相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Monoclonal antibodies against metzincin targets
Salvatore Santamaria et al.
BRITISH JOURNAL OF PHARMACOLOGY (2019)
Emerging therapeutic agents in osteoarthritis
Maria Jose Alcaraz et al.
BIOCHEMICAL PHARMACOLOGY (2019)
ADAMTS5 deficiency in mice does not affect cardiac function
Bianca Hemmeryckx et al.
CELL BIOLOGY INTERNATIONAL (2019)
Glycoproteomic Analysis of the Aortic Extracellular Matrix in Marfan Patients
Xiaoke Yin et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2019)
Exosites in Hypervariable Loops of ADAMTS Spacer Domains control Substrate Recognition and Proteolysis
Salvatore Santamaria et al.
SCIENTIFIC REPORTS (2019)
Adamts5-/- Mice Exhibit Altered Aggrecan Proteolytic Profiles That Correlate With Ascending Aortic Anomalies
Loren E. Dupuis et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2019)
Matrix-degrading protease ADAMTS-5 cleaves inter-?-inhibitor and releases active heavy chain 2 in synovial fluids from arthritic patients
Carsten Scavenius et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2019)
Crystal structure and substrate-induced activation of ADAMTS13
Anastasis Petri et al.
NATURE COMMUNICATIONS (2019)
Role of ADAMTS-5 in Aortic Dilatation and Extracellular Matrix Remodeling
Marika Fava et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2018)
ADAMTS-5 INHIBITION WITH THE POTENT AND HIGHLY SELECTIVE INHIBITOR GLPG1972 RESULTS IN STRONG DISEASE-MODIFYING OA DRUG EFFECTS IN THE RAT MENISCECTOMY MODEL
P. Clement-Lacroix et al.
OSTEOARTHRITIS AND CARTILAGE (2018)
PHARMACOKINETIC AND PHARMACODYNAMIC MODELLING OF THE NOVEL ANTI-ADAMTS-5 NANOBODY M6495 USING THE NEO-EPITOPE ARGS AS A BIOMARKER
J. Pereira et al.
OSTEOARTHRITIS AND CARTILAGE (2018)
IN VITRO CHARACTERIZATION OF THE ADAMTS-5 SPECIFIC NANOBODY® M6495
D. Werkmann et al.
OSTEOARTHRITIS AND CARTILAGE (2018)
STRUCTURAL AND SYMPTOMATIC BENEFIT OF A HALF-LIVE EXTENDED, SYSTEMICALLY APPLIED ANTI-ADAMTS-5 INHIBITOR (M6495)
C. Brenneis et al.
OSTEOARTHRITIS AND CARTILAGE (2018)
ADAMTS-5 INHIBITOR GLPG1972, A POTENTIAL NEW TREATMENT IN OSTEOARTHRITIS, SHOWS FAVORABLE SAFETY, PHARMACOKINETICS AND PHARMACODYNAMICS IN HEALTHY SUBJECTS
E. M. van der Aar et al.
OSTEOARTHRITIS AND CARTILAGE (2018)
Functional role of ADAMTS5 in adiposity and metabolic health
Dries Bauters et al.
PLOS ONE (2018)
The matrix proteins aggrecan and fibulin-1 play a key role in determining aortic stiffness
Yasmin et al.
SCIENTIFIC REPORTS (2018)
Recombinant TSR1 of ADAMTS5 Suppresses Melanoma Growth in Mice via an Anti-angiogenic Mechanism
Bhuvanasundar Renganathan et al.
CANCERS (2018)
Extracellular Matrix Proteomics Reveals Interplay of Aggrecan and Aggrecanases in Vascular Remodeling of Stented Coronary Arteries
Gonca Suna et al.
CIRCULATION (2018)
Massive aggrecan and versican accumulation in thoracic aortic aneurysm and dissection
Frank S. Cikach et al.
JCI INSIGHT (2018)
An aggrecan fragment drives osteoarthritis pain through Toll-like receptor 2
Rachel E. Miller et al.
JCI INSIGHT (2018)
Gene expression profiling of acute type A aortic dissection combined with in vitro assessment
Naoyuki Kimura et al.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY (2017)
Versican-Derived Matrikines Regulate Batf3-Dendritic Cell Differentiation and Promote T Cell Infiltration in Colorectal Cancer
Chelsea Hope et al.
