期刊
BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY
卷 33, 期 6, 页码 -出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.berh.2020.101498
关键词
Microbiome; 16S rRNA gene sequencing; Metagenomics; Metabolomics; Mucosal immunity; Tolerance; Dysbiosis; Ecological model
类别
资金
- NIAMS Intramural Research Program [Z01 AR041184]
The human microbiome is impressively immense and participates in many aspects of our health and wellness, particularly involving the development and maintenance of a healthy immune system. Not only do our microbes teach the immune system to fight infection, they also teach immune tolerance and help maintain homeostasis. From this knowledge, we have learned that the loss of tolerance to microbiota in both innate and adaptive processes plays an important role in immune-mediated and autoimmune disease. In this chapter, we will be discussing about methods used to study the microbiome, both old and new methods, fundamental concepts that have taken hold within the field, and how these principles relate to rheumatology, including thoughts on how microbiome research may be focused in the next decade. (C) 2020 Elsevier Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据