Provincial Research Foundation for Basic Research [20160519012JH]
  7. Jilin Provincial Key Laboratory of Micro-Nano Functional Materials (Northeast Normal University)

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A facile one-pot synthetic strategy was explored to synthesize carbon/calcium phosphate/Fe3O4 composite nanoparticles (carbon/CaP/Fe3O4 composite NPs). Taking advantage of the unique structure including mesoporous, small CaP and Fe3O4 subunits homogeneously distributed in a carbon matrix, carbon/CaP/Fe3O4 NPs integrate high drug loading, pH/NIR-sensitive, photothermal and magnetic properties into one nanoplatform for cancer theranostics.

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