相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Bioresponsive microspheres for on-demand delivery of anti-inflammatory cytokines for articular cartilage repair
Eunjae Park et al.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A (2020)
Prolonged Release and Functionality of Interleukin-10 Encapsulated within PLA-PEG Nanoparticles
Skyla A. Duncan et al.
NANOMATERIALS (2019)
Stereotactic Body Radiation and Interleukin-12 Combination Therapy Eradicates Pancreatic Tumors by Repolarizing the Immune Microenvironment
Bradley N. Mills et al.
CELL REPORTS (2019)
Gelatin microspheres releasing transforming growth factor drive in vitro chondrogenesis of human periosteum derived cells in micromass culture
Abhijith K. Kudva et al.
ACTA BIOMATERIALIA (2019)
Recent advances and challenges of repurposing nanoparticle-based drug delivery systems to enhance cancer immunotherapy
Seungho Lim et al.
THERANOSTICS (2019)
Inhaled IL-10 Suppresses Lung Tumorigenesis via Abrogation of Inflammatory Macrophage-Th17 Cell Axis
Qingsheng Li et al.
JOURNAL OF IMMUNOLOGY (2018)
Enhanced gut barrier integrity sensitizes colon cancer to immune therapy
Neal Bhutiani et al.
ONCOIMMUNOLOGY (2018)
Experimental vaccine induces Th1-driven immune responses and resistance to Neisseria gonorrhoeae infection in a murine model
Y. Liu et al.
MUCOSAL IMMUNOLOGY (2017)
Oral IL-10 suppresses colon carcinogenesis via elimination of pathogenicCD4+ T-cells and induction of antitumor CD8+ T-cell activity
Tao Gu et al.
ONCOIMMUNOLOGY (2017)
Stabilization Challenges and Formulation Strategies Associated with Oral Biologic Drug Delivery Systems
Vu Truong-Le et al.
ADVANCED DRUG DELIVERY REVIEWS (2015)
Oral Delivery of Particulate Transforming Growth Factor Beta 1 and All-Trans Retinoic Acid Reduces Gut Inflammation in Murine Models of Inflammatory Bowel Disease
Thomas F. Conway et al.
JOURNAL OF CROHNS & COLITIS (2015)
Differences in physicochemical properties to consider in the design, evaluation and choice between microparticles and nanoparticles for drug delivery
Daniel P. Otto et al.
EXPERT OPINION ON DRUG DELIVERY (2015)
Oral Interleukin-10 Alleviates Polyposis via Neutralization of Pathogenic T-Regulatory Cells
Allen Y. Chung et al.
CANCER RESEARCH (2014)
Radio-responsive tumors exhibit greater intratumoral immune activity than nonresponsive tumors
Scott A. Gerber et al.
INTERNATIONAL JOURNAL OF CANCER (2014)
IL-10: Master Switch from Tumor-Promoting Inflammation to Antitumor Immunity
Martin Oft
CANCER IMMUNOLOGY RESEARCH (2014)
Oral delivery of proteins by biodegradable nanoparticles
Sasha H. Bakhru et al.
ADVANCED DRUG DELIVERY REVIEWS (2013)
Local antitumor effects of intratumoral delivery of rlL-2 loaded sustained-release dextran/PLGA-PLA core/shell microspheres
Haiping Zhao et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2013)
Enhancement of Adaptive Immunity to Neisseria gonorrhoeae by Local Intravaginal Administration of Microencapsulated Interleukin 12
Yingru Liu et al.
JOURNAL OF INFECTIOUS DISEASES (2013)
Particle-mediated delivery of cytokines for immunotherapy
David A. Christian et al.
IMMUNOTHERAPY (2012)
Engineered cartilage via self-assembled hMSC sheets with incorporated biodegradable gelatin microspheres releasing transforming growth factor-β1
Loran D. Solorio et al.
JOURNAL OF CONTROLLED RELEASE (2012)
Microencapsulation of Alpha Interferons in Biodegradable Microspheres
Vivian Saez et al.
JOURNAL OF INTERFERON AND CYTOKINE RESEARCH (2012)
Preparation and evaluation of poly(lactic-co-glycolic acid) microparticles as a carrier for pulmonary delivery of recombinant human interleukin-2: II. In vitro studies on aerodynamic properties of dry powder inhaler formulations
Burcu Devrim et al.
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY (2011)
Treatment of Leg Ischemia With Biodegradable Gelatin Hydrogel Microspheres Incorporating Granulocyte Colony-stimulating Factor
Itta Kawamura et al.