JOURNAL OF IMMUNOLOGY (2017)
Development of a monoclonal anti-ADAMTS-5 antibody that specifically blocks the interaction with LRP1
Salvatore Santamaria et al.
MABS (2017)
Nitric oxide mediates aortic disease in mice deficient in the metalloprotease Adamts1 and in a mouse model of Marfan syndrome
Jorge Oller et al.
NATURE MEDICINE (2017)
GLPG1972: A POTENT, SELECTIVE, ORALLY AVAILABLE ADAMTS-5 INHIBITOR FOR THE TREATMENT OF OA
P. Clement-Lacroix et al.
OSTEOARTHRITIS AND CARTILAGE (2017)
ADAMTS and ADAM metalloproteinases in osteoarthritis-looking beyond the 'usual suspects'
C. -Y. Yang et al.
OSTEOARTHRITIS AND CARTILAGE (2017)
Stromal Versican Regulates Tumor Growth by Promoting Angiogenesis
Keiichi Asano et al.
SCIENTIFIC REPORTS (2017)
Inhibition of Shedding of Low-Density Lipoprotein Receptor-Related Protein 1 Reverses Cartilage Matrix Degradation in Osteoarthritis
Kazuhiro Yamamoto et al.
ARTHRITIS & RHEUMATOLOGY (2017)
Loss of ADAMTS5 enhances brown adipose tissue mass and promotes browning of white adipose tissue via CREB signaling
Dries Bauters et al.
MOLECULAR METABOLISM (2017)
High expression of ADAMTS5 is a potent marker for lymphatic invasion and lymph node metastasis in colorectal cancer
Naotsugu Haraguchi et al.
MOLECULAR AND CLINICAL ONCOLOGY (2017)
Effect of inhibiting MMP13 and ADAMTS5 by intra-articular injection of small interfering RNA in a surgically induced osteoarthritis model of mice
Hiroko Hoshi et al.
CELL AND TISSUE RESEARCH (2017)
Effects of exercise therapy on walking ability in individuals with knee osteoarthritis: a systematic review and meta-analysis of randomised controlled trials
Ryo Tanaka et al.
CLINICAL REHABILITATION (2016)
A Disintegrin and Metalloproteinase with Thrombospondin Motifs-5 (ADAMTS-5) Forms Catalytically Active Oligomers
Hansen J. Kosasih et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Immunoregulatory roles of versican proteolysis in the myeloma microenvironment
Chelsea Hope et al.
BLOOD (2016)
ADAMTS5 deficiency protects against non-alcoholic steatohepatitis in obesity
Dries Bauters et al.
LIVER INTERNATIONAL (2016)
Therapeutic effects of an anti-ADAMTS-5 antibody on joint damage and mechanical allodynia in a murine model of osteoarthritis
R. E. Miller et al.
OSTEOARTHRITIS AND CARTILAGE (2016)
Loss of ADAMTS4 reduces high fat diet-induced atherosclerosis and enhances plaque stability in ApoE-/- mice
Saran Kumar et al.
SCIENTIFIC REPORTS (2016)
ADAMTS5 Is a Critical Regulator of Virus-Specific T Cell Immunity
Meagan McMahon et al.
PLOS BIOLOGY (2016)
Antibody-based exosite inhibitors of ADAMTS-5 (aggrecanase-2)
Salvatore Santamaria et al.
BIOCHEMICAL JOURNAL (2015)
The Cerebral Cavernous Malformation Pathway Controls Cardiac Development via Regulation of Endocardial MEKK3 Signaling and KLF Expression
Zinan Zhou et al.
DEVELOPMENTAL CELL (2015)
Deletion of ADAMTS5 does not affect aggrecan or versican degradation but promotes glucose uptake and proteoglycan synthesis in murine adipose derived stromal cells
Daniel J. Gorski et al.
MATRIX BIOLOGY (2015)
Moving targets: Emerging roles for MMPs in cancer progression and metastasis
Gemma Shay et al.
MATRIX BIOLOGY (2015)
Translational development of an ADAMTS-5 antibody for osteoarthritis disease modification
J. Larkin et al.
OSTEOARTHRITIS AND CARTILAGE (2015)
Lost expression of ADAMTS5 protein associates with progression and poor prognosis of hepatocellular carcinoma
Chongyi Li et al.
