期刊
CARBOHYDRATE POLYMERS
卷 144, 期 -, 页码 438-446出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.carbpol.2016.02.073
关键词
Polysaccharides; Bamboo shoot shells; Structural characterization; Hypoglycemic activity
The bamboo shoot (Leleba oldhami Nakal) shell is a by-product during bamboo shoot processing. It is a cheap and available resource for dietary polysaccharides. Herein, a novel polysaccharide BSSP2a was isolated and characterized from the bamboo shoot shell polysaccharides, and it was identified as a homogeneous highly-branched beta type pyran polysaccharide with a molecular weight of 1.63 x 10(4) kDa, which consisted of arabinose, xylose, mannose, glucose and galactose at a molar ratio of 20.4: 4.9: 1: 3.4: 20.6. The crude polysaccharides (BSSP) from the bamboo shoots shell showed hypoglycemic activity on the high fat diet and streptozotocin induced diabetic mice in a dose-dependent manner. The administration of high dose BSSP (400 mg/kg) improved body weight loss and serum insulin loss, and significantly decreased the blood glucose level, serum triglycerides as well as total cholesterol levels by 48.7%, 34.8% and 26.5%, respectively. The results highlight the potential of the bamboo shoot shell polysaccharides as a natural anti-diabetic agent. (C) 2016 Elsevier Ltd. All rights reserved.
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