相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。The Good, the Bad and the Unknown of CD38 in the Metabolic Microenvironment and Immune Cell Functionality of Solid Tumors
Jessica M. Konen et al.
CELLS (2020)
Beyond Energy Metabolism: Exploiting the Additional Roles of NAMPT for Cancer Therapy
Christine M. Heske
FRONTIERS IN ONCOLOGY (2020)
The copper-sensing transcription factor Mac1, the histone deacetylase Hst1, and nicotinic acid regulate de novo NAD+ biosynthesis in budding yeast
Christol James Theoga Raj et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2019)
Co-translational, Post-translational, and Non-catalytic Roles of N-Terminal Acetyltransferases
Henriette Aksnes et al.
MOLECULAR CELL (2019)
NAD tagSeq reveals that NAD+-capped RNAs are mostly produced from a large number of protein-coding genes in Arabidopsis
Hailei Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Dual control of NAD+ synthesis by purine metabolites in yeast
Benoit Pinson et al.
ELIFE (2019)
Keeping the balance in NAD metabolism
Oyvind Stromland et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2019)
Implications of altered NAD metabolism in metabolic disorders
Keisuke Okabe et al.
JOURNAL OF BIOMEDICAL SCIENCE (2019)
Nicotinamide Adenine Dinucleotide Metabolism and Neurodegeneration
Mariana Pehar et al.
ANTIOXIDANTS & REDOX SIGNALING (2018)
NAD-biosynthetic enzyme NMNAT1 reduces early behavioral impairment in the htau mouse model of tauopathy
Francesca Rossi et al.
BEHAVIOURAL BRAIN RESEARCH (2018)
NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and NR
Jun Yoshino et al.
CELL METABOLISM (2018)
A functional link between NAD(+) homeostasis and N-terminal protein acetylation in Saccharomyces cerevisiae
Trevor Croft et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2018)
De novo NAD+ biosynthetic impairment in acute kidney injury in humans
Ali Poyan Mehr et al.
NATURE MEDICINE (2018)
Pharmacological bypass of NAD+ salvage pathway protects neurons from chemotherapy-induced degeneration
Hui-wen Liu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
De novo NAD+ synthesis enhances mitochondrial function and improves health
Elena Katsyuba et al.
NATURE (2018)
NAD Metabolism in Cancer Therapeutics
Keisuke Yaku et al.
FRONTIERS IN ONCOLOGY (2018)
Identification of NAD+ capped mRNAs in Saccharomyces cerevisiae
Robert W. Walters et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
NAD and the aging process: Role in life, death and everything in between
Claudia C. S. Chini et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2017)
Kynurenine pathway metabolism and neuroinflammatory disease
Nady Braidy et al.
NEURAL REGENERATION RESEARCH (2017)
The SARM1 Toll/Interleukin-1 Receptor Domain Possesses Intrinsic NAD+ Cleavage Activity that Promotes Pathological Axonal Degeneration
Kow Essuman et al.
NEURON (2017)
Vitamin B3 modulates mitochondrial vulnerability and prevents glaucoma in aged mice
Pete A. Williams et al.
SCIENCE (2017)
Comparison of Sirtuin 3 Levels in ALS and Huntington's Disease-Differential Effects in Human Tissue Samples vs. Transgenic Mouse Models
Eva Buck et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2017)
5′ End Nicotinamide Adenine Dinucleotide Cap in Human Cells Promotes RNA Decay through DXO-Mediated deNADding
Xinfu Jiao et al.
CELL (2017)
NAD+ metabolism: Bioenergetics, signaling and manipulation for therapy
Yue Yang et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2016)
Mitochondrial SIRT3 Mediates Adaptive Responses of Neurons to Exercise and Metabolic and Excitatory Challenges
Aiwu Cheng et al.
CELL METABOLISM (2016)
CD38 Dictates Age-Related NAD Decline and Mitochondrial Dysfunction through an SIRT3-Dependent Mechanism
Juliana Camacho-Pereira et al.
