期刊
CELL METABOLISM
卷 23, 期 6, 页码 1004-1012出版社
CELL PRESS
DOI: 10.1016/j.cmet.2016.05.013
关键词
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资金
- Jane Coffin Childs Memorial Fund for Medical Research
- NIH [R37 AG024365]
- HHMI
As the first and most direct process influencing the proteostasis capacity of a cell, regulation of translation influences lifespan across taxa. Here we highlight some of the newly discovered means by which translational regulation affects cellular proteostasis, with a focus on mechanisms that may ultimately impinge upon the aging process.
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