相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。ALK inhibitor resistance in ALKF1174L-driven neuroblastoma is associated with AXL activation and induction of EMT
D. N. Debruyne et al.
ONCOGENE (2016)
Phosphatidylserine is a global immunosuppressive signal in efferocytosis, infectious disease, and cancer
R. B. Birge et al.
CELL DEATH AND DIFFERENTIATION (2016)
Efferocytosis
Sushil Kumar et al.
CURRENT BIOLOGY (2016)
TAM Receptor Signaling in Immune Homeostasis
Carla V. Rothlin et al.
ANNUAL REVIEW OF IMMUNOLOGY VOL 33 (2015)
TAM receptors, Gas6, and protein S: roles in inflammation and hemostasis
Jonathan H. M. van der Meer et al.
BLOOD (2014)
Overexpression of MERTK Receptor Tyrosine Kinase in Epithelial Cancer Cells Drives Efferocytosis in a Gain-of-Function Capacity
Khanh-Quynh N. Nguyen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Receptor Tyrosine Kinases, TYRO3, AXL, and MER, Demonstrate Distinct Patterns and Complex Regulation of Ligand-induced Activation
Wen-I Tsou et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Role of Phosphatidylserine Receptors in Enveloped Virus Infection
Kouki Morizono et al.
JOURNAL OF VIROLOGY (2014)
The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells
Magdalena Paolino et al.
NATURE (2014)
Diversification of TAM receptor tyrosine kinase function
Anna Zagorska et al.
NATURE IMMUNOLOGY (2014)
Direct regulation of GAS6/AXL signaling by HIF promotes renal metastasis through SRC and MET
Erinn B. Rankin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Differential TAM receptor-ligand-phospholipid interactions delimit differential TAM bioactivities
Erin D. Lew et al.
ELIFE (2014)
Contribution of defective PS recognition and efferocytosis to chronic inflammation and autoimmunity
Stanley Gititu Kimani et al.
FRONTIERS IN IMMUNOLOGY (2014)
The TAM family: phosphatidylserine-sensing receptor tyrosine kinases gone awry in cancer
Douglas K. Graham et al.
NATURE REVIEWS CANCER (2014)
TAM receptors in apoptotic cell clearance, autoimmunity, and cancer
Khanh-Quynh Nguyen et al.
AUTOIMMUNITY (2013)
Enveloped Viruses Disable Innate Immune Responses in Dendritic Cells by Direct Activation of TAM Receptors
Suchita Bhattacharyya et al.
CELL HOST & MICROBE (2013)
T Cell-Derived Protein S Engages TAM Receptor Signaling in Dendritic Cells to Control the Magnitude of the Immune Response
Eugenio A. Carrera Silva et al.
IMMUNITY (2013)
MerTK inhibition in tumor leukocytes decreases tumor growth and metastasis
Rebecca S. Cook et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
Axl Mediates Acquired Resistance of Head and Neck Cancer Cells to the Epidermal Growth Factor Receptor Inhibitor Erlotinib
Keith M. Giles et al.
MOLECULAR CANCER THERAPEUTICS (2013)
Analysis of alternative cleavage and polyadenylation by 3′ region extraction and deep sequencing
Mainul Hoque et al.
NATURE METHODS (2013)
The Receptor AXL Diversifies EGFR Signaling and Limits the Response to EGFR-Targeted Inhibitors in Triple-Negative Breast Cancer Cells
Aaron S. Meyer et al.
SCIENCE SIGNALING (2013)
Biology of the TAM Receptors
Greg Lemke
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2013)
The TIM and TAM Families of Phosphatidylserine Receptors Mediate Dengue Virus Entry
Laurent Meertens et al.
CELL HOST & MICROBE (2012)
Efficient Clearance of Early Apoptotic Cells by Human Macrophages Requires M2c Polarization and MerTK Induction
Gaetano Zizzo et al.
JOURNAL OF IMMUNOLOGY (2012)
Activation of the AXL kinase causes resistance to EGFR-targeted therapy in lung cancer
Zhenfeng Zhang et al.
