相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Extracellular Hsp70 Reduces the Pro-Tumor Capacity of Monocytes/Macrophages Co-Cultivated with Cancer Cells
Elena Y. Komarova et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Targeting the interaction of AIMP2-DX2 with HSP70 suppresses cancer development
Semi Lim et al.
NATURE CHEMICAL BIOLOGY (2020)
Structural Basis of TLR2/TLR1 Activation by the Synthetic Agonist Diprovocim
Lijing Su et al.
JOURNAL OF MEDICINAL CHEMISTRY (2019)
Radiochemotherapy combined with NK cell transfer followed by second-line PD-1 inhibition in apatient with NSCLC stage IIIb inducing long-term tumor control: acase study
Konrad Kokowski et al.
STRAHLENTHERAPIE UND ONKOLOGIE (2019)
HSP70 is a negative regulator of NLRP3 inflammasome activation
Pierre Martine et al.
CELL DEATH & DISEASE (2019)
Hsp70-and Hsp90-Mediated Regulation of the Conformation of p53 DNA Binding Domain and p53 Cancer Variants
Marta Boysen et al.
MOLECULAR CELL (2019)
Coordinated Conformational Processing of the Tumor Suppressor Protein p53 by the Hsp70 and Hsp90 Chaperone Machineries
Vinay Dahiya et al.
MOLECULAR CELL (2019)
Hsp70 interactions with membrane lipids regulate cellular functions in health and disease
Zsolt Balogi et al.
PROGRESS IN LIPID RESEARCH (2019)
Increased heat shock protein 70 (Hsp70) serum levels and low NK cell counts after radiotherapy - potential markers for predicting breast cancer recurrence?
Anna Rothammer et al.
RADIATION ONCOLOGY (2019)
Design, Synthesis, Evaluation, and Structural Studies of C2-Symmetric Small Molecule Inhibitors of Programmed Cell Death1/Programmed Death-Ligand 1 Protein-Protein Interaction
Subhadwip Basu et al.
JOURNAL OF MEDICINAL CHEMISTRY (2019)
Structural mechanism for NEK7-licensed activation of NLRP3 inflammasome
Humayun Sharif et al.
NATURE (2019)
Specificity for latent C termini links the E3 ubiquitin ligase CHIP to caspases
Matthew Ravalin et al.
NATURE CHEMICAL BIOLOGY (2019)
The Hsp70 chaperone network
Rina Rosenzweig et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2019)
Structural basis of assembly of the human T cell receptor-CD3 complex
De Dong et al.
NATURE (2019)
Structural basis for client recognition and activity of Hsp40 chaperones
Yajun Jiang et al.
SCIENCE (2019)
Hsp70 (HSP70A1A) downregulation enhances the metastatic ability of cancer cells
Panagiota Kasioumi et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2019)
Tissue necrosis and its role in cancer progression
Adi Karsch-Bluman et al.
ONCOGENE (2019)
Phase II open label trial of minnelide™ in patients with chemotherapy refractory metastatic pancreatic cancer
David Propper et al.
CANCER RESEARCH (2019)
CD40/anti-CD40 antibody complexes which illustrate agonist and antagonist structural switches
Maria A. Argiriadi et al.
BMC MOLECULAR AND CELL BIOLOGY (2019)
Membrane heat shock protein 70: a theranostic target for cancer therapy
Maxim Shevtsov et al.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2018)
Acute HSF1 depletion induces cellular senescence through the MDM2-p53-p21 pathway in human diploid fibroblasts
Tsukasa Oda et al.
JOURNAL OF CELL SCIENCE (2018)
Substrate Binding Switches the Conformation at the Lynchpin Site in the Substrate-Binding Domain of Human Hsp70 to Enable Allosteric Interdomain Communication
Kohei Umehara et al.
MOLECULES (2018)
Immune modulatory effects of radiotherapy as basis for well-reasoned radioimmunotherapies
Michael Rueckert et al.
STRAHLENTHERAPIE UND ONKOLOGIE (2018)
Cancer cell responses to Hsp70 inhibitor JG-98: Comparison with Hsp90 inhibitors and finding synergistic drug combinations
Julia A. Yaglom et al.
