期刊
CHEMICAL COMMUNICATIONS
卷 52, 期 7, 页码 1436-1438出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5cc08714g
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资金
- Engineering and Physical Sciences Research Council [EP/G028141/1, EP/K014668/1] Funding Source: researchfish
- EPSRC [EP/K014668/1, EP/G028141/1] Funding Source: UKRI
A simple, mild and general procedure for the hydration of nitriles to amides using copper as catalyst and promoted by N, N-diethyl-hydroxylamine is described. The reaction can be conducted in water at low temperature in short reaction times. This new procedure allows amides to be obtained from a wide range of substrates in excellent yields.
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