4.5 Review

Role of Microglia in Regulating Cholesterol and Tau Pathology in Alzheimer's Disease

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Immunology

Phagocytosis of full-length Tau oligomers by Actin-remodeling of activated microglia

Rashmi Das et al.

JOURNAL OF NEUROINFLAMMATION (2020)

Review Biochemistry & Molecular Biology

The Role of APOE and TREM2 in Alzheimers DiseaseCurrent Understanding and Perspectives

Cody M. Wolfe et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Article Neurosciences

Tau impairs neural circuits, dominating amyloid-beta effects, in Alzheimer models in vivo

Marc Aurel Busche et al.

NATURE NEUROSCIENCE (2019)

Review Geriatrics & Gerontology

The role of CD2AP in the Pathogenesis of Alzheimer's Disease

Qing-Qing Tao et al.

AGING AND DISEASE (2019)

Article Biochemistry & Molecular Biology

Lipid droplet proteins and metabolic diseases

Shimeng Xu et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2018)

Review Biochemistry & Molecular Biology

Prion-Like Propagation of Post-Translationally Modified Tau in Alzheimer's Disease: A Hypothesis

Shweta Kishor Sonawane et al.

JOURNAL OF MOLECULAR NEUROSCIENCE (2018)

Review Immunology

TREM2 regulates innate immunity in Alzheimer's disease

Jiang-Tao Li et al.

JOURNAL OF NEUROINFLAMMATION (2018)

Article Geriatrics & Gerontology

Loss of Trem2 in microglia leads to widespread disruption of cell coexpression networks in mouse brain

Guillermo Carbajosa et al.

NEUROBIOLOGY OF AGING (2018)

Review Neurosciences

The Role of Microglia in the Spread of Tau: Relevance for Tauopathies

Juan R. Perea et al.

FRONTIERS IN CELLULAR NEUROSCIENCE (2018)

Article Immunology

The role of microglia in processing and spreading of bioactive tau seeds in Alzheimer's disease

Sarah C. Hoppe et al.

JOURNAL OF NEUROINFLAMMATION (2018)

Review Biochemistry & Molecular Biology

Intracellular and Plasma Membrane Events in Cholesterol Transport and Homeostasis

Dmitry Y. Litvinov et al.

JOURNAL OF LIPIDS (2018)

Article Neurosciences

TREM2 Promotes Microglial Survival by Activating Wnt/β-Catenin Pathway

Honghua Zheng et al.

JOURNAL OF NEUROSCIENCE (2017)

Article Neurosciences

Absence of CX3CR1 impairs the internalization of Tau by microglia

Marta Bolos et al.

MOLECULAR NEURODEGENERATION (2017)

Review Neurosciences

TREM2 in Neurodegenerative Diseases

Taylor R. Jay et al.

MOLECULAR NEURODEGENERATION (2017)

Review Neurosciences

Elucidating the Role of TREM2 in Alzheimer's Disease

Jason D. Ulrich et al.

NEURON (2017)

Article Biochemistry & Molecular Biology

TREM2 deficiency impairs chemotaxis and microglial responses to neuronal injury

Fargol Mazaheri et al.

EMBO REPORTS (2017)

Review Neurosciences

Tau in physiology and pathology

Yipeng Wang et al.

NATURE REVIEWS NEUROSCIENCE (2016)

Review Clinical Neurology

Hyperphosphorylation determines both the spread and the morphology of tau pathology

Wen Hu et al.

ALZHEIMERS & DEMENTIA (2016)

Review Neurosciences

Tau and tauopathies

Thomas Arendt et al.

BRAIN RESEARCH BULLETIN (2016)

Review Medicine, Research & Experimental

The amyloid hypothesis of Alzheimer's disease at 25years

Dennis J. Selkoe et al.

EMBO MOLECULAR MEDICINE (2016)

Review Biochemistry & Molecular Biology

Effects of bile acids on neurological function and disease

Matthew McMillin et al.

FASEB JOURNAL (2016)

Review Genetics & Heredity

Apolipoprotein E: from cardiovascular disease to neurodegenerative disorders

Robert W. Mahley

JOURNAL OF MOLECULAR MEDICINE-JMM (2016)

Article Cell Biology

Tau and Aβ imaging, CSF measures, and cognition in Alzheimer's disease

Matthew R. Brier et al.

