期刊
CARBOHYDRATE POLYMERS
卷 144, 期 -, 页码 106-114出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.carbpol.2016.02.030
关键词
Psidium guajava Linn.; Guava; Polysaccharides; Structure; alpha-Glucosidase inhibition activity; DPPH center dot scavenging activity
资金
- National Natural Science Foundation of China [81102779]
- Guangdong Natural Science Foundation [9451022401003453]
- Pearl River S&T Nova Program of Guangzhou [2013J2200035]
- Innovation Program of the University of Guangdong Province [2014KTSCX118]
- Science and Technology Program of Guangdong Province [2014A050503067, 2015A020211032]
- High-level Talents Program of the University of Guangdong Province
To explore the chemicals responsible for the health benefits of guava, water-soluble polysaccharides were extracted including GP90 and P90. They exhibited excellent alpha-glucosidase inhibition activity with an EC50 of 2.27 mu g/mL and 0.18 mg/mL. This suggests that their activities were 1379- and 17-fold higher than the positive control. The DPPH center dot scavenging activities of GP90 was even higher than Vc at some concentrations. Upon further isolation, a novel polysaccharide termed GB90-1B was obtained. Monosaccharide analysis, methylation analysis, and NMR were used to analyze the structural characterization of GB90-1B. Structural analysis revealed that its backbone consisted of (1 -> 5)-linked-alpha-L-arabinose, (1 -> 2,3,5)-linked-alpha-L-arabinose and (1 -> 3)-linked-alpha-L-arabinose. Branch linkages included( 1 -> 6)-linked-alpha-D-glucose, (1 ->)-linked-alpha-D-glucose and (1 ->)-linked-alpha-L-arabinose. The structure of the repeating unit of GP90-1B was predicted. (C) 2016 Elsevier Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据