DRUG DESIGN DEVELOPMENT AND THERAPY (2015)
Genetic susceptibility of lumbar degenerative disc disease in young Indian adults
S. Rajasekaran et al.
EUROPEAN SPINE JOURNAL (2015)
Determinants of Versican-V1 Proteoglycan Processing by the Metalloproteinase ADAMTS5
Simon J. Foulcer et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
THE HIGHS AND LOWS OF TRANSLATIONAL DRUG DEVELOPMENT: ANTIBODY-MEDIATED INHIBITION OF ADAMTS-5 FOR OSTEOARTHRITIS DISEASE MODIFICATION
J. Larkin et al.
OSTEOARTHRITIS AND CARTILAGE (2014)
ADAMTS4 and ADAMTS5 Knockout Mice Are Protected from Versican but Not Aggrecan or Brevican Proteolysis during Spinal Cord Injury
Kadir Demircan et al.
BIOMED RESEARCH INTERNATIONAL (2014)
Expression and distribution of aggrecanases in human larynx: ADAMTS-5/aggrecanase-2 is the main aggrecanase in laryngeal carcinoma
S. Filou et al.
BIOCHIMIE (2013)
LRP-1-mediated endocytosis regulates extracellular activity of ADAMTS-5 in articular cartilage
Kazuhiro Yamamoto et al.
FASEB JOURNAL (2013)
Protective effect of lentivirus-mediated siRNA targeting ADAMTS-5 on cartilage degradation in a rat model of osteoarthritis
Xiangyu Chu et al.
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2013)
Versican Processing by a Disintegrin-like and Metalloproteinase Domain with Thrombospondin-1 Repeats Proteinases-5 and-15 Facilitates Myoblast Fusion
Nicole Stupka et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Biosynthesis and Expression of a Disintegrin-like and Metalloproteinase Domain with Thrombospondin-1 Repeats-15 A NOVEL VERSICAN-CLEAVING PROTEOGLYCANASE
Carolyn M. Dancevic et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Insufficient versican cleavage and Smad2 phosphorylation results in bicuspid aortic and pulmonary valves
Loren E. Dupuis et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2013)
ADAMTS5 is required for biomechanically-stimulated healing of murine tendinopathy
Rebecca Bell et al.
JOURNAL OF ORTHOPAEDIC RESEARCH (2013)
ADAMTS1, ADAMTS5, ADAMTS9 and aggrecanase-generated proteoglycan fragments are induced following spinal cord injury in mouse
Kadir Demircan et al.
NEUROSCIENCE LETTERS (2013)
Targeting of ADAMTS5's ancillary domain with the recombinant mAb CRB0017 ameliorates disease progression in a spontaneous murine model of osteoarthritis
R. Chiusaroli et al.
OSTEOARTHRITIS AND CARTILAGE (2013)
ADAMTS5 Functions as an Anti-Angiogenic and Anti-Tumorigenic Protein Independent of Its Proteoglycanase Activity
Saran Kumar et al.
AMERICAN JOURNAL OF PATHOLOGY (2012)
Novel Role of ADAMTS-5 Protein in Proteoglycan Turnover and Lipoprotein Retention in Atherosclerosis
Athanasios Didangelos et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Murine tendon function is adversely affected by aggrecan accumulation due to the knockout of ADAMTS5
Vincent M. Wang et al.
JOURNAL OF ORTHOPAEDIC RESEARCH (2012)
Regulated Proteolytic Processing of Reelin through Interplay of Tissue Plasminogen Activator (tPA), ADAMTS-4, ADAMTS-5, and Their Modulators
Dimitrije Krstic et al.
PLOS ONE (2012)
Epigenomic Analysis of Aberrantly Methylated Genes in Colorectal Cancer Identifies Genes Commonly Affected by Epigenetic Alterations
Young-Ho Kim et al.
ANNALS OF SURGICAL ONCOLOGY (2011)
Altered versican cleavage in ADAMTS5 deficient mice; A novel etiology of myxomatous valve disease
Loren E. Dupuis et al.
DEVELOPMENTAL BIOLOGY (2011)
Pericellular Versican Regulates the Fibroblast-Myofibroblast Transition A ROLE FOR ADAMTS5 PROTEASE-MEDIATED PROTEOLYSIS
Noriko Hattori et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Adamts5 Deletion Blocks Murine Dermal Repair through CD44-mediated Aggrecan Accumulation and Modulation of Transforming Growth Factor β1 (TGFβ1) Signaling
Jennifer Velasco et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Knockout of ADAMTS5 Does Not Eliminate Cartilage Aggrecanase Activity but Abrogates Joint Fibrosis and Promotes Cartilage Aggrecan Deposition in Murine Osteoarthritis Models
Jun Li et al.
