期刊
CELLS TISSUES ORGANS
卷 202, 期 3-4, 页码 159-168出版社
KARGER
DOI: 10.1159/000446067
关键词
Cell culture; Contractile properties; Force; Muscle function; Skeletal muscle; Tissue engineering
Tissue-engineered skeletal muscle has the promise to be a tool for studying physiology, screening muscle-active drugs, and clinical replacement of damaged muscle. To maximize the potential benefits of engineered muscle, it is important to understand the factors required for tissue formation and how these affect muscle function. In this review, we evaluate how biomaterials, cell source, media components, and bioreactor interventions impact muscle function and phenotype. (C) 2016 S. Karger AG, Basel
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