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Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action
NM Tsankova et al.
NATURE NEUROSCIENCE (2006)
Increased MDR1 expression in normal and malignant peripheral blood mononuclear cells obtained from patients receiving depsipeptide (FR901228, FK228, NSC630176)
RW Robey et al.
CLINICAL CANCER RESEARCH (2006)
Interspecies differences in plasma protein binding of MS-275, a novel histone deacetylase inhibitor
MR Acharya et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2006)
Up-regulation of MDR1 and induction of doxorubicin resistance by histone deacetylase inhibitor depsipeptide (FK228) and ATRA in acute promyelocytic leukemia cells
Y Tabe et al.
BLOOD (2006)
The benzamide MS-275 is a potent, long-lasting brain region-selective inhibitor of histone deacetylases
MV Simonini et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Genomic instability and aging-like phenotype in the absence of mammalian SIRT6
R Mostoslavsky et al.
CELL (2006)
Targeting tumor angiogenesis with histone deacetylase inhibitors: the hydroxamic acid derivative LBH589
DZ Qian et al.
CLINICAL CANCER RESEARCH (2006)
A human protein atlas for normal and cancer tissues based on antibody proteomics
M Uhlén et al.
MOLECULAR & CELLULAR PROTEOMICS (2005)
Epigenetic changes to the MDR1 locus in response to chemotherapeutic drugs
EK Baker et al.
ONCOGENE (2005)
Identification of intra- and intermolecular disulfide bridges in the multidrug resistance transporter ABCG2
U Henriksen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Toward selective histone deacetylase inhibitor design: Homology modeling, docking studies, and molecular dynamics simulations of human class I histone deacetylases
DF Wang et al.
JOURNAL OF MEDICINAL CHEMISTRY (2005)
Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins
E Michishita et al.
MOLECULAR BIOLOGY OF THE CELL (2005)
Increased dosage of mammalian Sir2 in pancreatic β cells enhances glucose-stimulated insulin secretion in mice
KA Moynihan et al.
CELL METABOLISM (2005)
Inhibition of histone deacetylase 6 acetylates and disrupts the chaperone function of heat shock protein 90 - A novel basis for antileukemia activity of histone deacetylase inhibitors
P Bali et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Chemoresistance to depsipeptide FK228 [(E)-(1S,4S,10S,21R)-7-[(Z)-ethylidene]-4,21-diisopropyl-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo[8,7,6]-tricos-16-ene-3,6,9,22-pentanone] is mediated by reversible MDR1 induction in human cancer cell lines
JJ Xiao et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2005)
Global histone modification patterns predict risk of prostate cancer recurrence
DB Seligson et al.
NATURE (2005)
Phase I and pharmacokinetic study of MS-275, a histone deacetylase inhibitor, in patients with advanced and refractory solid tumors or lymphoma
QC Ryan et al.
JOURNAL OF CLINICAL ONCOLOGY (2005)
Effect of sodium butyrate on doxorubicin resistance and expression of multidrug resistance genes in thyroid carcinoma cells
C Massart et al.
ANTI-CANCER DRUGS (2005)
Intercellular transfer of P-glycoprotein mediates acquired multidrug resistance in tumor cells
A Levchenko et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
The breast cancer resistance protein BCRP (ABCG2) concentrates drugs and carcinogenic xenotoxins into milk
JW Jonker et al.
NATURE MEDICINE (2005)
Role of thioredoxin in the response of normal and transformed cells to histone deacetylase inhibitors
JS Ungerstedt et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Tissue distribution and hormonal regulation of the breast cancer resistance protein (Bcrp/Abcg2) in rats and mice
Y Tanaka et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Inhibitors of histone deacetylases induce tumor-selective apoptosis through activation of the death receptor pathway
A Insinga et al.
NATURE MEDICINE (2005)
Molecular evolution of the histone deacetylase family: Functional implications of phylogenetic analysis
IV Gregoretti et al.
JOURNAL OF MOLECULAR BIOLOGY (2004)
Mammalian SIRT1 represses forkhead transcription factors
MC Motta et al.
CELL (2004)
Identification of a novel estrogen response element in the breast cancer resistance protein (ABCG2) gene
PLR Ee et al.
CANCER RESEARCH (2004)
Zn2+-chelating motif-tethered short-chain fatty acids as a novel class of histone deacetylase inhibitors
Q Lu et al.
