期刊
BIOTECHNOLOGY AND BIOENGINEERING
卷 113, 期 6, 页码 1155-1163出版社
WILEY
DOI: 10.1002/bit.25869
关键词
tissue engineering; modular engineering; self-assembly; stimuli-responsive polymers; delivery of biologics; cell-assembled devices
资金
- Science Foundation Ireland [09/SRC/B1794, 13/RC/2073]
- Industry-Academia Partnerships and Pathways (IAPP) [251385, EU FP7/2007-2013]
- NMP award, Green Nano Mesh Project [263289]
- Health Research Board, Health Research Awards Programme [HRA_POR/2011/84]
- Irish Research Council [RS/2012/82]
- Irish Research Council, Government of Ireland Postgraduate Scholarship Scheme [GOIPG/2014/385]
- European Union 7th Framework Programme ITN AngioMatTrain [317304]
- Teagasc Walsh Fellowship [2014045]
- ReValueProtein Research Project [11/F/043]
- Department of Agriculture, Food, and the Marine (DAFM)
- European Regional Development [13/RC/2073]
Self-assembly in tissue engineering refers to the spontaneous chemical or biological association of components to form a distinct functional construct, reminiscent of native tissue. Such self-assembled systems have been widely used to develop platforms for the delivery of therapeutic and/or bioactive molecules and various cell populations. Tissue morphology and functional characteristics have been recapitulated in several self-assembled constructs, designed to incorporate stimuli responsiveness and controlled architecture through spatial confinement or field manipulation. In parallel, owing to substantial functional properties, scaffold-free cell-assembled devices have aided in the development of functional neotissues for various clinical targets. Herein, we discuss recent advancements and future aspirations in scaffold and scaffold-free self-assembled devices for regenerative medicine purposes. (C) 2015 Wiley Periodicals, Inc.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据