期刊
CHEMICAL COMMUNICATIONS
卷 52, 期 70, 页码 10652-10655出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c6cc04538c
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资金
- National Natural Science Foundation of China [21271066, 21171051, U1204516]
- Program for Science & Technology Innovation Talents in Universities of Henan Province [13HASTIT011]
- Key Young Teachers Project of Henan Province [2012GGJS-065]
Hollow silica nanospheres coated with biocompatible and pH-sensitive inorganic insoluble calcium salts including calcium carbonate and hydroxyapatite have been successfully prepared. The results indicate that the nanospheres can efficiently load doxorubicin and release it in a pH-responsive and sustained manner, and improve the treatment efficacy significantly.
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