JOURNAL OF MEDICINAL CHEMISTRY (2004)
Histone deacetylase inhibitors specifically kill nonproliferating tumour cells
A Burgess et al.
ONCOGENE (2004)
The distribution of drug-efflux pumps, P-gp, BCRP, MRP1 and MRP2, in the normal blood-testis barrier and in primary testicular tumours
J Bart et al.
EUROPEAN JOURNAL OF CANCER (2004)
Histone deacetylase inhibitors upregulate death receptor 5/TRAIL-R2 and sensitize apoptosis induced by TRAIL/APO2-L in human malignant tumor cells
S Nakata et al.
ONCOGENE (2004)
Expression of histone deacetylase 8, a class I histone deacetylase, is restricted to cells showing smooth muscle differentiation in normal human tissues
D Waltregny et al.
AMERICAN JOURNAL OF PATHOLOGY (2004)
Class I histone deacetylase-selective novel synthetic inhibitors potently inhibit human tumor proliferation
JH Park et al.
CLINICAL CANCER RESEARCH (2004)
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
HY Cohen et al.
SCIENCE (2004)
The stem cell marker Bcrp/ABCG2 enhances hypoxic cell survival through interactions with heme
P Krishnamurthy et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Crystal structure of a eukaryotic zinc-dependent histone deacetylase, human HDAC8, complexed with a hydroxamic acid inhibitor
A Vannini et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Sodium 4-phenylbutyrate protects against cerebral ischemic injury
X Qi et al.
MOLECULAR PHARMACOLOGY (2004)
Sirtuins: Sir2-related NAD-dependent protein deacetylases
BJ North et al.
GENOME BIOLOGY (2004)
The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress
Y Kawaguchi et al.
CELL (2003)
Histone deacetylase inhibitors
TA Miller et al.
JOURNAL OF MEDICINAL CHEMISTRY (2003)
Transcriptional regulation of ABC drug transporters
KW Scotto
ONCOGENE (2003)
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
KT Howitz et al.
NATURE (2003)
Structure-activity relationship: analyses of p-glycoprotein substrates and inhibitors
RB Wang et al.
JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS (2003)
The histone deacetylase 9 gene encodes multiple protein isoforms
K Petrie et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Role for human SIRT2 NAD-dependent deacetylase activity in control of mitotic exit in the cell cycle
SC Dryden et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Histone deacetylases (HDACs): characterization of the classical HDAC family
AJM De Ruijter et al.
BIOCHEMICAL JOURNAL (2003)
Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease
E Hockly et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase
BJ North et al.
MOLECULAR CELL (2003)
Identification of novel isoform-selective inhibitors within class I histone deacetylases
ED Hu et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2003)
Regulation of drug and bile salt transporters in liver and intestine
GA Kullak-Ublick et al.
DRUG METABOLISM REVIEWS (2003)
In vivo destabilization of dynamic microtubules by HDAC6-mediated deacetylation
A Matsuyama et al.
EMBO JOURNAL (2002)
The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria
JW Jonker et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Localisation of breast cancer resistance protein in microvessel endothelium of human brain
HC Cooray et al.
NEUROREPORT (2002)
SIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria
P Onyango et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Cloning and functional characterization of HDAC11, a novel member of the human histone deacetylase family
L Gao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Ubiquitination of histone H2B regulates H3 methylation and gene silencing in yeast
ZW Sun et al.
NATURE (2002)
HDAC6 is a microtubule-associated deacetylase
C Hubbert et al.
NATURE (2002)
Valproic acid induces apoptosis in human leukemia cells by stimulating both caspase-dependent and -independent apoptotic signaling pathways
R Kawagoe et al.
LEUKEMIA RESEARCH (2002)
Functional divergence between histone deacetylases in fission yeast by distinct cellular localization and in vivo specificity
P Bjerling et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Functional domains of histone deacetylase-3
WM Yang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Human class I histone deacetylase complexes show enhanced catalytic activity in the presence of ATP and co-immunoprecipitate with the ATP-dependent chaperone protein Hsp70
CA Johnson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Molecular cloning and characterization of a novel histone deacetylase HDAC10
AR Guardiola et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Histone deacetylase inhibitor FK228 inhibits tumor angiogenesis
HJ Kwon et al.
