期刊
CELL RESEARCH
卷 26, 期 3, 页码 267-268出版社
INST BIOCHEMISTRY & CELL BIOLOGY
DOI: 10.1038/cr.2016.10
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- NCI NIH HHS [R35 CA196878] Funding Source: Medline
The mammalian target of rapamycin (mTOR), also known as the mechanistic target of rapamycin, is a central cell growth regulating kinase that forms large molecular complexes in all eukaryotic cells. A paper recently published in Science reports the architecture of mTOR complex 1 (mTORC1) and provides molecular insights into the regulation and substrate selectivity of mTORC1.
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