期刊
JAPANESE JOURNAL OF APPLIED PHYSICS
卷 59, 期 -, 页码 -出版社
IOP PUBLISHING LTD
DOI: 10.35848/1347-4065/ab83dc
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资金
- JSPS KAKENHI [19H04436, 17K11529]
- Termo Foundation for Life Sciences and Arts
- JSPS Core-to-Core Program
- Institute for Global Prominent Research at Chiba University
- Tenure Track program at Chiba University
- Grants-in-Aid for Scientific Research [17K11529, 19H04436] Funding Source: KAKEN
Contrast-enhanced ultrasound imaging using acoustic radiation force, called contrast-enhanced active Doppler ultrasound (CEADUS) imaging, has been proposed for visualizing lymph channels filled with stationary fluid. Based on optical observations and acoustical evaluation, the behaviour of bubbles in a simulated channel during ultrasound exposure was investigated under four conditions for negative peak sound pressure (P-np), at centre frequency of ultrasound and pulse repetition frequency of 15 MHz and 1 kHz, respectively. There was good correlation between the time changes of mean translational velocity for optical evaluation (V-OPT) and acoustical evaluation (V-US). In addition, the maxima of V-OPT and V-US were correlated (R = 0.665) and showed a similar trend proportional to the square of Pnp. These results strongly suggest that the acoustically-evaluated bubble translation has information equal to optically-evaluated one, meaning that the simultaneous observation system is useful to understand the bubble behaviours under CEADUS imaging. (C) 2020 The Japan Society of Applied Physics
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