SCIENTIFIC REPORTS (2018)
Hsp90 Mediates Membrane Deformation and Exosome Release
Elsa Lauwers et al.
MOLECULAR CELL (2018)
Role of the NLRP3 inflammasome in cancer
Maryam Moossavi et al.
MOLECULAR CANCER (2018)
Heat Shock Proteins as Immunomodulants
Tawanda Zininga et al.
MOLECULES (2018)
Membrane Hsp70 -A Novel Target for the Isolation of Circulating Tumor Cells After Epithelial-to-Mesenchymal Transition
Stephanie Breuninger et al.
FRONTIERS IN ONCOLOGY (2018)
Subcellular Hsp70 Inhibitors Promote Cancer Cell Death via Different Mechanisms
Sang-Hyun Park et al.
CELL CHEMICAL BIOLOGY (2018)
The HSP90 chaperone machinery
Florian H. Schopf et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2017)
HSP70-1 is required for interleukin-5-induced angiogenic responses through eNOS pathway
Sung Lyea Park et al.
SCIENTIFIC REPORTS (2017)
Molecular Chaperone Accumulation in Cancer and Decrease in Alzheimer's Disease: The Potential Roles of HSF1
Stuart K. Calderwood et al.
FRONTIERS IN NEUROSCIENCE (2017)
Dynamics of Heat Shock Protein 70 Serum Levels As a Predictor of Clinical Response in Non-Small-Cell Lung Cancer and Correlation with the Hypoxia-Related Marker Osteopontin
Christian Ostheimer et al.
FRONTIERS IN IMMUNOLOGY (2017)
Extracellular HSP70 Activates ERK1/2, NF-κB and Pro-Inflammatory Gene Transcription Through Binding with RAGE in A549 Human Lung Cancer Cells
Nauana Somensi et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2017)
MET: roles in epithelial-mesenchymal transition and cancer stemness
Hye-Min Jeon et al.
ANNALS OF TRANSLATIONAL MEDICINE (2017)
Heat shock protein 70-1A is a novel angiogenic regulator
Taek-Keun Kim et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2016)
The Tag7-Hsp70 cytotoxic complex induces tumor cell necroptosis via permeabilisation of lysosomes and mitochondria
Denis V. Yashin et al.
BIOCHIMIE (2016)
Regulators of complement activity mediate inhibitory mechanisms through a common C3b-binding mode
Federico Forneris et al.
EMBO JOURNAL (2016)
Exploiting Protein Conformational Change to Optimize Adenosine-Derived Inhibitors of HSP70
Matthew D. Cheeseman et al.
JOURNAL OF MEDICINAL CHEMISTRY (2016)
The epichaperome is an integrated chaperome network that facilitates tumour survival
Anna Rodina et al.
NATURE (2016)
A novel Hsp70 inhibitor prevents cell intoxication with the actin ADP-ribosylating Clostridium perfringens iota toxin
Katharina Ernst et al.
SCIENTIFIC REPORTS (2016)
A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms
Alan M. Jones et al.
SCIENTIFIC REPORTS (2016)
A near atomic structure of the active human apoptosome
Tat Cheung Cheng et al.
ELIFE (2016)
Influence of In Vitro IL-2 or IL-15 Alone or in Combination with Hsp 70 Derived 14-Mer Peptide (TKD) on the Expression of NK Cell Activatory and Inhibitory Receptors on Peripheral Blood T Cells, B Cells and NKT Cells
Ilona Hromadnikova et al.
PLOS ONE (2016)
The Role of the Membrane-Initiated Heat Shock Response in Cancer
Zohar Bromberg et al.
FRONTIERS IN MOLECULAR BIOSCIENCES (2016)
Dendritic cells transfected with heat-shock protein 70 messenger RNA for patients with hepatitis C virus-related hepatocellular carcinoma: a phase 1 dose escalation clinical trial
Yoshinari Maeda et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2015)
A Small Molecule Inhibitor of ATPase Activity of HSP70 Induces Apoptosis and Has Antitumor Activities
Sung-Kyun Ko et al.
