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Itsaso Cabezon et al.
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Daniela Luz et al.
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Nga Bien-Ly et al.
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Jens Niewoehner et al.
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Brian Spencer et al.
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Darrell Sleep et al.
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Y. Joy Yu et al.
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N. Joan Abbott et al.
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Tracey A. Rouault et al.
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Wolfgang Hoyer et al.
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Andreas Jonsson et al.
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BT Hawkins et al.
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Mechanism for multiple ligand recognition by the human transferrin receptor
AM Giannetti et al.
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Structure, specificity, and mode of interaction for bacterial albumin-binding modules
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