期刊
CHEMISTRY OF HETEROCYCLIC COMPOUNDS
卷 56, 期 3, 页码 392-398出版社
SPRINGER
DOI: 10.1007/s10593-020-02672-x
关键词
benzosultams; thiopyranoindole; cyclizations; domino reactions; regioselectivity
A convenient catalyst-free synthesis of hitherto unknown pentacyclic benzosultam-annulated thiopyranoindole derivatives is reported which proceeds via domino Knoevenagel / intramolecular hetero-Diels-Alder reactions of (E)-N-alkyl-2-aryl-N-(2-formylphenyl)ethene-1-sulfonamides with indoline-2-thiones in water. The products were obtained regioselectively in high yields.
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