期刊
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
卷 96, 期 -, 页码 459-460出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.ijid.2020.05.071
关键词
COVID-19; SARS-CoV-2; Coronavirus; S-Protein; D614G
资金
- Kuwait Foundation for the Advancement of Sciences
The increasing number of deaths due to the COVID-19 pandemic has raised serious global concerns. Increased testing capacity and ample intensive care availability could explain lower mortality in some countries compared to others. Nevertheless, it is also plausible that the SARS-CoV-2 mutations giving rise to different phylogenetic clades are responsible for the apparent death rate disparities around the world. Current research literature linking the genetic make-up of SARS-CoV-2 with fatalities is lacking. Here, we suggest that this disparity in fatality rates may be attributed to SARS-CoV-2 evolving mutations and urge the international community to begin addressing the phylogenetic Glade classification of SARS-CoV-2 in relation to clinical outcomes. (C) 2020 The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.
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