期刊
CURRENT OPINION IN BIOTECHNOLOGY
卷 62, 期 -, 页码 168-180出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.copbio.2019.10.002
关键词
-
资金
- Max Planck Society
- European Union [763911]
- Netherlands Organization for Scientific Research (NWO) through a Rubicon Grant [019.163LW.035]
- H2020 Societal Challenges Programme [763911] Funding Source: H2020 Societal Challenges Programme
Methanol and formate are attractive microbial feedstocks as they can be sustainably produced from CO2 and renewable energy, are completely miscible, and are easy to store and transport. Here, we provide a biochemical perspective on microbial growth and bioproduction using these compounds. We show that anaerobic growth of acetogens on methanol and formate is more efficient than on H-2/CO2 or CO. We analyze the aerobic C-1 assimilation pathways and suggest that new-to-nature routes could outperform their natural counterparts. We further discuss practical bioprocessing aspects related to growth on methanol and formate, including feedstock toxicity. While challenges in realizing sustainable production from methanol and formate still exist, the utilization of these feedstocks paves the way towards a truly circular carbon economy.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据