JOURNAL OF ORTHOPAEDIC RESEARCH (2011)
The role of the cartilage matrix in osteoarthritis
Dick Heinegard et al.
NATURE REVIEWS RHEUMATOLOGY (2011)
Expression Profiles and Clinical Correlations of Degradome Components in the Tumor Microenvironment of Head and Neck Squamous Cell Carcinoma
Angela Stokes et al.
CLINICAL CANCER RESEARCH (2010)
Epidemiology of Osteoarthritis
Yuqing Zhang et al.
CLINICS IN GERIATRIC MEDICINE (2010)
Versican expression is associated with tumor-infiltrating CD8-positive T cells and infiltration depth in cervical cancer
Arko Gorter et al.
MODERN PATHOLOGY (2010)
Leptin plays a catabolic role on articular cartilage
Jia-peng Bao et al.
MOLECULAR BIOLOGY REPORTS (2010)
ADAMTS-5 deficient mice do not develop mechanical allodynia associated with osteoarthritis following medial meniscal destabilization
A. M. Malfait et al.
OSTEOARTHRITIS AND CARTILAGE (2010)
Ligation of TLR2 by Versican: A Link Between Inflammation and Metastasis
Wei Wang et al.
ARCHIVES OF MEDICAL RESEARCH (2009)
ADAMTS Metalloproteases Generate Active Versican Fragments that Regulate Interdigital Web Regression
Daniel R. McCulloch et al.
DEVELOPMENTAL CELL (2009)
Tissue Inhibitor of Metalloproteinase 3 Deficiency Causes Hepatic Steatosis and Adipose Tissue Inflammation in Mice
Rossella Menghini et al.
GASTROENTEROLOGY (2009)
Adamts5, the gene encoding a proteoglycan-degrading metalloprotease, is expressed by specific cell lineages during mouse embryonic development and in adult tissues
Daniel R. McCulloch et al.
GENE EXPRESSION PATTERNS (2009)
INCREASED mRNA EXPRESSION OF ADAMTS METALLOPROTEINASES IN METASTATIC FOCI OF HEAD AND NECK CANCER
Kadir Demircan et al.
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK (2009)
Characterization of proADAMTS5 processing by proprotein convertases
Jean-Michel Longpre et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2009)
Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis
Sunhwa Kim et al.
NATURE (2009)
Single domain antibodies: promising experimental and therapeutic tools in infection and immunity
Janusz Wesolowski et al.
MEDICAL MICROBIOLOGY AND IMMUNOLOGY (2009)
ADAMTS5-/- mice have less subchondral bone changes after induction of osteoarthritis through surgical instability: implications for a link between cartilage and subchondral bone changes
S. M. Botter et al.
OSTEOARTHRITIS AND CARTILAGE (2009)
Crystal structures of the noncatalytic domains of ADAMTS13 reveal multiple discontinuous exosites for von Willebrand factor
Masashi Akiyama et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Effect of small interference RNA (siRNA) for ADAMTS5 on intervertebral disc degeneration in the rabbit anular needle-puncture model
Shoji Seki et al.
ARTHRITIS RESEARCH & THERAPY (2009)
Evidence of a novel aggrecan-degrading activity in cartilage - Studies of mice deficient in both ADAMTS-4 and ADAMTS-5
Fraser M. Rogerson et al.
ARTHRITIS AND RHEUMATISM (2008)
Characterization of metalloprotease cleavage products of human articular cartilage
Eugene Y. Zhen et al.
ARTHRITIS AND RHEUMATISM (2008)
ADAMTS-4 and-8 are inflammatory regulated enzymes expressed in macrophage-rich areas of human atherosclerotic plaques
Dick Wagsater et al.
ATHEROSCLEROSIS (2008)
The first but not the second thrombospondin type 1 repeat of ADAMTS5 functions as an angiogenesis inhibitor
Soheila Sharghi-Namini et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Multimodal signaling by the ADAMTSs (a disintegrin and metalloproteinase with thrombospondin motifs) promotes neurite extension
Michelle G. Hamel et al.