CELL METABOLISM (2016)
NAD+ repletion improves mitochondrial and stem cell function and enhances life span in mice
Hongbo Zhang et al.
SCIENCE (2016)
An Atypical SCF-like Ubiquitin Ligase Complex Promotes Wallerian Degeneration through Regulation of Axonal Nmnat2
Yuya Yamagishi et al.
CELL REPORTS (2016)
NAMPT-Mediated NAD+ Biosynthesis Is Essential for Vision In Mice
Jonathan B. Lin et al.
CELL REPORTS (2016)
NMNAT2:HSP90 Complex Mediates Proteostasis in Proteinopathies
Yousuf O. Ali et al.
PLOS BIOLOGY (2016)
NMNAT1 inhibits axon degeneration via blockade of SARM1-mediated NAD+ depletion
Yo Sasaki et al.
ELIFE (2016)
NAD+ Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus
Carles Canto et al.
CELL METABOLISM (2015)
Reduced Ssy1-Ptr3-Ssy5 (SPS) Signaling Extends Replicative Life Span by Enhancing NAD+ Homeostasis in Saccharomyces cerevisiae
Felicia Tsang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
The yeast Saccharomyces cerevisiae: An overview of methods to study autophagy progression
Elizabeth Delorme-Axford et al.
METHODS (2015)
PARPs and ADP-Ribosylation: 50 Years ... and Counting
W. Lee Kraus
MOLECULAR CELL (2015)
Physiological and pathophysiological roles of NAMPT and NAD metabolism
Antje Garten et al.
NATURE REVIEWS ENDOCRINOLOGY (2015)
Inhibition of nicotinamide phosphoribosyltransferase (NAMPT) as a therapeutic strategy in cancer
Deepak Sampath et al.
PHARMACOLOGY & THERAPEUTICS (2015)
SARM1 activation triggers axon degeneration locally via NAD+ destruction
Josiah Gerdts et al.
SCIENCE (2015)
NAD+ in aging, metabolism, and neurodegeneration
Eric Verdin
SCIENCE (2015)
Oxidative stress and non-SOD1 ALS
Maria Teresa Carri et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2015)
The human NAD metabolome: Functions, metabolism and compartmentalization
Andrey Nikiforov et al.
CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY (2015)
Role of mitochondria in mutant SOD1 linked amyotrophic lateral sclerosis
Wenzhi Tan et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2014)
Activation of SIRT3 by the NAD+ Precursor Nicotinamide Riboside Protects from Noise-Induced Hearing Loss
Kevin D. Brown et al.
CELL METABOLISM (2014)
Regulation of NAD plus metabolism, signaling and compartmentalization in the yeast Saccharomyces cerevisiae
Michiko Kato et al.
DNA REPAIR (2014)
YCL047C/POF1 Is a Novel Nicotinamide Mononucleotide Adenylyltransferase (NMNAT) in Saccharomyces cerevisiae
Michiko Kato et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
NAD+ and sirtuins in aging and disease
Shin-ichiro Imai et al.
TRENDS IN CELL BIOLOGY (2014)
Gcn5 and Sirtuins Regulate Acetylation of the Ribosomal Protein Transcription Factor Ifh1
Michael Downey et al.
CURRENT BIOLOGY (2013)
Secretion of Quinolinic Acid, an Intermediate in the Kynurenine Pathway, for Utilization in NAD+ Biosynthesis in the Yeast Saccharomyces cerevisiae
Kazuto Ohashi et al.
EUKARYOTIC CELL (2013)
Autophagic Processes in Yeast: Mechanism, Machinery and Regulation
Fulvio Reggiori et al.
GENETICS (2013)
NAD+ salvage pathway proteins suppress proteotoxicity in yeast models of neurodegeneration by promoting the clearance of misfolded/oligomerized proteins
Alejandro Ocampo et al.
