期刊
JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE
卷 57, 期 11, 页码 4228-4235出版社
SPRINGER INDIA
DOI: 10.1007/s13197-020-04461-y
关键词
Antibacterial activity; Artepillin C; Baccharis dracunculifolia; Caffeoyl-quinic acids; Propolis
资金
- FAPESP (Fundacao de Amparo a Pesquisa do Estado de Sao Paulo) [2013/21813-0]
- CAPES (Coordenacao de Aperfeicoamento do Pessoal de Nivel Superior)
Extracts of a sample of brown propolis produced in the district of Itapara (Southern Brazil) were obtained with solvents with increasing polarity. The extracts were analyzed by RPHPLC-DAD-ESI-MS/MS and evaluated toward activity against Mycoplasma bovis, M. gallisepticum, M. genitalium, M. hominis, M. hyorinis, M. penetrans and M. pneumonieae. Typical components of alecrim-do-campo propolis (e.g. prenylated phenylpropanoids and caffeoyl-quinic acids) were characterized in the analyzed extraccts, in addition to several flavonols. Less polar extracts showed higher anti-mycoplasma activity (MIC value commonly 3.9 mu g/mL) than alcoholic and aqueous extracts (MIC value often 7.8-250 mu g/mL). The results indicate that Itapara propolis is a promising source for the development of therapeutic drugs.
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