期刊
CHEMBIOCHEM
卷 21, 期 17, 页码 2408-2418出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/cbic.202000123
关键词
antibacterial; antioxidation; bioorthogonal catalysis; nanozyme; tumor theranostic
资金
- National Natural Science Foundations of China [21573051, 21773044, 51761145044]
- Science Fund for Creative Research Groups of the National Natural Science Foundation of China [21721002]
- National Basic Research Programs of China [2016YFA0201601, 2018YFA0208900]
- Key Research Program of Frontier Sciences, CAS [QYZDB-SSW-SLH029]
- K. C. Wong Education Foundation [GJTD-2018-03]
- Beijing Municipal Science & Technology Commission [Z191100004819008]
- Strategic Priority Research Program of Chinese Academy of Sciences [XDB36000000]
Nanomaterials with enzyme-mimicking behavior (nanozymes) have attracted a lot of research interest recently. In comparison to natural enzymes, nanozymes hold many advantages, such as good stability, ease of production and surface functionalization. As the catalytic mechanism of nanozymes is gradually revealed, the application fields of nanozymes are also broadly explored. Beyond traditional colorimetric detection assays, nanozymes have been found to hold great potential in a variety of biomedical fields, such as tumor theranostics, antibacterial, antioxidation and bioorthogonal reactions. In this review, we summarize nanozymes consisting of different nanomaterials. In addition, we focus on the catalytic performance of nanozymes in biomedical applications. The prospects and challenges in the practical use of nanozymes are discussed at the end of this Minireview.
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