HUMAN MOLECULAR GENETICS (2013)
The causative role and therapeutic potential of the kynurenine pathway in neurodegenerative disease
Marta Amaral et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2013)
Sarm1-Mediated Axon Degeneration Requires Both SAM and TIR Interactions
Josiah Gerdts et al.
JOURNAL OF NEUROSCIENCE (2013)
Mutant SOD1G93A triggers mitochondrial fragmentation in spinal cord motor neurons: Neuroprotection by SIRT3 and PGC-1α
Wenjun Song et al.
NEUROBIOLOGY OF DISEASE (2013)
Synthetic lethality of PARP and NAMPT inhibition in triple-negative breast cancer cells
Ilirjana Bajrami et al.
EMBO MOLECULAR MEDICINE (2012)
Mutations in NMNAT1 cause Leber congenital amaurosis with early-onset severe macular and optic atrophy
Isabelle Perrault et al.
NATURE GENETICS (2012)
NMNAT1 mutations cause Leber congenital amaurosis
Marni J. Falk et al.
NATURE GENETICS (2012)
Exome sequencing identifies NMNAT1 mutations as a cause of Leber congenital amaurosis
Pei-Wen Chiang et al.
NATURE GENETICS (2012)
Mutations in NMNAT1 cause Leber congenital amaurosis and identify a new disease pathway for retinal degeneration
Robert K. Koenekoop et al.
NATURE GENETICS (2012)
Kynurenines in the mammalian brain: when physiology meets pathology
Robert Schwarcz et al.
NATURE REVIEWS NEUROSCIENCE (2012)
dSarm/Sarm1 Is Required for Activation of an Injury-Induced Axon Death Pathway
Jeannette M. Osterloh et al.
SCIENCE (2012)
Phosphate-responsive Signaling Pathway Is a Novel Component of NAD+ Metabolism in Saccharomyces cerevisiae
Shu-Ping Lu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Regulation of yeast sirtuins by NAD+ metabolism and calorie restriction
Shu-Ping Lu et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2010)
Sirt3 Mediates Reduction of Oxidative Damage and Prevention of Age-Related Hearing Loss under Caloric Restriction
Shinichi Someya et al.
CELL (2010)
Calorie Restriction Reduces Oxidative Stress by SIRT3-Mediated SOD2 Activation
Xiaolei Qiu et al.
CELL METABOLISM (2010)
SIRT3 Deacetylates Mitochondrial 3-Hydroxy-3-Methylglutaryl CoA Synthase 2 and Regulates Ketone Body Production
Tadahiro Shimazu et al.
CELL METABOLISM (2010)
THE ISOLATION AND IDENTIFICATION OF THE ANTI-BLACK TONGUE FACTOR*
C. A. ELVEHJEM et al.
NUTRITION REVIEWS (2010)
The phosphate makes a difference: cellular functions of NADP
Line Agledal et al.
REDOX REPORT (2010)
Protein Acetylation Microarray Reveals that NuA4 Controls Key Metabolic Target Regulating Gluconeogenesis
Yu-yi Lin et al.
CELL (2009)
Identification of Isn1 and Sdt1 as Glucose- and Vitamin-regulated Nicotinamide Mononucleotide and Nicotinic Acid Adenine Dinucleotide 5′-Nucleotidases Responsible for Production of Nicotinamide Riboside and Nicotinic Acid Riboside
Katrina L. Bogan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Assimilation of Endogenous Nicotinamide Riboside Is Essential for Calorie Restriction-mediated Life Span Extension in Saccharomyces cerevisiae
Shu-Ping Lu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
WldS protein requires Nmnat activity and a short N-terminal sequence to protect axons in mice
Laura Conforti et al.
JOURNAL OF CELL BIOLOGY (2009)
Recent progress in the biology and physiology of sirtuins
Toren Finkel et al.
