期刊
JOURNAL OF MEDICINAL CHEMISTRY
卷 63, 期 19, 页码 10652-10704出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.jmedchem.0c00345
关键词
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New drugs introduced to the market every year represent privileged structures for particular biological targets. These new chemical entities (NCEs) provide insight into molecular recognition while serving as leads for designing future new drugs. This annual review describes the most likely process-scale synthetic approaches to 39 new chemical entities approved for the first time globally in 2018.
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