CHEMISTRY & BIOLOGY (2015)
The Novolactone Natural Product Disrupts the Allosteric Regulation of Hsp70
A. Quamrul Hassan et al.
CHEMISTRY & BIOLOGY (2015)
Validation of the Hsp70-Bag3 Protein-Protein Interaction as a Potential Therapeutic Target in Cancer
Xiaokai Li et al.
MOLECULAR CANCER THERAPEUTICS (2015)
Role of membrane Hsp70 in radiation sensitivity of tumor cells
Naoya Murakami et al.
RADIATION ONCOLOGY (2015)
A Bipartite Interaction between Hsp70 and CHIP Regulates Ubiquitination of Chaperoned Client Proteins
Huaqun Zhang et al.
STRUCTURE (2015)
Correlation of Hsp70 serum levels with gross tumor volume and composition of lymphocyte subpopulations in patients with squamous cell and adeno non-small cell lung cancer
Sophie Gunther et al.
FRONTIERS IN IMMUNOLOGY (2015)
Heat shock protein 70 (Hsp70) peptide activated Natural Killer (NK) cells for the treatment of patients with non-small cell lung cancer (NSCLC) after radiochemotherapy (RCTx) - from preclinical studies to a clinical phase II trial
Hanno M. Specht et al.
FRONTIERS IN IMMUNOLOGY (2015)
Implications of the hybrid epithelial/mesenchymal phenotype in metastasis
Mohit Kumar Jolly et al.
FRONTIERS IN ONCOLOGY (2015)
Hsp70 in cancer: back to the future
M. Y. Sherman et al.
ONCOGENE (2015)
The nucleotide exchange factors of Hsp70 molecular chaperones
Andreas Bracher et al.
FRONTIERS IN MOLECULAR BIOSCIENCES (2015)
Hsp70-Bag3 Interactions Regulate Cancer-Related Signaling Networks
Teresa A. Colvin et al.
CANCER RESEARCH (2014)
Identification of an Allosteric Small-Molecule Inhibitor Selective for the Inducible Form of Heat Shock Protein 70
Matthew K. Howe et al.
CHEMISTRY & BIOLOGY (2014)
Increased expression of stress inducible protein 1 in glioma-associated microglia/macrophages
Anna Carolina Carvalho da Fonseca et al.
JOURNAL OF NEUROIMMUNOLOGY (2014)
HSP70 inhibits high glucose-induced Smad3 activation and attenuates epithelial-to-mesenchymal transition of peritoneal mesothelial cells
Jun Liu et al.
MOLECULAR MEDICINE REPORTS (2014)
Crystal Structure of the Stress-Inducible Human Heat Shock Protein 70 Substrate-Binding Domain in Complex with Peptide Substrate
Pingfeng Zhang et al.
PLOS ONE (2014)
Knockdown of Hop downregulates RhoC expression, and decreases pseudopodia formation and migration in cancer cell lines
Tarryn Willmer et al.
CANCER LETTERS (2013)
Minnelide reduces tumor burden in preclinical models of osteosarcoma
Sulagna Banerjee et al.
CANCER LETTERS (2013)
Identification of an Allosteric Pocket on Human Hsp70 Reveals a Mode of Inhibition of This Therapeutically Important Protein
Anna Rodina et al.
CHEMISTRY & BIOLOGY (2013)
Lysosomal Rerouting of Hsp70 Trafficking as a Potential Immune Activating Tool for Targeting Melanoma
Kata Juhasz et al.
CURRENT PHARMACEUTICAL DESIGN (2013)
The Therapeutic Target Hsp90 and Cancer Hallmarks
Yoshihiko Miyata et al.
CURRENT PHARMACEUTICAL DESIGN (2013)
Intracellular and extracellular Hsp70 chaperone as a target for cancer therapy
Irina V. Guzhova et al.
INTERNATIONAL JOURNAL OF HYPERTHERMIA (2013)
Triptolide Induces the Expression of miR-142-3p: A Negative Regulator of Heat Shock Protein 70 and Pancreatic Cancer Cell Proliferation
Tiffany N. MacKenzie et al.
