期刊
ENVIRONMENTAL CHEMISTRY LETTERS
卷 18, 期 4, 页码 1345-1351出版社
SPRINGER HEIDELBERG
DOI: 10.1007/s10311-020-00993-z
关键词
Sodium alginate-chitosan nanocomposite; Cinnamaldehyde; Nanocarrier properties; Larvicide formulations; Aedes aegypti larvae; Controlled release
资金
- Ministry of Education Malaysia [FRGS 2019-0003-102-02]
- Universiti Pendidikan Sultan Idris [UPSI 2019-0121-103-01]
The proliferation of mosquito-borne diseases is a major health concern worldwide. An effective strategy to prevent the transmission of mosquito-borne diseases is using larvae control. Cinnamaldehyde, a substance from the cinnamon tree, is widely used in larvicide formulations, yet applications are limited due to the poor water solubility of cinnamaldehyde. Therefore, we prepared a sodium alginate-chitosan nanocomposite as a nanocarrier of cinnamaldehyde, and we tested the effect of this encapsulated cinnamaldehyde on Aedes aegypti larvae. The nanocomposites/cinnamaldehyde formulations were characterised by Fourier transform infrared spectroscopy and nuclear magnetic resonance, which evidenced encapsulation. A ratio of 150:1 w/w nanocomposite/cinnamaldehyde induced the highest encapsulation efficiency of 95.25%, a loading capacity of 81.42%. This extended the cinnamaldehyde release by 28 h and controlled mosquito larvae.
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