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2011)
Dichotomous Effects of IFN-γ on Dendritic Cell Function Determine the Extent of IL-12-Driven Antitumor T Cell Immunity
Jamie L. Harden et al.
JOURNAL OF IMMUNOLOGY (2011)
Chronic Chemoimmunotherapy Achieves Cure of Spontaneous Murine Mammary Tumors via Persistent Blockade of Posttherapy Counter-Regulation
Rachael B. Rowswell-Turner et al.
JOURNAL OF IMMUNOLOGY (2011)
Preparation of Branched Dextran Microspheres of Soluble Interferon-alpha and its Activity In Vitro and In Vivo
Hua Hong et al.
JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY (2011)
Controlled release recombinant human interferon-α2b for treating patients with chronic hepatitis C genotype 1: a phase 2a clinical trial
I. Dzyublyk et al.
JOURNAL OF VIRAL HEPATITIS (2011)
Intratumoral delivery of encapsulated IL-12, IL-18 and TNF-α in a model of metastatic breast cancer
Michael S. Sabel et al.
BREAST CANCER RESEARCH AND TREATMENT (2010)
Central Role of IFN gamma-Indoleamine 2,3-Dioxygenase Axis in Regulation of Interleukin-12-Mediated Antitumor Immunity
Tao Gu et al.
CANCER RESEARCH (2010)
Current approaches to stabilising and analysing proteins during microencapsulation in PLGA
Christopher F. van der Walle et al.
EXPERT OPINION ON DRUG DELIVERY (2009)
Central Role of Tumor-Associated CD8+ T Effector/Memory Cells in Restoring Systemic Antitumor Immunity
Mehmet O. Kilinc et al.
JOURNAL OF IMMUNOLOGY (2009)
Activated CD8+ T-Effector/Memory Cells Eliminate CD4+ CD25+ Foxp3+ T-Suppressor Cells from Tumors via FasL Mediated Apoptosis
Mehmet O. Kilinc et al.
JOURNAL OF IMMUNOLOGY (2009)
Recombinant interferon-alpha2b poly(lactic-co-glycolic acid) microspheres: pharmacokinetics-pharmacodynamics study in rhesus monkeys following intramuscular administration
Yong-ming Zhang et al.
ACTA PHARMACOLOGICA SINICA (2008)
Hydrophilic biodegradable microspheres of interferon-alpha and its pharmacokinetics in mice
Cai-Hong Zheng et al.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS (2008)
Preparation and characterization of interferon-loaded magnetic biodegradable microspheres
Shaobing Zhou et al.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS (2008)
Novel controlled-release Lemna-derived IFN-α2b (Locteron):: Pharmacokinetics, pharmacodynamics, and tolerability in a phase I clinical trial
Leo G. J. De Leede et al.
JOURNAL OF INTERFERON AND CYTOKINE RESEARCH (2008)
Transient activation of tumor-associated T-effector/memory cells promotes tumor eradication via NK-cell recruitment: minimal role for long-term T-cell immunity in cure of metastatic disease
Tao Gu et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2008)
Generation of a tumor-specific systemic response after intratumoral injection of IL-12 and IL-18-loaded polylactic acid microspheres
Michael S. Sabel et al.
JOURNAL OF IMMUNOTHERAPY (2007)
Synergistic effect of intratumoral IL-12 and TNF-α microspheres:: systemic anti-tumor immunity is mediated by both CD8+ CTL and NK cells
Michael S. Sabel et al.
SURGERY (2007)
Biodegradable chitosan scaffolds containing microspheres as carriers for controlled transforming growth factor-β1 delivery for cartilage tissue engineering
Cai Dao-zhang et al.
CHINESE MEDICAL JOURNAL (2007)
IL-12 rapidly alters the functional profile of tumor-associated and tumor-infiltrating macrophages in vitro and in vivo
Stephanie K. Watkins et al.
JOURNAL OF IMMUNOLOGY (2007)
Reversing tumor immune suppression with intratumoral IL-12:: Activation of tumor-associated T effector/memory cells, induction of T suppressor apoptosis, and infiltration of CD8+ T effectors
Mehmet O. Kilinc et al.
JOURNAL OF IMMUNOLOGY (2006)
Neoadjuvant intratumoral cytokine-loaded microspheres are superior to postoperative autologous cellular vaccines in generating systemic anti-tumor immunity
Alisha Arora et al.