INTERNATIONAL JOURNAL OF CANCER (2002)
Histone deacetylases inhibitors as anti-angiogenic agents altering vascular endothelial growth factor signaling
CF Deroanne et al.
ONCOGENE (2002)
Isolation and characterization of mammalian HDAC10, a novel histone deacetylase
HY Kao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Enzymatic activity associated with class IIHDACs is dependent on a multiprotein complex containing HDAC3 and SMRT/N-CoR
W Fischle et al.
MOLECULAR CELL (2002)
Precipitous release of methyl-CpG binding protein 2 and histone deacetylase 1 from the methylated human multidrug resistance gene (MDR1) on activation
A El-Osta et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells
M Göttlicher et al.
EMBO JOURNAL (2001)
Expression profile of histone deacetylase 1 in gastric cancer tissues
JH Choi et al.
JAPANESE JOURNAL OF CANCER RESEARCH (2001)
Mutant p53 cooperates with ETS and selectively up-regulates human MDR1 not MRP1
J Sampath et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
hSIR2SIRT1 functions as an NAD-dependent p53 deacetylase
H Vaziri et al.
CELL (2001)
Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen
CJ Phiel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Promoter characterization and genomic organization of the human breast cancer resistance protein (ATP-binding cassette transporter G2) gene
KJ Bailey-Dell et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION (2001)
Human HDAC7 histone deacetylase activity is associated with HDAC3 in vivo
W Fischle et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Histone deacetylase 4 possesses intrinsic nuclear import and export signals
AH Wang et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
Transcriptional repression by p53 through direct binding a novel DNA element
RA Johnson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
A dynamic role for HDAC7 in MEF2-mediated muscle differentiation
U Dressel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin
A Geick et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Histone acetylation and disease
S Timmermann et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2001)
Defect of histone acetyltransferase activity of the nuclear transcriptional coactivator CBP in Rubinstein-Taybi syndrome
T Murata et al.
HUMAN MOLECULAR GENETICS (2001)
Histone deacetylases induce angiogenesis by negative regulation of tumor suppressor genes
MS Kim et al.
NATURE MEDICINE (2001)
The human transcriptome map:: Clustering of highly expressed genes in chromosomal domains
H Caron et al.
SCIENCE (2001)
Aromatic hydrocarbon receptor (AhR)•AhR nuclear translocator- and p53-mediated induction of the murine multidrug resistance mdr1 gene by 3-methylcholanthrene and benzo(a)pyrene in hepatoma cells
MC Mathieu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Mdr1b facilitates p53-mediated cell death and p53 is required for Mdr1b upregulation in vivo
V Lecureur et al.
ONCOGENE (2001)
2-acetylaminofluorene up-regulates rat mdr1b expression through generating reactive oxygen species that activate NF-κB pathway
L Deng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Activation of the myocyte enhancer factor-2 transcription factor by calcium/calmodulin-dependent protein kinase-stimulated binding of 14-3-3 to histone deacetylase 5
TA McKinsey et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Role of NAD+ in the deacetylase activity of the SIR2-like proteins
J Landry et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2000)
Signal-dependent nuclear export of a histone deacetylase regulates muscle differentiation
TA McKinsey et al.
NATURE (2000)
Structure-activity relationship of P-glycoprotein substrates and modifiers
A Seelig et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2000)
Expression of members of the multidrug resistance protein family in human term placenta
MV St-Pierre et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2000)
Histone deacetylase inhibitor selectively induces p21WAF1 expression and gene-associated histone acetylation
VM Richon et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Histone deacetylases specifically down-regulate p53-dependent gene activation
LJ Juan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Regulation of histone deacetylase 4 and 5 and transcriptional activity by 14-3-3-dependent cellular localization
CM Grozinger et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
The histone deacetylase-3 complex contains nuclear receptor corepressors
YD Wen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Active maintenance of mHDA2/mHDAC6 histone-deacetylase in the cytoplasm
A Verdel et al.
CURRENT BIOLOGY (2000)
The silencing protein SIR2 and its homologs are MAD-dependent protein deacetylases
J Landry et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Cloning and characterization of a novel human. Class I histone deacetylase that functions as a transcription repressor
E Hu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
S Imai et al.
NATURE (2000)
Effects of histone deacetylase inhibitors on the Ah receptor gene promoter
PM Garrison et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2000)
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