SCIENCE TRANSLATIONAL MEDICINE (2016)

Article Cell Biology

Loss of Bin1 Promotes the Propagation of Tau Pathology

Sara Calafate et al.

CELL REPORTS (2016)

Review Geriatrics & Gerontology

Tau Structures

Jesus Avila et al.

FRONTIERS IN AGING NEUROSCIENCE (2016)

Article Neurosciences

Direct Evidence of Internalization of Tau by Microglia In Vitro and In Vivo

Marta Bolos et al.

JOURNAL OF ALZHEIMERS DISEASE (2016)

Review Biochemistry & Molecular Biology

The impairment of cholesterol metabolism in Huntington disease

Valerio Leoni et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2015)

Review Neurosciences

Alzheimer's Disease Risk Genes and Mechanisms of Disease Pathogenesis

Celeste M. Karch et al.

BIOLOGICAL PSYCHIATRY (2015)

Review Cell Biology

Phosphatidylinositol-3,4,5-Triphosphate and Cellular Signaling: Implications for Obesity and Diabetes

Prasenjit Manna et al.

CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2015)

Review Biochemistry & Molecular Biology

Acyl-CoA:cholesterol acyltransferases (ACATs/SOATs): Enzymes with multiple sterols as substrates and as activators

Maximillian A. Rogers et al.

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2015)

Review Neurosciences

Genetics ignite focus on microglial inflammation in Alzheimer's disease

Manasi Malik et al.

MOLECULAR NEURODEGENERATION (2015)

Review Immunology

Innate immunity in Alzheimer's disease

Michael T. Heneka et al.

NATURE IMMUNOLOGY (2015)

Review Clinical Neurology

Clearance systems in the brain-implications for Alzheimer disease

Jenna M. Tarasoff-Conway et al.

NATURE REVIEWS NEUROLOGY (2015)

Review Anatomy & Morphology

Pio del Rio Hortega and the discovery of the oligodendrocytes

Fernando Perez-Cerda et al.

FRONTIERS IN NEUROANATOMY (2015)

Review Geriatrics & Gerontology

Oxidized cholesterol as the driving force behind the development of Alzheimer's disease

Paola Gamba et al.

FRONTIERS IN AGING NEUROSCIENCE (2015)

Review Cell Biology

Cholesterol metabolism and homeostasis in the brain

Juan Zhang et al.

PROTEIN & CELL (2015)

Article Endocrinology & Metabolism

Complex lipid trafficking in Niemann-Pick disease type C

Marie T. Vanier

JOURNAL OF INHERITED METABOLIC DISEASE (2015)

Article Multidisciplinary Sciences

Endophilin marks and controls a clathrin-independent endocytic pathway

Emmanuel Boucrot et al.

NATURE (2015)

Article Clinical Neurology

beta-Amyloid Is Transmitted via Neuronal Connections along Axonal Membranes

Ha-Lim Song et al.

ANNALS OF NEUROLOGY (2014)

Review Immunology

Microglia Development and Function

Debasis Nayak et al.

ANNUAL REVIEW OF IMMUNOLOGY, VOL 32 (2014)

Article Biochemistry & Molecular Biology

Action mechanisms of Liver X Receptors

Chiara Gabbi et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2014)

Article Biochemistry & Molecular Biology

Functional screening in Drosophila identifies Alzheimer's disease susceptibility genes and implicates Tau-mediated mechanisms

Joshua M. Shulman et al.

HUMAN MOLECULAR GENETICS (2014)

Article Biochemistry & Molecular Biology

CD33: increased inclusion of exon 2 implicates the Ig V-set domain in Alzheimers disease susceptibility

Towfique Raj et al.

HUMAN MOLECULAR GENETICS (2014)

Review Genetics & Heredity

Amphiphysin 2 (BIN1) in physiology and diseases

Ivana Prokic et al.

JOURNAL OF MOLECULAR MEDICINE-JMM (2014)

Article Pathology

Tau Pathology Induces Intraneuronal Cholesterol Accumulation

Frauke Glöckner et al.

