期刊
CELL AND TISSUE RESEARCH
卷 367, 期 3, 页码 643-649出版社
SPRINGER
DOI: 10.1007/s00441-016-2539-y
关键词
Pulmonary hypertension; Pulmonary remodeling; Endothelial cells; Smooth muscle cells; Lung
类别
资金
- [R24 HL123767]
- [P01 HL014985-41A1]
Pulmonary vascular remodeling is the key structural alteration in pulmonary hypertension and involves changes in the intima, media and adventitia, often with the interplay of inflammatory cells. This review examines the pathology of these changes and highlights some of the pathogenetic mechanisms that underlie the remodeling process.
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