期刊
ADVANCED SYNTHESIS & CATALYSIS
卷 362, 期 13, 页码 2744-2754出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.202000238
关键词
Asymmetric catalysis; chiral 3-amino oxindoles; aza Friedel-Crafts reaction; bifunctional thioureas; flow chemistry; supported catalysts
资金
- Junta de Castilla y Leon [FEDER-VA115P17, VA149G18]
Supported cinchone-derived thioureas promote highly enantioselective aza-Friedel-Crafts reaction of different naphthols with a variety of N-Boc ketimines derived from isatin. The catalysts are recoverable and reusable, and one of the supported catalysts has been used in a flow process allowing the synthesis of 3-amino-2-oxindole derivatives in multigram scale with high yield and enantioselectivity.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据