JOURNAL OF SURGICAL ONCOLOGY (2006)
Enhanced immunogenicity and protective efficacy with the use of interleukin-12-encapsulated microspheres plus AS01B in tuberculosis subunit vaccination
Sang-Jun Ha et al.
INFECTION AND IMMUNITY (2006)
Chronic immune therapy induces a progressive increase in intratumoral T suppressor activity and a concurrent loss of tumor-specific CD8+ T effectors in her-2/neu transgenic mice bearing advanced spontaneous tumors
Raji E. Nair et al.
JOURNAL OF IMMUNOLOGY (2006)
Development and characterization of interleukin-18-loaded biodegradable microspheres
F. Lagarce et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2006)
Controlled release of bioactive TGF-β1 from microspheres embedded within biodegradable hydrogels
AJ DeFail et al.
BIOMATERIALS (2006)
L-12+GM-CSF microsphere therapy induces eradication of advanced spontaneous tumors in her-2/neu transgenic mice but fails to achieve long-term cure due to the inability to maintain effector T-cell activity
RE Nair et al.
JOURNAL OF IMMUNOTHERAPY (2006)
Local delivery of interleukin-2 and adriamycin is synergistic in the treatment of experimental malignant glioma
W Hsu et al.
JOURNAL OF NEURO-ONCOLOGY (2005)
Intratumoral IL-12 and TNF-α-loaded microspheres lead to regression of breast cancer and systemic antitumor immunity
MS Sabel et al.
ANNALS OF SURGICAL ONCOLOGY (2004)
Characterization of cytokine-encapsulated controlled-release microsphere adjuvants
A Sharma et al.
CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS (2004)
Tissue-engineered trachea from sheep marrow stromal cells with transforming growth factor β2 released from biodegradable microspheres in a nude rat recipient
K Kojima et al.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY (2004)
IL-2 loaded dextran microspheres with attractive histocompatibility properties for local IL-2 cancer therapy
JW Koten et al.
CYTOKINE (2003)
Biodegradable microspheres for protein delivery
VR Sinha et al.
JOURNAL OF CONTROLLED RELEASE (2003)
Local immunotherapy with interleukin-2 delivered from biodegradable polymer microspheres combined with interstitial chemotherapy: A novel treatment for experimental malignant glioma
LD Rhines et al.
NEUROSURGERY (2003)
Biodegradable micro- and nanoparticles as long-term delivery vehicles for interferon-alpha
A Sánchez et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2003)
Stabilization of recombinant interferon-α by pegylation for encapsulation in PLGA microspheres
M Diwan et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2003)
Human CD4(+) T cells present within the microenvironment of human lung tumors are mobilized by the local and sustained release of IL-12 to kill tumors in situ by indirect effects of IFN-gamma
SD Hess et al.
JOURNAL OF IMMUNOLOGY (2003)
Study on biodegradable microspheres containing recombinant interferon-α-2a
SB Zhou et al.
JOURNAL OF PHARMACY AND PHARMACOLOGY (2002)
Controlled release of interleukin-2 from chitosan microspheres
S Özbas-Turan et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2002)
New cytokine delivery system using gelatin microspheres containing interleukin-10 for experimental inflammatory bowel disease
H Nakase et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2002)
Neoadjuvant therapy with interleukin-12-loaded polylactic acid microspheres reduces local recurrence and distant metastases
MS Sabel et al.
SURGERY (2001)
Controlled local delivery of interleukin-2 by biodegradable polymers protects animals from experimental brain tumors and liver tumors
J Hanes et al.
PHARMACEUTICAL RESEARCH (2001)
Human inflammatory cells within the tumor microenvironment of lung tumor xenografts mediate tumor growth suppression in situ that depends on and is augmented by interleukin-12
Y Sugiyama et al.
JOURNAL OF IMMUNOTHERAPY (2001)
Macrophage activation for the production of immunostimulatory cytokines by delivering interleukin 1 via biodegradable microspheres
J Mullerad et al.
CYTOKINE (2000)
Promoted bone healing at a rabbit skull gap between autologous bone fragment and the surrounding intact bone with biodegradable microspheres containing transforming growth factor-β1
L Hong et al.
TISSUE ENGINEERING (2000)
Cytokines delivered by biodegradable microspheres promote effective suppression of human tumors by human peripheral blood lymphocytes in the SCID-Winn model
NK Egilmez et al.
JOURNAL OF IMMUNOTHERAPY (2000)