NATURE (2009)
LC/MS analysis of cellular RNA reveals NAD-linked RNA
Y. Grace Chen et al.
NATURE CHEMICAL BIOLOGY (2009)
Quantitation of NAD+ biosynthesis from the salvage pathway in Saccharomyces cerevisiae
Jennifer Sporty et al.
YEAST (2009)
The malate-aspartate NADH shuttle components are novel metabolic longevity regulators required for calorie restriction-mediated life span extension in yeast
Erin Easlon et al.
GENES & DEVELOPMENT (2008)
Saccharomyces cerevisiae YOR071C encodes the high affinity nicotinamide riboside transporter Nrt1
Peter A. Belenky et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Substrates and regulation mechanisms for the human mitochondrial Sirtuins Sirt3 and Sirt5
Christine Schlicker et al.
JOURNAL OF MOLECULAR BIOLOGY (2008)
NAD synthase NMNAT acts as a chaperone to protect against neurodegeneration
R. Grace Zhai et al.
NATURE (2008)
Life span extension by calorie restriction depends on Rim15 and transcription factors downstream of Ras/PKA, Tor, and Sch9
Min Wei et al.
PLOS GENETICS (2008)
A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis
Bong-Hyun Ahn et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Mammalian sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation
David B. Lombard et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
Differences among cell types in NAD+ compartmentalization:: A comparison of neurons, astrocytes, and cardiac myocytes
Conrad C. Alano et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2007)
Nicotinamide riboside kinase structures reveal new pathways to NAD
Wolfram Tempel et al.
PLOS BIOLOGY (2007)
MSN2 and MSN4 link calorie restriction and TOR to sirtuin-mediated lifespan extension in Saccharomyces cerevisiae
Oliver Medvedik et al.
PLOS BIOLOGY (2007)
Nicotinamide riboside promotes Sir2 silencing and extends lifespan via Nrk and Urh1/Pnp1/Meu1 pathways to NAD+
Peter Belenky et al.
CELL (2007)
WldS mice are protected against the Parkinsonian mimetic MPTP
Daphne M. Hasbani et al.
EXPERIMENTAL NEUROLOGY (2006)
Synthetic lethal and biochemical analyses of NAD and NADH kinases in Saccharomyces cerevisiae establish separation of cellular functions
Pawel Bieganowski et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Identification of the mitochondrial NAD+ transporter in Saccharomyces cerevisiae
S Todisco et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Oxidative stress and neurodegeneration: where are we now?
Barry Halliwell
JOURNAL OF NEUROCHEMISTRY (2006)
Rim15 and the crossroads of nutrient signalling pathways in Saccharomyces cerevisiae
Erwin Swinnen et al.
CELL DIVISION (2006)
Impairing the bioenergetic status and the biogenesis of mitochondria triggers mitophagy in yeast
M Priault et al.
CELL DEATH AND DIFFERENTIATION (2005)
Identification of ATP-NADH kinase isozymes and their contribution to supply of NADP(H) in Saccharomyces cerevisiae
F Shi et al.
FEBS JOURNAL (2005)
Regulation of NAD synthesis by the trifunctional NadR protein of Salmonella enterica
JH Grose et al.
JOURNAL OF BACTERIOLOGY (2005)
Mechanism of sirtuin inhibition by nicotinamide:: Altering the NAD+ cosubstrate specificity of a Sir2 enzyme
JL Avalos et al.
MOLECULAR CELL (2005)
Poly(ADP-ribosyl)ation by PARP-1: 'PAR-laying' NAD(+) into a nuclear signal
MY Kim et al.
GENES & DEVELOPMENT (2005)
Nicotinamide clearance by Pnc1 directly regulates Sir2-mediated silencing and longevity
CA Gallo et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Calorie restriction extends yeast life span by lowering the level of NADH
SJ Lin et al.
GENES & DEVELOPMENT (2004)
Pellagra: Dermatitis, dementia, and diarrhea
J Hegyi et al.