MOLECULAR CANCER THERAPEUTICS (2013)
Activation of Hsp70 reduces neurotoxicity by promoting polyglutamine protein degradation
Adrienne M. Wang et al.
NATURE CHEMICAL BIOLOGY (2013)
Structure and function of Hip, an attenuator of the Hsp70 chaperone cycle
Zhuo Li et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2013)
Tumor Stress-Induced Phosphoprotein1 (STIP1) as a Prognostic Biomarker in Ovarian Cancer
Angel Chao et al.
PLOS ONE (2013)
Disruption of Hydrogen Bonds between Major Histocompatibility Complex Class II and the Peptide N-Terminus Is Not Sufficient to Form a Human Leukocyte Antigen-DM Receptive State of Major Histocompatibility Complex Class II
Monika-Sarah E. D. Schulze et al.
PLOS ONE (2013)
Minnelide: A Novel Therapeutic That Promotes Apoptosis in Non-Small Cell Lung Carcinoma In Vivo
Ilona Rousalova et al.
PLOS ONE (2013)
Extracellular HSP70/HSP70-PCs Promote EpithelialMesenchymal Transition of Hepatocarcinoma Cells
Hangyu Li et al.
PLOS ONE (2013)
Hsp70 promotes chemoresistance by blocking Bax mitochondrial translocation in ovarian cancer cells
Xiaokui Yang et al.
CANCER LETTERS (2012)
MMP-9 induces CD44 cleavage and CD44 mediated cell migration in glioblastoma xenograft cells
Chandramu Chetty et al.
CELLULAR SIGNALLING (2012)
Hsp90 Molecular Chaperone Inhibitors: Are We There Yet?
Len Neckers et al.
CLINICAL CANCER RESEARCH (2012)
Demethoxycurcumin Modulates Prostate Cancer Cell Proliferation via AMPK-Induced Down-regulation of HSP70 and EGFR
Chao-Ming Hung et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2012)
The C-terminal Helices of Heat Shock Protein 70 Are Essential for J-domain Binding and ATPase Activation
Xue-Chao Gao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
HSP90 and HSP70 Proteins Are Essential for Stabilization and Activation of WASF3 Metastasis-promoting Protein
Yong Teng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Heat Shock Transcription Factor Hsf1 Is Involved in Tumor Progression via Regulation of Hypoxia-Inducible Factor 1 and RNA-Binding Protein HuR
Vladimir L. Gabai et al.
MOLECULAR AND CELLULAR BIOLOGY (2012)
Correction: Rhodacyanine Derivative Selectively Targets Cancer Cells and Overcomes Tamoxifen Resistance
John Koren et al.
PLoS One (2012)
HSP70 Enhances Immunosuppressive Function of CD4+CD25+FoxP3+ T Regulatory Cells and Cytotoxicity in CD4+CD25- T Cells
Julian Wachstein et al.
PLOS ONE (2012)
Myricetin induces pancreatic cancer cell death via the induction of apoptosis and inhibition of the phosphatidylinositol 3-kinase (PI3K) signaling pathway
P. A. Phillips et al.
CANCER LETTERS (2011)
BAG3 (BCL2-associated athanogene 3) interacts with MMP-2 to positively regulate invasion by ovarian carcinoma cells
Miwa Suzuki et al.
CANCER LETTERS (2011)
RNAi knockdown of Hop (Hsp70/Hsp90 organising protein) decreases invasion via MMP-2 down regulation
Naomi Walsh et al.
CANCER LETTERS (2011)
Peptides and Aptamers Targeting HSP70: A Novel Approach for Anticancer Chemotherapy
Anne-Laure Rerole et al.
CANCER RESEARCH (2011)
Hallmarks of Cancer: The Next Generation
Douglas Hanahan et al.
CELL (2011)
Triptolide and its expanding multiple pharmacological functions
Qiuyan Liu
INTERNATIONAL IMMUNOPHARMACOLOGY (2011)
Crystallographic and Mutational Analysis of the CD40-CD154 Complex and Its Implications for Receptor Activation
Hyun-Jung An et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
HSP70 decreases receptor-dependent phosphorylation of Smad2 and blocks TGF-β-induced epithelial-mesenchymal transition
Yihao Li et al.
