期刊
CRITICAL REVIEWS IN MICROBIOLOGY
卷 46, 期 2, 页码 194-212出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/1040841X.2020.1739622
关键词
Endodontic; biofilm; eradication; prevention
类别
Endodontic disease, a biofilm infection of the root canal space, is a significant cause of dental morbidity worldwide. Endodontic treatment, or root canal treatment, as it is commonly known is founded on the ability to eradicate microbial biofilm infection and prevent re-infection of the highly complex root canal space. Despite many advances in clinical endodontics we have seen little improvement in outcomes. The aim of this critical review paper is to provide a contemporary view of endodontic microbiology and biofilm polymicrobiality, provide an understanding of the host response, and how together these impact upon clinical treatment. Ultimately, it is intended to provide insight into novel opportunities and strategies for the future diagnostics, treatment, and prevention of endodontic disease.
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