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John V. Dzimianski et al.
JOURNAL OF MOLECULAR BIOLOGY (2019)
Interferon-stimulated gene 15 modulates cell migration by interacting with Rac1 and contributes to lymph node metastasis of oral squamous cell carcinoma cells
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ISG15-Induced IL-10 Is a Novel Anti-Inflammatory Myeloid Axis Disrupted during Active Tuberculosis
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Cysteine-Reactive Free ISG15 Generates IL-1β-Producing CD8α+ Dendritic Cells at the Site of Infection
Anna Napolitano et al.
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ISG15 in antiviral immunity and beyond
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Subcellular Localization of Antigen in Keratinocytes Dictates Delivery of CD4+ T-cell Help for the CTL Response upon Therapeutic DNA Vaccination into the Skin
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USP18-a multifunctional component in the interferon response
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CD4+ T Cell Help Confers a Cytotoxic T Cell Effector Program Including Coinhibitory Receptor Downregulation and Increased Tissue Invasiveness
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Structural Insights into the Interaction of Coronavirus Papain-Like Proteases and Interferon-Stimulated Gene Product 15 from Different Species
Courtney M. Daczkowski et al.
JOURNAL OF MOLECULAR BIOLOGY (2017)
Extracellular ISG15 Signals Cytokine Secretion through the LFA-1 Integrin Receptor
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CD27 Agonism Plus PD-1 Blockade Recapitulates CD4+ T-cell Help in Therapeutic Anticancer Vaccination
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Human USP18 deficiency underlies type 1 interferonopathy leading to severe pseudo-TOR CH syndrome
Marije E. C. Meuwissen et al.
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ISG15 deficiency and increased viral resistance in humans but not mice
Scott D. Speer et al.
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Therapeutic cancer vaccines
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Ubiquitin-like Molecule ISG15 Acts as an Immune Adjuvant to Enhance Antigen-specific CD8 T-cell Tumor Immunity
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Selective inactivation of USP18 isopeptidase activity in vivo enhances ISG15 conjugation and viral resistance
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Identification and characterization of a novel ISG15-ubiquitin mixed chain and its role in regulating protein homeostasis
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ISG15 counteracts Listeria monocytogenes infection
Lilliana Radoshevich et al.
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Natural killer cells as helper cells in dendritic cell cancer vaccines
Maria Betina Pampena et al.
FRONTIERS IN IMMUNOLOGY (2015)
Human intracellular ISG15 prevents interferon-alpha/beta over-amplification and auto-inflammation
Xianqin Zhang et al.
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Interferon-Stimulated Genes: A Complex Web of Host Defenses
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ANNUAL REVIEW OF IMMUNOLOGY, VOL 32 (2014)
ISG15 Functions as an Interferon-Mediated Antiviral Effector Early in the Murine Norovirus Life Cycle
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Cross-talks between natural killer cells and distinct subsets of dencritic cells
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FRONTIERS IN IMMUNOLOGY (2014)
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
Michael I. Love et al.
GENOME BIOLOGY (2014)
Alarmin-induced cell migration
De Yang et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2013)
mHERC6 is the essential ISG15 E3 ligase in the murine system
Lars Ketscher et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2012)
Rational Design of DNA Vaccines for the Induction of Human Papillomavirus Type 16 E6-and E7-Specific Cytotoxic T-Cell Responses
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HUMAN GENE THERAPY (2012)
Mycobacterial Disease and Impaired IFN-γ Immunity in Humans with Inherited ISG15 Deficiency
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SCIENCE (2012)
Inducible Costimulator (ICOS) and ICOS Ligand Signaling Has Pivotal Roles in Skin Wound Healing via Cytokine Production
Shintaro Maeda et al.
AMERICAN JOURNAL OF PATHOLOGY (2011)
ISG15 Is Critical in the Control of Chikungunya Virus Infection Independent of UbE1L Mediated Conjugation
Scott W. Werneke et al.
PLOS PATHOGENS (2011)
The ISG15 Conjugation System Broadly Targets Newly Synthesized Proteins: Implications for the Antiviral Function of ISG15
Larissa A. Durfee et al.
MOLECULAR CELL (2010)
TREM and TREM-like receptors in inflammation and disease
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CURRENT OPINION IN IMMUNOLOGY (2009)
Interleukin-21 (IL-21)-mediated pathways in T cell-mediated disease
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TRENDS IN IMMUNOLOGY (2009)
Improved HIV-1 specific T-cell responses by short-interval DNA tattooing as compared to intramuscular immunization in non-human primates
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The effects of IL-20 subfamily cytokines on reconstituted human epidermis suggest potential roles in cutaneous innate defense and pathogenic adaptive immunity in psoriasis
Susan M. Sa et al.
JOURNAL OF IMMUNOLOGY (2007)
UBP43 is a novel regulator of interferon signaling independent of its ISG15 isopeptidase activity
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Homing and function of human skin γδ T cells and NK cells:: Relevance for tumor surveillance
Lisa M. Ebert et al.
JOURNAL OF IMMUNOLOGY (2006)
Herc5, an interferon-induced HECT E3 enzyme, is required for conjugation of ISG15 in human cells
A Dastur et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
ISG15, an interferon-stimulated ubiquitin-like protein, is not essential for STAT1 signaling and responses against vesicular stomatitis and lymphocytic choriomeningitis virus
A Osiak et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Crystal structure of the interferon-induced ubiquitin-like protein ISG15
J Narasimhan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
DC-NK cell cross talk as a novel CD4+ T-cell-independent pathway for antitumor CTL induction
C Adam et al.
BLOOD (2005)
Interferon-inducible ubiquitin E2, Ubc8, is a conjugating enzyme for protein ISGylation
KI Kim et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
The UbcH8 ubiquitin E2 enzyme is also the E2 enzyme for ISG15, an IFN-α/β-induced ubiquitin-like protein
C Zhao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Identification of a ubiquitin family protein as a novel neutrophil chemotactic factor
M Owhashi et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
Activation of natural killer T cells by α-galactosylceramide rapidly induces the full maturation of dendritic cells in vivo and thereby acts as an adjuvant for combined CD4 and CD8 T cell immunity to a coadministered protein
S Fujii et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
Proteasomes modulate conjugation to the ubiquitin-like protein, ISG15
MJ Liu et al.
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Natural killer and dendritic cell contact in lesional atopic dermatitis skin -: Malassezia-influenced cell interaction
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JOURNAL OF INVESTIGATIVE DERMATOLOGY (2002)
UBP43 (USP18) specifically removes ISG15 from conjugated proteins
MP Malakhov et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Influenza B virus NS1 protein inhibits conjugation of the interferon (IFN)-induced ubiquitin-like ISG15 protein
WM Yuan et al.
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