期刊
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
卷 59, 期 35, 页码 15238-15243出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.202003656
关键词
annulation; heteroarenes; radical cations; synthetic methods; pi-extension
资金
- National Natural Science Foundation of China [21520102003]
- Hubei Province Natural Science Foundation of China [2017CFA010]
Considering their unique electronic properties and diverse biological activities, regioselective access to fused aromatic compounds is significantly important in the field of organic materials and pharmaceutical science. Herein, we developed electrochemical oxidative [4+2] annulation reactions of heterobiaryl compounds with alkynes or alkenes, leading to the formation of several polycyclic heteroaromatic compounds. This electrosynthetic methodology serves for the straightforward pi-extension of unfunctionalized heterobiaryl compounds. The requirements of additional oxidants and prefunctionalization of starting materials are obviated. Through the in situ generation of heterobiaryl radical cation intermediates, various fused aromatic compounds were obtained with good yields and excellent regioselectivity.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据