期刊
BIOFOULING
卷 36, 期 2, 页码 234-244出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/08927014.2020.1755842
关键词
Biofilms; Candida albicans; Pseudomonas aeruginosa; Staphylococcus epidermidis; Bioactive glass
资金
- FAPESP (Sao Paulo Research Foundation) [2018/17073-4, 2013/07793-6]
- CAPES (Coordination for the Improvement of Higher Education Personnel - Brazil) [001]
This study evaluated adhesion and biofilm formation by Candida albicans, Pseudomonas aeruginosa and Staphylococcus epidermidis on surfaces of titanium (Ti) and titanium coated with F18 Bioactive Glass (BGF18). Biofilms were grown and the areas coated with biofilm were determined after 2, 4 and 8 h. Microscopy techniques were applied in order to visualize the structure of the mature biofilm and the extracellular matrix. On the BGF18 specimens, there was less biofilm formation by C. albicans and S. epidermidis after incubation for 8 h. For P. aeruginosa biofilm, a reduction was observed after incubation for 4 h, and it remained reduced after 8 h on BGF18 specimens. All biofilm matrices seemed to be thicker on BGF18 surface than on titanium surfaces. BGF18 showed significant anti-biofilm activity in comparison with Ti in the initial periods of biofilm formation; however, there was extensive biofilm after incubation for 48 h.
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