INTERNATIONAL JOURNAL OF DERMATOLOGY (2004)
Discoveries of nicotinamide riboside as a nutrient and conserved NRK genes establish a Preiss-Handler independent route to NAD+ in fungi and humans
P Bieganowski et al.
CELL (2004)
Neurodegenerative diseases and oxidative stress
J Emerit et al.
BIOMEDICINE & PHARMACOTHERAPY (2004)
Mechanism of nicotinamide inhibition and transglycosidation by Sir2 histone/protein deacetylases
MD Jackson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
NAD+-dependent deacetylase Hst1p controls biosynthesis and cellular NAD+ levels in Saccharomyces cerevisiae
A Bedalov et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Eukaryotic NAD+ synthetase Qns1 contains an essential, obligate intramolecular thiol glutamine amidotransferase domain related to nitrilase
P Bieganowski et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
POS5 gene of Saccharomyces cerevisiae encodes a mitochondrial NADH kinase required for stability of mitochondrial DNA
MK Strand et al.
EUKARYOTIC CELL (2003)
Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae
RM Anderson et al.
NATURE (2003)
A history of research on yeasts 5: the fermentation pathway
JA Barnett
YEAST (2003)
Identification and characterization of a second NMN adenylyltransferase gene in Saccharomyces cerevisiae
M Emanuelli et al.
PROTEIN EXPRESSION AND PURIFICATION (2003)
Nicotinamide offers multiple protective mechanisms in stroke as a precursor for NAD(+), as a PARP inhibitor and by partial restoration of mitochondrial function
L Klaidman et al.
PHARMACOLOGY (2003)
Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast Sir2 and human SIRT1
KJ Bitterman et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Manipulation of a nuclear NAD+ salvage pathway delays aging without altering steady-state NAD+ levels
RM Anderson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Aerobic and anaerobic NAD+ metabolism in Saccharomyes cerevisiae
C Panozzo et al.
FEBS LETTERS (2002)
Identification and functional analysis of the Saccharomyces cerevisiae nicotinamidase gene, PNC1
M Ghislain et al.
YEAST (2002)
Nicotinamide modulates mitochondrial membrane potential and cysteine protease activity during cerebral vascular endothelial cell injury
ZZ Chong et al.
JOURNAL OF VASCULAR RESEARCH (2002)
Wallerian degeneration of injured axons and synapses is delayed by a Ube4b/Nmnat chimeric gene
TGA Mack et al.
NATURE NEUROSCIENCE (2001)
Chemical inhibition of the Pho85 cyclin-dependent kinase reveals a role in the environmental stress response
AS Carroll et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Antioxidant function of cytosolic sources of NADPH in yeast
KL Minard et al.
FREE RADICAL BIOLOGY AND MEDICINE (2001)
Common themes in mechanisms of gene silencing
D Moazed
MOLECULAR CELL (2001)
The NADH diphosphatase encoded by the Saccharomyces cerevisiae NYP1 nudix hydrolase gene is located in peroxisomes
SR AbdelRaheim et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2001)
Oxidative damage linked to neurodegeneration by selective α-synuclein nitration in synucleinopathy lesions
BI Giasson et al.
SCIENCE (2000)
Identification of the copper regulon in Saccharomyces cerevisiae by DNA microarrays
C Gross et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae
SJ Lin et al.
SCIENCE (2000)
The mitochondrial alcohol dehydrogenase adh3p is involved in a redox shuttle in Saccharomyces cerevisiae
BM Bakker et al.
JOURNAL OF BACTERIOLOGY (2000)
Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins
RA Frye
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2000)
Transcriptional regulation of the Saccharomyces cerevisiae DAL5 gene family and identification of the high affinity nicotinic acid permease TNA1 (YGR260w)
B Llorente et al.
FEBS LETTERS (2000)
A phylogenetically conserved NAD+-dependent protein deacetylase activity in the Sir2 protein family
JS Smith et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
The silencing protein SIR2 and its homologs are MAD-dependent protein deacetylases
J Landry et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
分享论文
