期刊
CELL
卷 164, 期 6, 页码 1212-1225出版社
CELL PRESS
DOI: 10.1016/j.cell.2016.02.041
关键词
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资金
- New York Stem Cell Foundation
- American Cancer Society [RSG-12-059-02]
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
- Edward Mallinckrodt Jr. Foundation
- NIH [1R01AR063663-01]
- NIAMS [1K08AR066790-01]
- Global Fibrosis Foundation Grant
- James Hudson Brown-Alexander Brown Coxe Postdoctoral Fellowship
Adult stem cells across diverse organs self-renew and differentiate to maintain tissue homeostasis. How stem cells receive input to preserve tissue structure and function largely relies on their communication with surrounding cellular and non-cellular elements. As such, how tissues are organized and patterned not only reflects organ function, but also inherently hardwires networks of communication between stem cells and their environment to direct tissue homeostasis and injury repair. This review highlights how different methods of stem cell communication reflect the unique organization and function of diverse tissues.
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