期刊
CANCER
卷 126, 期 16, 页码 3750-3757出版社
WILEY
DOI: 10.1002/cncr.32981
关键词
cancer; Functional Assessment of Cancer Therapy-General 7-item scale (FACT-G7); metastatic; outcomes assessment; palliative care; quality of life; validation studies
类别
资金
- Canadian Institutes of Health Research [152996]
- Canadian Cancer Society [017257, 020509]
- Ontario Ministry of Health and Long Term Care
- Rose Family Chair in Supportive Care, Faculty of Medicine, University of Toronto
Background Assessing quality of life is essential for individuals with advanced cancer, but lengthy assessments can be burdensome. The authors investigated the psychometric characteristics of the FACT-G7, a 7-item quality-of-life measure derived from the Functional Assessment of Cancer Therapy-General (FACT-G) scale, in advanced cancer. Methods Data were obtained from outpatients with advanced cancer who were enrolled in a randomized controlled trial of early palliative care. At baseline, 228 intervention participants and 233 control participants (N = 461) completed the FACT-G and measures of symptom severity, quality of life near the end of life, problematic medical communication, and satisfaction with care. Follow-up measures were administered monthly for 4 months. Results The FACT-G7 showed good internal consistency (Cronbach alpha = .72-.80), and its single-factor structure was supported. It correlated strongly with the FACT-G total, physical, and functional indices and with symptom severity (absolute r = 0.73-0.92); more moderately with the FACT-G emotional index and with symptom impact and preparation for the end of life (r = .40-.71); and least with the FACT-G social/family index and with relationship with health care provider, life completion, problematic medical communication, and care satisfaction measures (absolute r = .26-.44). Eastern Cooperative Oncology Group performance status groups differed on FACT-G7 scores, as expected (all P < .001). Improvements in FACT-G7 scores in the intervention group compared with the control group at 3-month (P = .049) and 4-month (P = .034) follow-up supported responsiveness to change and somewhat greater sensitivity than the FACT-G scores. Conclusions The FACT-G7 is a valid, brief measure particularly of the physical and functional facets of quality of life. It may enable rapid quality-of-life assessments in patients with advanced cancer.
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