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2014)

Article Biochemistry & Molecular Biology

Heparan sulfate proteoglycan as a cell-surface endocytosis receptor

Helena C. Christianson et al.

MATRIX BIOLOGY (2014)

Review Neurosciences

Alzheimer's Disease Genetics: From the Bench to the Clinic

Celeste M. Karch et al.

NEURON (2014)

Review Neurosciences

The role of extracellular Tau in the spreading of neurofibrillary pathology

Miguel Medina et al.

FRONTIERS IN CELLULAR NEUROSCIENCE (2014)

Review Geriatrics & Gerontology

Metals and cholesterol: two sides of the same coin in Alzheimer's disease pathology

Bruce X. Wong et al.

FRONTIERS IN AGING NEUROSCIENCE (2014)

Review Geriatrics & Gerontology

The low-density lipoprotein receptor-related protein 1 and amyloid-β clearance in Alzheimer's disease

Takahisa Kanekiyo et al.

FRONTIERS IN AGING NEUROSCIENCE (2014)

Review Endocrinology & Metabolism

Brain alterations and clinical symptoms of dementia in diabetes: A beta/tau-dependent and independent mechanism

Naoyuki Sato et al.

FRONTIERS IN ENDOCRINOLOGY (2014)

Article Neurosciences

CD33 Alzheimer's Risk-Altering Polymorphism, CD33 Expression, and Exon 2 Splicing

Manasi Malik et al.

JOURNAL OF NEUROSCIENCE (2013)

Article Neurosciences

Neuronal Clearance of Amyloid-β by Endocytic Receptor LRP1

Takahisa Kanekiyo et al.

JOURNAL OF NEUROSCIENCE (2013)

Article Biochemistry & Molecular Biology

Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology

J. Chapuis et al.

MOLECULAR PSYCHIATRY (2013)

Article Multidisciplinary Sciences

NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice

Michael T. Heneka et al.

NATURE (2013)

Article Genetics & Heredity

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

Jean-Charles Lambert et al.

NATURE GENETICS (2013)

Article Neurosciences

CD33 Alzheimer's disease locus: altered monocyte function and amyloid biology

Elizabeth M. Bradshaw et al.

NATURE NEUROSCIENCE (2013)

Article Medicine, General & Internal

Variant of TREM2 Associated with the Risk of Alzheimer's Disease

Thorlakur Jonsson et al.

NEW ENGLAND JOURNAL OF MEDICINE (2013)

Article Medicine, General & Internal

TREM2 Variants in Alzheimer's Disease

Rita Guerreiro et al.

NEW ENGLAND JOURNAL OF MEDICINE (2013)

Article Multidisciplinary Sciences

Adaptor complex AP2/PICALM, through interaction with LC3, targets Alzheimer's APP-CTF for terminal degradation via autophagy

Yuan Tian et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Clinical Neurology

Is There a Cerebral Lymphatic System?

Jeffrey J. Iliff et al.

STROKE (2013)

Review Biochemistry & Molecular Biology

Bridging integrator 1 (BIN1): form, function, and Alzheimer's disease

Meng-Shan Tan et al.

TRENDS IN MOLECULAR MEDICINE (2013)

Review Clinical Neurology

Evidence for impaired amyloid beta clearance in Alzheimer's disease

Kristin R. Wildsmith et al.

ALZHEIMERS RESEARCH & THERAPY (2013)

Review Clinical Neurology

The Involvement of Cholinergic Neurons in the Spreading of Tau Pathology

Diana Simon et al.

FRONTIERS IN NEUROLOGY (2013)

Review Endocrinology & Metabolism

Lipid Metabolism and Neuroinflammation in Alzheimer's Disease: A Role for Liver X Receptors

Jihong Kang et al.

ENDOCRINE REVIEWS (2012)

Article Biochemistry & Molecular Biology

Differential Regulation of Amyloid-β Endocytic Trafficking and Lysosomal Degradation by Apolipoprotein E Isoforms

Jie Li et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2012)

Article Biochemistry & Molecular Biology

Tissue-Specific Alternative Splicing Remodels Protein-Protein Interaction Networks

Jonathan D. Ellis et al.

