期刊
JOURNAL OF EXPERIMENTAL MEDICINE
卷 217, 期 4, 页码 -出版社
ROCKEFELLER UNIV PRESS
DOI: 10.1084/jem.20191865
关键词
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资金
- National Institutes of Health [NS106668, NS102721]
- Cure Alzheimer's Fund
- Alzheimer's Association
- Alzheimer's Drug Discovery Foundation
- Samuel I. Newhouse Foundation
- Rudin Family Foundation
Plasminogen and its active form, plasmin, have diverse functions related to the inflammatory response in mammals. Due to these roles in inflammation, plasminogen has been implicated in the progression of a wide range of diseases with an inflammatory component. In this review, we discuss the functions of plasminogen in inflammatory regulation and how this system plays a role in the pathogenesis of diseases spanning organ systems throughout the body.
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