期刊
INTERNATIONAL REVIEWS OF IMMUNOLOGY
卷 39, 期 6, 页码 292-298出版社
TAYLOR & FRANCIS INC
DOI: 10.1080/08830185.2020.1768251
关键词
Antigen presentation; interleukin; macrophage polarization; reactive oxygen species; TNF-alpha
类别
资金
- Outstanding Clinical Discipline Project of Shanghai Pudong [PWYgy-2018-08]
- Program for Medical Key Departments of Shanghai [ZK2019A10]
Reactive oxygen species (ROS) is a kind of single electron reduction product of oxygen in vivo. Because they contain unpaired electrons, ROS has high chemical reactivity. Various researches of ROS are focused on DNA damage, cell apoptosis, oxidative stress. Actually, ROS is also closed related to immune regulation. Based on this, we review the research in immune regulated ROS production, regulation of ROS on inflammatory factors and inflammatory response, antigen presentation and macrophage polarization for better understanding of its role.
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