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Biomedical applications of metal organic polygons and polyhedra (MOPs)

期刊

COORDINATION CHEMISTRY REVIEWS
卷 410, 期 -, 页码 -

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ELSEVIER SCIENCE SA
DOI: 10.1016/j.ccr.2020.213181

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MOPS; Metallotherapeutics; Antitumor agents; Drug formulation; Drug delivery

资金

  1. National Institute of Health [CA226830]

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Since the discovery and structural characterization of metal organic polygons and polyhedra (MOPs), scientists have explored their potential in various applications like catalysis, separation, storage, and sensing. In recent years, scientists have explored the potential of supramolecular MOPs in biomedical application. Pioneering works by Ehrlich, Rosenberg, Lippard, Stang and others have demonstrated that MOPs have great potential as a novel class of metallo-therapeutics that can deliver cargoes (drugs and dyes) selectively. In this article, we document the progress made over the past two decades on the biomedical applications of MOPs and discuss the future prospects of this emerging field. (C) 2020 Elsevier B.V. All rights reserved.

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