期刊
CHEMICAL COMMUNICATIONS
卷 52, 期 41, 页码 6833-6836出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c6cc03138b
关键词
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资金
- National Basic Research Program of China (973 Program) [2012CB720600, 2012CB720603]
- National Science Foundation of China [21432008, 91413109, 21372182]
We present here a novel and efficient method for 5mC detection using a DNA strand exchange reaction (SER) strategy. This enzyme-free method needs no pre-treatment of target DNAs and can be adapted to most of the target duplexes under physiological conditions. The high sequence selectivity of this method can distinguish 5mC from normal cytosine in an accurate manner.
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