MOLECULAR CELL (2012)

Article Biochemistry & Molecular Biology

High frequency of potentially pathogenic SORL1 mutations in autosomal dominant early-onset Alzheimer disease

C. Pottier et al.

MOLECULAR PSYCHIATRY (2012)

Article Medicine, Research & Experimental

Apolipoprotein E and Apolipoprotein E Receptors: Normal Biology and Roles in Alzheimer Disease

David M. Holtzman et al.

COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2012)

Review Pharmacology & Pharmacy

Microglia function in Alzheimer's disease

Egle Solito et al.

FRONTIERS IN PHARMACOLOGY (2012)

Review Endocrinology & Metabolism

Cholesterol: Its Regulation and Role in Central Nervous System Disorders

Matthias Orth et al.

CHOLESTEROL (2012)

Review Neurosciences

The Role of Tau in Alzheimer's Disease and Related Disorders

Rodrigo Medeiros et al.

CNS NEUROSCIENCE & THERAPEUTICS (2011)

Review Neurosciences

Statins: Multiple neuroprotective mechanisms in neurodegenerative diseases

Qing Wang et al.

EXPERIMENTAL NEUROLOGY (2011)

Article Biochemistry & Molecular Biology

Characterization of RIN3 as a Guanine Nucleotide Exchange Factor for the Rab5 Subfamily GTPase Rab31

Hiroaki Kajiho et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Article Biochemistry & Molecular Biology

Pathogenesis of the Tauopathies

Michel Goedert et al.

JOURNAL OF MOLECULAR NEUROSCIENCE (2011)

Article Clinical Neurology

Dietary Cholesterol and Its Effect on Tau Protein: A Study in Apolipoprotein E-Deficient and P301L Human Tau Mice

Frauke Gloeckner et al.

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2011)

Review Neurosciences

Linking lipids to Alzheimer's disease: cholesterol and beyond

Gilbert Di Paolo et al.

NATURE REVIEWS NEUROSCIENCE (2011)

Review Biochemistry & Molecular Biology

Cholesterol metabolism in neurons and astrocytes

Frank W. Pfrieger et al.

PROGRESS IN LIPID RESEARCH (2011)

Article Multidisciplinary Sciences

Synaptic Pruning by Microglia Is Necessary for Normal Brain Development

Rosa C. Paolicelli et al.

SCIENCE (2011)

Editorial Material Medicine, Research & Experimental

The Revitalized Tau Hypothesis on Alzheimer's Disease

Ricardo B. Maccioni et al.

ARCHIVES OF MEDICAL RESEARCH (2010)

Article Clinical Neurology

Replication of CLU, CR1, and PICALM Associations With Alzheimer Disease

Minerva M. Carrasquillo et al.

ARCHIVES OF NEUROLOGY (2010)

Article Neurosciences

Epistasis Between Intracellular Cholesterol Trafficking-Related Genes (NPC1 and ABCA1) and Alzheimer's Disease Risk

Eloy Rodriguez-Rodriguez et al.

JOURNAL OF ALZHEIMERS DISEASE (2010)

Article Biochemistry & Molecular Biology

Low Density Lipoprotein Receptor-related Protein (LRP1) Regulates Rac1 and RhoA Reciprocally to Control Schwann Cell Adhesion and Migration

Elisabetta Mantuano et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Article Biochemistry & Molecular Biology

Human Tau Isoforms Assemble into Ribbon-like Fibrils That Display Polymorphic Structure and Stability

Susanne Wegmann et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Article Cell Biology

Cholesterol reduction impairs exocytosis of synaptic vesicles

Anna Linetti et al.

JOURNAL OF CELL SCIENCE (2010)

Review Pharmacology & Pharmacy

Altered cholesterol and fatty acid metabolism in Huntington disease

Robert C. Block et al.

JOURNAL OF CLINICAL LIPIDOLOGY (2010)

Article Biochemistry & Molecular Biology

CD2AP is indispensable to multistep cytotoxic process by NK cells

Yuting Ma et al.

MOLECULAR IMMUNOLOGY (2010)

Article Neurosciences

Endocytic pathways mediating oligomeric Aβ42 neurotoxicity

Chunjiang Yu et al.