JOURNAL OF GENETICS AND GENOMICS (2011)
Adenosine-Derived Inhibitors of 78 kDa Glucose Regulated Protein (Grp78) ATPase: Insights into Isoform Selectivity
Alba T. Macias et al.
JOURNAL OF MEDICINAL CHEMISTRY (2011)
Allosteric Drugs: The Interaction of Antitumor Compound MKT-077 with Human Hsp70 Chaperones
Aikaterini Rousaki et al.
JOURNAL OF MOLECULAR BIOLOGY (2011)
The C-terminus of Hsp70-Interacting Protein Promotes Met Receptor Degradation
Kang Won Jang et al.
JOURNAL OF THORACIC ONCOLOGY (2011)
Heat shock protein Hsp72 plays an essential role in Her2-induced mammary tumorigenesis
L. Meng et al.
ONCOGENE (2011)
Accelerating Protein Docking in ZDOCK Using an Advanced 3D Convolution Library
Brian G. Pierce et al.
PLOS ONE (2011)
Targeting membrane heat-shock protein 70 (Hsp70) on tumors by cmHsp70.1 antibody
Stefan Stangl et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Chemical methodology as a source of small-molecule checkpoint inhibitors and heat shock protein 70 (Hsp70) modulators
Donna M. Huryn et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Biochemical and structural studies on the high affinity of Hsp70 for ADP
Akihiko Arakawa et al.
PROTEIN SCIENCE (2011)
Antimyeloma Effects of the Heat Shock Protein 70 Molecular Chaperone Inhibitor MAL3-101
Marc J. Braunstein et al.
JOURNAL OF ONCOLOGY (2011)
Direct inter-subdomain interactions switch between the closed and open forms of the Hsp70 nucleotide-binding domain in the nucleotide-free state
Meiri Shida et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2010)
Heat shock protein 70 together with its co-chaperone CHIP inhibits TNF-α induced apoptosis by promoting proteasomal degradation of apoptosis signal-regulating kinase1
Yanhong Gao et al.
APOPTOSIS (2010)
Geldanamycin inhibits TGF-β signaling through induction of Hsp70
Chang-Hyun Yun et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2010)
Peptide-Binding Sites As Revealed by the Crystal Structures of the Human Hsp40 Hdj1 C-Terminal Domain in Complex with the Octapeptide from Human Hsp70
Hironori Suzuki et al.
BIOCHEMISTRY (2010)
Inactivation of the WASF3 gene in prostate cancer cells leads to suppression of tumorigenicity and metastases
Y. Teng et al.
BRITISH JOURNAL OF CANCER (2010)
A novel, small molecule inhibitor of Hsc70/Hsp70 potentiates Hsp90 inhibitor induced apoptosis in HCT116 colon carcinoma cells
Andrew J. Massey et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2010)
CHIP participates in protein triage decisions by preferentially ubiquitinating Hsp70-bound substrates
Marta Stankiewicz et al.
FEBS JOURNAL (2010)
N-domain of human adhesion/growth-regulatory galectin-9: Preference for distinct conformers and non-sialylated N-glycans and detection of ligand-induced structural changes in crystal and solution
Dolores Solis et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2010)
X-ray Structures of Human Galectin-9 C-terminal Domain in Complexes with a Biantennary Oligosaccharide and Sialyllactose
Hiromi Yoshida et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Quercetin Suppresses HeLa Cell Viability via AMPK-Induced HSP70 and EGFR Down-Regulation
Jin Hee Jung et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2010)
Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells
Fanny Chalmin et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Role of Hsp-70 in Triptolide-Mediated Cell Death of Neuroblastoma
Mara B. Antonoff et al.