EXPERIMENTAL NEUROLOGY (2008)
BEHAB/brevican requires ADAMTS-mediated proteolytic cleavage to promote glioma invasion
Mariano Sebastian Viapiano et al.
JOURNAL OF NEURO-ONCOLOGY (2008)
Cartilage degradation is fully reversible in the presence of aggrecanase but not matrix metalloproteinase activity
Morten A. Karsdal et al.
ARTHRITIS RESEARCH & THERAPY (2008)
Functional differences of the catalytic and non-catalytic domains in human ADAMTS-4 and ADAMTS-5 in aggrecanolytic activity
Kazunari Fushimi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Estimates of the prevalence of arthritis and other rheumatic conditions in the United States
Charles G. Helmick et al.
ARTHRITIS AND RHEUMATISM (2008)
Expression of ADAMTS4 (aggrecanase-1) in human osteoarthritic cartilage
Satoko Naito et al.
PATHOLOGY INTERNATIONAL (2007)
Double-knockout of ADAMTS-4 and ADAMTS-5 in mice results in physiologically normal animals and prevents the progression of osteoarthritis
Manas K. Majumdar et al.
ARTHRITIS AND RHEUMATISM (2007)
Proteolytic activities of human ADAMTS-5 - Comparative studies with ADAMTS-4
Christi Gendron et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Blocking aggrecanase cleavage in the aggrecan interglobular domain abrogates cartilage erosion and promotes cartilage repair
Christopher B. Little et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
ADAMTS-5 deficiency does not block aggrecanolysis at preferred cleavage sites in the chondroitin sulfate-rich region of aggrecan
Charlotte J. East et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Versican proteolysis mediates myocardial. regression during outflow tract development
Christine B. Kern et al.
DEVELOPMENTAL DYNAMICS (2007)
Aggrecan degradation in human articular cartilage explants is mediated by both ADAMTS-4 and ADAMTS-5
Ruo-Hua Song et al.
ARTHRITIS AND RHEUMATISM (2007)
Crucial role of macrophages in matrix metalloproteinase-mediated cartilage destruction during experimental osteoarthritis - Involvement of matrix metalloproteinase 3
Arjen B. Blom et al.
ARTHRITIS AND RHEUMATISM (2007)
Liver heparan sulfate proteoglycans mediate clearance of triglyceride-rich lipoproteins independently of LDL receptor family members
Jennifer M. MacArthur et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Expression of aggrecan(ases) during murine preadipocyte differentiation and adipose tissue development
Gabor Voros et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2006)
The cleavage of biglycan by aggrecanases
L. I. Melching et al.
OSTEOARTHRITIS AND CARTILAGE (2006)
Glycosaminoglycan-binding properties and aggrecanase activities of truncated ADAMTSs: Comparative analyses with ADAMTS-5,-9,-16 and-18
WL Zeng et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2006)
Matrix-degrading proteases ADAMTS4 and ADAMTS5 (disintegrins and metalloproteinases with thrombospondin motifs 4 and 5) are expressed in human glioblastomas
J Held-Feindt et al.
INTERNATIONAL JOURNAL OF CANCER (2006)
Expression of versican and ADAMTS1, 4, and 5 during bone development in the rat mandible and hind limb
M Nakamura et al.
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2005)
Fibulin-1 acts as a cofactor for the matrix metalloprotease ADAMTS-1
NV Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
被撤回的出版物: Lack of CpG island methylator phenotype defines a clinical subtype of T-cell acute lymphoblastic leukemia associated with good prognosis (Retracted article. See vol. 31, pg. 979, 2013)
J Roman-Gomez et al.
JOURNAL OF CLINICAL ONCOLOGY (2005)
Human glioblastomas overexpress ADAMTS-5 that degrades brevican
M Nakada et al.
ACTA NEUROPATHOLOGICA (2005)
Analysis of intimal proteoglycans in atherosclerosis-prone and atherosclerosis-resistant human arteries by mass spectrometry
P Talusan et al.
MOLECULAR & CELLULAR PROTEOMICS (2005)
The expression and regulation of ADAMTS-1, -4, -5, -9, and -15, and TIMP-3 by TGFβ1 in prostate cells:: Relevance to the accumulation of versican
NA Cross et al.
PROSTATE (2005)
ADAMTS-1-knockout mice do not exhibit abnormalities in aggrecan turnover in vitro or in vivo
CB Little et al.
ARTHRITIS AND RHEUMATISM (2005)
Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis
SS Glasson et al.