MOLECULAR NEURODEGENERATION (2010)

Article Biochemistry & Molecular Biology

Linking Alzheimer's disease to insulin resistance: the FoxO response to oxidative stress

K. N. Manolopoulos et al.

MOLECULAR PSYCHIATRY (2010)

Article Neurosciences

Regulation of Tau Pathology by the Microglial Fractalkine Receptor

Kiran Bhaskar et al.

NEURON (2010)

Article Multidisciplinary Sciences

ACAT1 gene ablation increases 24(S)-hydroxycholesterol content in the brain and ameliorates amyloid pathology in mice with AD

Elena Y. Bryleva et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Biochemistry & Molecular Biology

TREM2-and DAP12-Dependent Activation of PI3K Requires DAP10 and Is Inhibited by SHIP1

Qisheng Peng et al.

SCIENCE SIGNALING (2010)

Review Clinical Neurology

Mechanisms of tau-induced neurodegeneration

Khalid Iqbal et al.

ACTA NEUROPATHOLOGICA (2009)

Review Biochemistry & Molecular Biology

Central nervous system: cholesterol turnover, brain development and neurodegeneration

John M. Dietschy

BIOLOGICAL CHEMISTRY (2009)

Review Clinical Neurology

Metabolic links between diabetes and Alzheimer's disease

Pamela A. Maher et al.

EXPERT REVIEW OF NEUROTHERAPEUTICS (2009)

Review Biochemistry & Molecular Biology

Attenuation of AD-like neuropathology by harnessing peripheral immune cells: local elevation of IL-10 and MMP-9

Maya Koronyo-Hamaoui et al.

JOURNAL OF NEUROCHEMISTRY (2009)

Article Neurosciences

Mechanism underlying apolipoprotein E (ApoE) isoform-dependent lipid efflux from neural cells in culture

Hirohisa Minagawa et al.

JOURNAL OF NEUROSCIENCE RESEARCH (2009)

Review Biochemistry & Molecular Biology

Hyperphosphorylation of Microtubule-Associated Protein Tau: A Promising Therapeutic Target for Alzheimer Disease

C. -X. Gong et al.

CURRENT MEDICINAL CHEMISTRY (2008)

Article Biochemistry & Molecular Biology

Regulation of cholesterologenesis by the oxysterol receptor, LXRα

Yongjun Wang et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Neurosciences

Neuronal expression and subcellular localization of cholesterol 24-hydroxylase in the mouse brain

Denise M. O. Ramirez et al.

JOURNAL OF COMPARATIVE NEUROLOGY (2008)

Review Biochemistry & Molecular Biology

Role of ATP-binding cassette transporters in brain lipid transport and neurological disease

Woojin Scott Kim et al.

JOURNAL OF NEUROCHEMISTRY (2008)

Review Neurosciences

Tau exon 10 alternative splicing and tauopathies

Fei Liu et al.

MOLECULAR NEURODEGENERATION (2008)

Review Neurosciences

Lipid rafts, cholesterol, and the brain

Zeljka Korade et al.

NEUROPHARMACOLOGY (2008)

Article Cell Biology

LRP-1 A new modulator of cytoskeleton dynamics and adhesive complex turnover in cancer cells

Stephane Dedieu et al.

CELL ADHESION & MIGRATION (2008)

Article Biochemistry & Molecular Biology

The GSK3 hypothesis of Alzheimer's disease

Claudie Hooper et al.

JOURNAL OF NEUROCHEMISTRY (2008)

Article Biochemistry & Molecular Biology

ABCG1 and ABCG4 are coexpressed in neurons and astrocytes of the CNS and regulate cholesterol homeostasis through SREBP-2

Paul T. Tarr et al.

JOURNAL OF LIPID RESEARCH (2008)

Article Biochemistry & Molecular Biology

cAMP-induced expression of ABCA1 is associated with MAP-kinase-pathway activation

Thomas Witzlack et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)

Review Cell Biology

Pathways of clathrin-independent endocytosis

Satyajit Mayor et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)

Article Multidisciplinary Sciences

Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: Oxysterols block transport by binding to Insig

Arun Radhakrishnan et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Review Neurosciences

Tau-mediated neurodegeneration in Alzheimer's disease and related disorders

Carlo Ballatore et al.

