相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Effect of high uric acid on the disposition of metformin: in vivo and in vitro studies
Guoqiang Zhang et al.
BIOPHARMACEUTICS & DRUG DISPOSITION (2019)
Physiologically-Based Pharmacokinetic Modeling Analysis for Quantitative Prediction of Renal Transporter-Mediated Interactions Between Metformin and Cimetidine
Kotaro Nishiyama et al.
CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY (2019)
Optimization of a drug transporter probe cocktail: potential screening tool for transporter-mediated drug-drug interactions
Peter Stopfer et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2018)
Metformin Treatment in Patients With Type 2 Diabetes and Chronic Kidney Disease Stages 3A, 3B, or 4
Jean-Daniel Lalau et al.
DIABETES CARE (2018)
A Quantitative Systems Pharmacology Kidney Model of Diabetes Associated Renal Hyperfiltration and the Effects of SGLT Inhibitors
Pavel Balazki et al.
CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY (2018)
PBPK Modeling of the Effect of Reduced Kidney Function on the Pharmacokinetics of Drugs Excreted Renally by Organic Anion Transporters
C-H Hsueh et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2018)
Transporters Involved in Metformin Pharmacokinetics and Treatment Response
Xiaomin Liang et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2017)
Metformin and cimetidine: Physiologically based pharmacokinetic modelling to investigate transporter mediated drug-drug interactions
H. J. Burt et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2016)
In Vivo Imaging of Human 11C-Metformin in Peripheral Organs: Dosimetry, Biodistribution, and Kinetic Analyses
Lars C. Gormsen et al.
JOURNAL OF NUCLEAR MEDICINE (2016)
Pharmacokinetic Drug-Drug Interaction Assessment of LCZ696 (an Angiotensin Receptor Neprilysin Inhibitor) With Omeprazole, Metformin or Levonorgestrel-Ethinyl Estradiol in Healthy Subjects
Lu Gan et al.
CLINICAL PHARMACOLOGY IN DRUG DEVELOPMENT (2016)
Abundance of Drug Transporters in the Human Kidney Cortex as Quantified by Quantitative Targeted Proteomics
Bhagwat Prasad et al.
DRUG METABOLISM AND DISPOSITION (2016)
Metformin Is a Substrate and Inhibitor of the Human Thiamine Transporter, THTR-2 (SLC19A3)
Xiaomin Liang et al.
MOLECULAR PHARMACEUTICS (2015)
Prediction of Drug Disposition in Diabetic Patients by Means of a Physiologically Based Pharmacokinetic Model
Jia Li et al.
CLINICAL PHARMACOKINETICS (2015)
Prediction of Renal Transporter Mediated Drug-Drug Interactions for Pemetrexed Using Physiologically Based Pharmacokinetic Modeling
Maria M. Posada et al.
DRUG METABOLISM AND DISPOSITION (2015)
Four Cation-Selective Transporters Contribute to Apical Uptake and Accumulation of Metformin in Caco-2 Cell Monolayers
Tianxiang (Kevin) Han et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2015)
A Simplified PBPK Modeling Approach for Prediction of Pharmacokinetics of Four Primarily Renally Excreted and CYP3A Metabolized Compounds During Pregnancy
Binfeng Xia et al.
AAPS JOURNAL (2013)
Population Pharmacokinetics of Metformin in Healthy Subjects and Patients with Type 2 Diabetes Mellitus: Simulation of Doses According to Renal Function
Janna K. Duong et al.
CLINICAL PHARMACOKINETICS (2013)
The Effect of Novel Promoter Variants in MATE1 and MATE2 on the Pharmacokinetics and Pharmacodynamics of Metformin
S. L. Stocker et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2013)
Metformin therapy and kidney disease: a review of guidelines and proposals for metformin withdrawal around the world
Farshad Kajbaf et al.
PHARMACOEPIDEMIOLOGY AND DRUG SAFETY (2013)
A gene-gene interaction between polymorphisms in the OCT2 and MATE1 genes influences the renal clearance of metformin
Mette M. H. Christensen et al.
PHARMACOGENETICS AND GENOMICS (2013)
A Generic Integrated Physiologically based Whole-body Model of the Glucose-Insulin-Glucagon Regulatory System
S. Schaller et al.
CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY (2013)
Simulation of the pharmacokinetics of bisoprolol in healthy adults and patients with impaired renal function using whole-body physiologically based pharmacokinetic modeling
Guo-fu Li et al.
ACTA PHARMACOLOGICA SINICA (2012)
Metformin therapy in patients with chronic kidney disease
J. K. Duong et al.
DIABETES OBESITY & METABOLISM (2012)
Evaluation of Exposure Change of Nonrenally Eliminated Drugs in Patients With Chronic Kidney Disease Using Physiologically Based Pharmacokinetic Modeling and Simulation
Ping Zhao et al.
JOURNAL OF CLINICAL PHARMACOLOGY (2012)
Competitive Inhibition of the Luminal Efflux by Multidrug and Toxin Extrusions, but Not Basolateral Uptake by Organic Cation Transporter 2, Is the Likely Mechanism Underlying the Pharmacokinetic Drug-Drug Interactions Caused by Cimetidine in the Kidney
Sumito Ito et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2012)
Clinical Pharmacokinetics of Metformin
Garry G. Graham et al.
CLINICAL PHARMACOKINETICS (2011)
The pharmacogenetics of metformin and its impact on plasma metformin steady-state levels and glycosylated hemoglobin A1c
Mette M. H. Christensen et al.
PHARMACOGENETICS AND GENOMICS (2011)
Functional Characterization of the Human Organic Cation Transporter 2 Variant p.270Ala > Ser
Oliver Zolk et al.
DRUG METABOLISM AND DISPOSITION (2009)
Effect of genetic variation in the organic cation transporter 2 on the renal elimination of metformin
Ying Chen et al.
PHARMACOGENETICS AND GENOMICS (2009)
Genetic Variants of the Organic Cation Transporter 2 Influence the Disposition of Metformin
I. S. Song et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2008)
OCT2 polymorphisms and in-vivo renal functional consequence: studies with metformin and cimetidine
Zhi-Jun Wang et al.
PHARMACOGENETICS AND GENOMICS (2008)
Metformin transport by a newly cloned proton-stimulated organic cation transporter (plasma membrane monoamine transporter) expressed in human intestine
Mingyan Zhou et al.
DRUG METABOLISM AND DISPOSITION (2007)
Identification and functional characterization of a new human kidney-specific H+/organic cation antiporter, kidney-specific multidrug and toxin extrusion 2
Satohiro Masuda et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2006)
A human transporter protein that mediates the final excretion step for toxic organic cations
M Otsuka et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
分享论文
