期刊
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
卷 68, 期 14, 页码 4187-4195出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.jafc.9b07481
关键词
human milk; infant formula; lipolysis; in vitro digestion; medium-chain fatty acids
资金
- National Natural Science Foundation of China [31701558]
- Postgraduate Research & Practice Innovation Program of Jiangsu Province [KYCX19_1814]
- Overseas Expertise Introduction Project for Discipline Innovation (111 Project) [B90719028]
Medium-chain triacylglycerol (MCT) is widely used in infant formulas (IFs) to provide medium-chain fatty acids (MCFAs) for infants with special fat absorption requirements. However, MCFAs naturally present in human milk are medium-and long-chain triacylglycerols (MLCTs). This study investigated the effect of triacylglycerol containing MCFAs (MLCT vs MCT) on lipolysis by comparison of human milk and IFs containing 0, 20, 30, and 55% of MCT (IF 1 to IF 4) using an in vitro digestion model. Rabbit gastric lipase showed an extent of digestion within the expected range, and was selected as the alternative to human gastric lipase. All IFs showed a lower lipolysis degree compared with human milk. There was no significant difference (p = 0.175) among IFs supplemented with MCT at the end of intestinal digestion. In addition, the digestion of IFs with different MCT contents led to different free fatty acid profiles, which may have health effects on infants.
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