NATURE GENETICS (2012)
Akt phosphorylation on Thr308 but not on Ser473 correlates with Akt protein kinase activity in human non-small cell lung cancer
E. E. Vincent et al.
BRITISH JOURNAL OF CANCER (2011)
The Soluble Serum Protein Gas6 Bridges Virion Envelope Phosphatidylserine to the TAM Receptor Tyrosine Kinase Axl to Mediate Viral Entry
Kouki Morizono et al.
CELL HOST & MICROBE (2011)
Targeting Axl and Mer Kinases in Cancer
Anupam Verma et al.
MOLECULAR CANCER THERAPEUTICS (2011)
Malignant cells fuel tumor growth by educating infiltrating leukocytes to produce the mitogen Gas6
Sonja Loges et al.
BLOOD (2010)
Optical imaging predicts tumor response to anti-EGFR therapy
Emily E. Helman et al.
CANCER BIOLOGY & THERAPY (2010)
R428, a Selective Small Molecule Inhibitor of Axl Kinase, Blocks Tumor Spread and Prolongs Survival in Models of Metastatic Breast Cancer
Sacha J. Holland et al.
CANCER RESEARCH (2010)
Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival
Christine Gjerdrum et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
The Mer receptor tyrosine kinase is expressed on discrete macrophage subpopulations and mainly uses Gas6 as its ligand for uptake of apoptotic cells
Wen-Hai Shao et al.
CLINICAL IMMUNOLOGY (2009)
Discovery of N-(4-(2-Amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (BMS-777607), a Selective and Orally Efficacious Inhibitor of the Met Kinase Superfamily
Gretchen M. Schroeder et al.
JOURNAL OF MEDICINAL CHEMISTRY (2009)
Autophosphorylation docking site tyr-867 in mer receptor tyrosine kinase allows for dissociation of multiple signaling pathways for phagocytosis of apoptotic cells and down-modulation of lipopolysaccharide-inducible NF-κB transcriptional activation
Nitu Tibrewal et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
A NPxY-independent β5 integrin activation signal regulates phagocytosis of apoptotic cells
Sukhwinder Singh et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
TAM receptors are pleiotropic inhibitors of the innate immune response
Carla V. Rothlin et al.
CELL (2007)
The mechanism of axl-mediated Ebola virus infection
Masayuki Shimojima et al.
JOURNAL OF INFECTIOUS DISEASES (2007)
Macrophages and dendritic cells use different Axl/Mertk/Tyro3 receptors in clearance of apoptotic cells
Heather M. Seitz et al.
JOURNAL OF IMMUNOLOGY (2007)
Tyro3 family-mediated cell entry of Ebola and Marburg viruses
Masayuki Shimojima et al.
JOURNAL OF VIROLOGY (2006)
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
A Subramanian et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
A role for Mer tyrosine kinase in αvβ5 integrin-mediated phagocytosis of apoptotic cells
Y Wu et al.
JOURNAL OF CELL SCIENCE (2005)
The receptor tyrosine kinase MerTK activates phospholipase C γ2 during recognition of apoptotic thymocytes by murine macrophages
JC Todt et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2004)
Serum-derived protein S binds to phosphatidylserine and stimulates the phagocytosis of apoptotic cells
HA Anderson et al.
NATURE IMMUNOLOGY (2003)
IFN-lambda s mediate antiviral protection through a distinct class II cytokine receptor complex
SV Kotenko et al.
NATURE IMMUNOLOGY (2003)
Activation of protein kinase C βII by the stereo-specific phosphatidylserine receptor is required for phagocytosis of apoptotic thymocytes by resident murine tissue macrophages
JC Todt et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Mer receptor tyrosine kinase signaling.: Prevention of apoptosis and alteration of cytoskeletal architecture without stimulation or proliferation.
KL Guttridge et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Homeostatic regulation of the immune system by receptor tyrosine kinases of the Tyro 3 family
QX Lu et al.
SCIENCE (2001)