NATURE (2005)
ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro
H Stanton et al.
NATURE (2005)
The hyalectan degrading ADAMTS-1 enzyme is expressed by osteoblasts and up-regulated at regions of new bone formation
T Lind et al.
BONE (2005)
Role of ADAMTS-1 in atherosclerosis - Remodeling of carotid artery, immunohistochemistry, and proteolysis of versican
AC Jonnsson-Rylander et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2005)
α2-Macroglobulin is a novel substrate for ADAMTS-4 and ADAMTS-5 and represents an endogenous inhibitor of these enzymes
MD Tortorella et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Dysregulated expression of adamalysin-thrombospondin genes in human breast carcinoma
S Porter et al.
CLINICAL CANCER RESEARCH (2004)
Altered proteolytic activities of ADAMTS-4 expressed by C-terminal processing
M Kashiwagi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Regeneration beyond the glial scar
J Silver et al.
NATURE REVIEWS NEUROSCIENCE (2004)
Characterization of and osteoarthritis susceptibility in ADAMTS-4-knockout mice
SS Glasson et al.
ARTHRITIS AND RHEUMATISM (2004)
ADAMTS-8 exhibits aggrecanase activity and is expressed in human articular cartilage
LA Collins-Racie et al.
MATRIX BIOLOGY (2004)
Matrix proteoglycans are markedly affected in advanced laryngeal squamous cell carcinoma
SS Skandalis et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2004)
Expression profiling of metalloproteinases and their inhibitors in cartilage
L Kevorkian et al.
ARTHRITIS AND RHEUMATISM (2004)
Proteoglycans in atherosclerosis and restenosis - Key roles for versican
TN Wight et al.
CIRCULATION RESEARCH (2004)
Altered patterns and synthesis of extracellular matrix macromolecules in early osteoarthritis
P Lorenzo et al.
MATRIX BIOLOGY (2004)
Aggrecan protects cartilage collagen from proteolytic cleavage
MA Pratta et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
The chondroitin sulfate proteoglycans neurocan, brevican, phosphacan, and versican are differentially regulated following spinal cord injury
LL Jones et al.
EXPERIMENTAL NEUROLOGY (2003)
Characterization of ADAMTS-9 and ADAMTS-20 as a distinct ADAMTS subfamily related to Caenorhabditis elegans GON-1
RPT Somerville et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Changes in distribution, cell associations, and protein expression levels of NG2, neurocan, phosphacan, brevican, versican V2, and tenascin-C during acute to chronic maturation of spinal cord scar tissue
XF Tang et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2003)
Differential expression of plasminogen activator inhibitor-1, tumor necrosis factor-α, TNF-α converting enzyme and ADAMTS family members in murine fat territories
G Voros et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION (2003)
Characterization of human aggrecanase 2 (ADAM-TS5): substrate specificity studies and comparison with aggrecanase 1 (ADAM-TS4)
MD Tortorella et al.
MATRIX BIOLOGY (2002)
Relative messenger RNA expression profiling of collagenases and aggrecanases in human articular chondrocytes in vivo and in vitro
B Bau et al.
ARTHRITIS AND RHEUMATISM (2002)
Cancer therapy - Matrix metalloproteinase inhibitors and cancer: Trials and tribulations
LM Coussens et al.
SCIENCE (2002)
Versican is upregulated in CNS injury and is a product of oligodendrocyte lineage cells
RA Asher et al.
JOURNAL OF NEUROSCIENCE (2002)
Human coronary smooth muscle cells internalize versican-modified LDL through LDL receptor-related protein and LDL receptors
V Llorente-Cortes et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2002)
Intact aggrecan and fragments generated by both aggrecanse and metalloproteinase-like activities are present in the developing and adult rat spinal cord and their relative abundance is altered by injury
ML Lemons et al.
JOURNAL OF NEUROSCIENCE (2001)
TIMP-3 is a potent inhibitor of aggrecanase 1 (ADAM-TS4) and aggrecanase 2 (ADAM-TS5)
M Kashiwagi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Versican V1 proteolysis in human aorta in vivo occurs at the Glu441-Ala442 bond, a site that is cleaved by recombinant ADAMTS-1 and ADAMTS-4
JD Sandy et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Mannosamine inhibits aggrecanase-mediated changes in the physical properties and biochemical composition of articular cartilage
P Patwari et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2000)