期刊
CELL STEM CELL
卷 26, 期 5, 页码 629-631出版社
CELL PRESS
DOI: 10.1016/j.stem.2020.04.004
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资金
- NICHD NIH HHS [R21 HD091512] Funding Source: Medline
- NINDS NIH HHS [R01 NS102382] Funding Source: Medline
Gosselin et al. (2017) reported that a tissue-environment-dependent transcriptional network specifies human microglia identity and that in vitro environments drastically alter the human microglia transcriptome. Recent 3-dimensional culture and human-mouse chimeric brain modeling systems developed using human pluripotent stem cells help us understand the complex properties of human microglia.
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