JOURNAL OF SURGICAL RESEARCH (2010)
`The HSP70 chaperone machinery: J proteins as drivers of functional specificity
Harm H. Kampinga et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
Structure of the measles virus hemagglutinin bound to the CD46 receptor
Cesar Santiago et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2010)
Heat-shock transcription factor HSF1 has a critical role in human epidermal growth factor receptor-2-induced cellular transformation and tumorigenesis
L. Meng et al.
ONCOGENE (2010)
The C-Terminal BAG Domain of BAG5 Induces Conformational Changes of the Hsp70 Nucleotide-Binding Domain for ADP-ATP Exchange
Akihiko Arakawa et al.
STRUCTURE (2010)
Tetrahydroisoquinoline amide substituted phenyl pyrazoles as selective Bcl-2 inhibitors
John Porter et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2009)
Computational analysis of the human HSPH/HSPA/DNAJ family and cloning of a human HSPH/HSPA/DNAJ expression library
Jurre Hageman et al.
CELL STRESS & CHAPERONES (2009)
Multi-faceted role of HSP40 in cancer
Aparna Mitra et al.
CLINICAL & EXPERIMENTAL METASTASIS (2009)
A Phase I Trial of a Human Papillomavirus DNA Vaccine for HPV16+ Cervical Intraepithelial Neoplasia 2/3
Cornelia L. Trimble et al.
CLINICAL CANCER RESEARCH (2009)
A phase I trial of intratumoral administration of recombinant oncolytic adenovirus overexpressing HSP70 in advanced solid tumor patients
J-L Li et al.
GENE THERAPY (2009)
Novel Adenosine-Derived Inhibitors of 70 kDa Heat Shock Protein, Discovered Through Structure-Based Design
Douglas S. Williamson et al.
JOURNAL OF MEDICINAL CHEMISTRY (2009)
Anti-tumor activity of patient-derived NK cells after cell-based immunotherapy - a case report
Valeria Milani et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2009)
Heat Shock Protein Hsp72 Controls Oncogene-Induced Senescence Pathways in Cancer Cells
Vladimir L. Gabai et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
A Small Molecule Inhibitor of Inducible Heat Shock Protein 70
J. I-Ju Leu et al.
MOLECULAR CELL (2009)
The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex
Beom Seok Park et al.
NATURE (2009)
An apoptosis-inducing small molecule that binds to heat shock protein 70
Darren R. Williams et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2008)
Influence of Hsp70 and HLA-E on the killing of leukemic blasts by cytokine/Hsp70 peptide-activated human natural killer (NK) cells
Stefan Stangl et al.
CELL STRESS & CHAPERONES (2008)
Hsp70 translocates into the plasma membrane after stress and is released into the extracellular environment in a membrane-associated form that activates macrophages
Virginia L. Vega et al.
JOURNAL OF IMMUNOLOGY (2008)
JNK signaling in apoptosis
D. N. Dhanasekaran et al.
ONCOGENE (2008)
Tumor-Specific Hsp70 Plasma Membrane Localization Is Enabled by the Glycosphingolipid Gb3
Mathias Gehrmann et al.
PLOS ONE (2008)
AIMP2/p38, the scaffold for the multi-tRNA synthetase complex, responds to genotoxic stresses via p53
Jung Min Han et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
HSP72 attenuates renal tubular cell apoptosis and interstitial fibrosis in obstructive nephropathy
Haiping Mao et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2008)
The heterodimeric assembly of the CD94-NKG2 receptor family and implications for human leukocyte antigen-E recognition
Lucy C. Sullivan et al.
IMMUNITY (2007)
Mechanisms for Hsp70 secretion: Crossing membranes without a leader
Salarnatu S. Marnbula et al.
METHODS (2007)
Triptolide induces pancreatic cancer cell death via inhibition of heat shock protein 70
Phoebe A. Phillips et al.
CANCER RESEARCH (2007)
Patient survival by Hsp70 membrane phenotype - Association with different routes of metastasis
Karin Pfister et al.
CANCER (2007)
The heat shock protein 70 family:: Highly homologous proteins with overlapping and distinct functions
Mads Daugaard et al.
FEBS LETTERS (2007)
Mortalin sensitizes human cancer cells to MKT-077-induced senescence
Custer C. Deocaris et al.
