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Effects and mechanisms of edible and medicinal plants on obesity: an updated review

期刊

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
卷 61, 期 12, 页码 2061-2077

出版社

TAYLOR & FRANCIS INC
DOI: 10.1080/10408398.2020.1769548

关键词

Anti-obesity; appetite; energy expenditure; mechanisms; plants

资金

  1. China Central Public-interest Scientific Institution Basal Research Fund, Chinese Academy of Agricultural Sciences [Y2020XK05]
  2. Local Financial Funds of National Agricultural Science and Technology Center, Chengdu [NASC2020KR02]
  3. National Natural Science Foundation of China [81372976]
  4. Key Project of Guangdong Provincial Science and Technology Program [2014B020205002]

向作者/读者索取更多资源

In recent years, obesity has become a global public health issue, with edible and medicinal plants showing potential as candidates for prevention and management of obesity. These plants exhibit anti-obesity activity by suppressing appetite, reducing lipid and carbohydrate absorption, regulating metabolism, increasing energy expenditure, regulating microbiota, and improving inflammation related to obesity. Further research is needed to explore safer plants with anti-obesity activity and identify specific mechanisms for combating obesity.
In recent years, obesity has become a global public health issue. It is closely associated with the occurrence of several chronic diseases, such as diabetes and cardiovascular diseases. Some edible and medicinal plants show anti-obesity activity, such as fruits, vegetables, spices, legumes, edible flowers, mushrooms, and medicinal plants. Numerous studies have indicated that these plants are potential candidates for the prevention and management of obesity. The major anti-obesity mechanisms of plants include suppressing appetite, reducing the absorption of lipids and carbohydrates, inhibiting adipogenesis and lipogenesis, regulating lipid metabolism, increasing energy expenditure, regulating gut microbiota, and improving obesity-related inflammation. In this review, the anti-obesity activity of edible and medicinal plants was summarized based on epidemiological, experimental, and clinical studies, with related mechanisms discussed, which provided the basis for the research and development of slimming products. Further studies should focus on the exploration of safer plants with anti-obesity activity and the identification of specific anti-obesity mechanisms.

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