NATURE REVIEWS NEUROSCIENCE (2007)

Article Biochemistry & Molecular Biology

Phosphorylation inhibits turnover of the tau protein by the proteasome:: influence of RCAN1 and oxidative stress

Diana Poppek et al.

BIOCHEMICAL JOURNAL (2006)

Review Multidisciplinary Sciences

Apolipoprotein E4: A causative factor and therapeutic target in neuropathology including Alzheimer's disease

RW Mahley et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Biochemistry & Molecular Biology

Expression of ABCG1, but not ABCA1, correlates with cholesterol release by cerebellar astroglia

B Karten et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2006)

Article Clinical Neurology

Oxysterols and Alzheimer's disease

I. Bjorkhem et al.

ACTA NEUROLOGICA SCANDINAVICA (2006)

Article Biochemistry & Molecular Biology

High cholesterol diet induces tau hyperphosphorylation in apolipoprotein E deficient mice

A Rahman et al.

FEBS LETTERS (2005)

Article Multidisciplinary Sciences

Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein

OM Andersen et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Review Medicine, Research & Experimental

The genetic epidemidogy of neurodegenerative disease

L Bertram et al.

JOURNAL OF CLINICAL INVESTIGATION (2005)

Review Biochemistry & Molecular Biology

Tau gene alternative splicing: expression patterns, regulation and modulation of function in normal brain and neurodegenerative diseases

A Andreadis

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2005)

Review Biochemistry & Molecular Biology

Tau pathology in Alzheimer disease and other tauopathies

K Iqbal et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2005)

Article Biochemistry & Molecular Biology

A novel cholesterol stain reveals early neuronal cholesterol accumulation in the Niemann-Pick type C1 mouse brain

PC Reid et al.

JOURNAL OF LIPID RESEARCH (2004)

Article Biochemistry & Molecular Biology

Pseudophosphorylation of tau protein alters its ability for self-aggregation

C Haase et al.

JOURNAL OF NEUROCHEMISTRY (2004)

Article Biochemistry & Molecular Biology

Promotion of hyperphosphorylation by frontotemporal dementia tau mutations

AD Alonso et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Review Biochemistry & Molecular Biology

Cholesterol metabolism in the central nervous system during early development and in the mature animal

JM Dietschy et al.

JOURNAL OF LIPID RESEARCH (2004)

Review Hematology

Intracellular cholesterol transport

RE Soccio et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2004)

Review Medicine, General & Internal

Drug therapy - Alzheimer's disease

JL Cummings

NEW ENGLAND JOURNAL OF MEDICINE (2004)

Review Hematology

Brain cholesterol:: Long secret life behind a barrier

I Björkhem et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2004)

Article Biochemistry & Molecular Biology

APOE genotype effects on Alzheimer's disease onset and epidemiology

JW Ashford

JOURNAL OF MOLECULAR NEUROSCIENCE (2004)

Review Medicine, General & Internal

CD2-associated protein and glomerular disease

G Wolf et al.

LANCET (2003)

Article Multidisciplinary Sciences

GSK-3α regulates production of Alzheimer's disease amyloid-β peptides

CJ Phiel et al.

NATURE (2003)

Review Neurosciences

Alzheimer's disease: the cholesterol connection

L Puglielli et al.

NATURE NEUROSCIENCE (2003)

Article Biochemistry & Molecular Biology

Membrane-bound enzymes of cholesterol synthesis from lanosterol

JL Gaylor

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)

Review Multidisciplinary Sciences

Insulin signalling and the regulation of glucose and lipid metabolism

AR Saltiel et al.

NATURE (2001)

Review Biochemistry & Molecular Biology

Cholesterol metabolism in the brain

JM Dietschy et al.

CURRENT OPINION IN LIPIDOLOGY (2001)

Article Biochemistry & Molecular Biology

Cholesterol-dependent modulation of tau phosphorylation in cultured neurons

QW Fan et al.

JOURNAL OF NEUROCHEMISTRY (2001)

Article Medicine, Research & Experimental

Clearance of Alzheimer's amyloid-β1-40 peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier

M Shibata et al.

JOURNAL OF CLINICAL INVESTIGATION (2000)

Article Multidisciplinary Sciences

Dissecting the role of the Golgi complex and lipid rafts in biosynthetic transport of cholesterol to the cell surface

S Heino et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)