4.2 Article

Lymphomatosis cerebri with cauda equina lymphoma

期刊

INTERNATIONAL JOURNAL OF NEUROSCIENCE
卷 131, 期 9, 页码 902-908

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TAYLOR & FRANCIS LTD
DOI: 10.1080/00207454.2020.1759593

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primary central nervous system lymphoma; lymphomatosis cerebri; cauda equina; CSF cytology; flow cytometry

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This case report presents a rare case of LC with cauda equina involvement, emphasizing the importance of employing a multimodal strategy in diagnosing PCNSL, including multimodal magnetic resonance, cerebral spinal fluid cytology, flow cytometry and fluorodeoxyglucose positron emission tomography/computed tomography.
Purpose/aim: Lymphomatosis cerebri (LC) and cauda equina lymphoma are both rare forms of primary central nervous system lymphoma (PCNSL). LC is characterized by diffuse bilateral non-enhancing (or partially enhancing) inltrative lesions without mass effect, which can be easily confused with other forms of leukoencephalopathy and, thus, lead to delays in diagnosis. Case report: For the first time, a case of LC concomitant with cauda equina involvement confirmed by brain stereotactic biopsy is presented. Conclusions: This case highlights the necessity of using a multimodal strategy in diagnosing PCNSL, including multimodal magnetic resonance, cerebral spinal fluid cytology, flow cytometry and fluorodeoxyglucose positron emission tomography/computed tomography.

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