期刊
CHEMICAL COMMUNICATIONS
卷 52, 期 63, 页码 9801-9804出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c6cc02387h
关键词
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A novel vacuum stable proton sponge, 4-maleicanhydridoproton sponge (MAPS), was prepared and applied as the matrix in Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging (MALDI-MSI) of an aggressive brain tumor tissue (glioblastoma multiforme). Ionic maps of lactate, 2-hydroxyglutarate and chloride anions (m/z 89, 147, 35, respectively) were obtained using a routine MALDI ToF mass spectrometer.
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