4.7 Article

Fluorescent probes for the selective detection of chemical species inside mitochondria

期刊

CHEMICAL COMMUNICATIONS
卷 52, 期 6, 页码 1094-1119

出版社

ROYAL SOC CHEMISTRY
DOI: 10.1039/c5cc09248e

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资金

  1. National Natural Science Foundation of China [21302058]
  2. Research Fund for the Doctoral Program of Higher Education of China [20130076120006]
  3. Fundamental Research Funds for the Central Universities
  4. Science and Technology Project of Chongqing Municipal Education Commission [KJ1501129]
  5. Scientific Research Project of Chongqing University of Arts and Sciences [Y2014CH23]
  6. Opening Projects of Shanghai Key Laboratory of Chemical Biology
  7. Chongqing Key Laboratory of Environmental Materials and Remediation Technology [CEK1402]

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During the last few years, the preparation of novel fluorescent probes for the selective detection of chemical species inside mitochondria has attracted considerable attention because of their wide applications in chemistry, biology, and medical science. This feature article focuses on the recent advances in the design principles and recognition mechanisms of these kinds of fluorescent probes. In addition, their applications for the detection of reactive oxygen species (ROS), nitric oxide, reactive sulfur species (RSS), thioredoxin (Trx), metal ions, anions, etc. in the mitochondrion is discussed as well.

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