CANCER LETTERS (2007)
Down-regulation of WAVE3, a metastasis promoter gene, inhibits invasion and metastasis of breast cancer cells
Khalid Sossey-Alaoui et al.
AMERICAN JOURNAL OF PATHOLOGY (2007)
ZRANK: Reranking protein docking predictions with an optimized energy function
Brian Pierce et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2007)
Lens epithelium-derived growth factor is an Hsp70-2 regulated guardian of lysosomal stability in human cancer
Mads Daugaard et al.
CANCER RESEARCH (2007)
High levels of heat shock protein Hsp72 in cancer cells suppress default senescence pathways
Julia A. Yaglom et al.
CANCER RESEARCH (2007)
Hsp70 protects against UVB induced apoptosis by preventing release of cathepsins and cytochrome c in human melanocytes
Cecilia Bivik et al.
CARCINOGENESIS (2007)
Hypoxia-inducible factors: central regulators of the tumor phenotype
John D. Gordan et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2007)
Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor
Lu Deng et al.
NATURE IMMUNOLOGY (2007)
Release of heat shock protein 70 (Hsp70) and the effects of extracellular Hsp70 on matric metal loproteinase-9 expression in human monocytic U937 cells
Kyoung-Jin Lee et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2006)
Heat shock protein 70 neutralization exerts potent antitumor effects in animal models of colon cancer and melanoma
E Schmitt et al.
CANCER RESEARCH (2006)
Heat shock proteins in cancer: chaperones of tumorigenesis
SK Calderwood et al.
TRENDS IN BIOCHEMICAL SCIENCES (2006)
Hsp70 inhibits heat-induced apoptosis upstream of mitochondria by preventing Bax translocation
AR Stankiewicz et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Alternative mechanism by which IFN-γ enhances tumor recognition:: Active release of heat shock protein 72
MA Bausero et al.
JOURNAL OF IMMUNOLOGY (2005)
Induction of heat shock proteins in B-cell exosomes
A Clayton et al.
JOURNAL OF CELL SCIENCE (2005)
Using a xenograft model of human breast cancer metastasis to find genes associated with clinically aggressive disease
HM Kluger et al.
CANCER RESEARCH (2005)
Exosome-dependent trafficking of HSP70 - A novel secretory pathway for cellular stress proteins
GI Lancaster et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Heat shock protein 70 surface-positive tumor exosomes stimulate migratory and cytolytic activity of natural killer cells
R Gastpar et al.
CANCER RESEARCH (2005)
Combination of imatinib mesylate with autologous leukocyte-derived heat shock protein and chronic myelogenous leukemia
ZH Li et al.
CLINICAL CANCER RESEARCH (2005)
WAVE3-mediated cell migration and lamellipodia formation are regulated downstream of phosphatidylinositol 3-kinase
K Sossey-Alaoui et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Heat shock proteins in cancer: diagnostic, prognostic, predictive, and treatment implications
DR Ciocca et al.
CELL STRESS & CHAPERONES (2005)
Extracellular HSP70 binding to surface receptors present on antigen presenting cells and endothelial/epithelial cells
JR Thériault et al.
FEBS LETTERS (2005)
Hsp70 chaperones: Cellular functions and molecular mechanism
MP Mayer et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2005)
Crystal structure of a soluble CD28-Fab complex
EJ Evans et al.
NATURE IMMUNOLOGY (2005)
Mechanistic role of heat shock protein 70 in Bcr-Abl-mediated resistance to apoptosis in human acute leukemia cells
F Guo et al.
BLOOD (2005)
Molecular chaperones and the stress of oncogenesis
DD Mosser et al.
ONCOGENE (2004)
PI3K/Akt is required for heat shock proteins to protect hypoxia-inducible factor 1α from pVHL-independent degradation
J Zhou et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Peptidoglycan recognition protein Tag7 forms a cytotoxic complex with heat shock protein 70 in solution and in lymphocytes
LP Sashchenko et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
A simple method to cure established tumors by inflammatory killing of normal cells
GA Daniels et al.
NATURE BIOTECHNOLOGY (2004)
Heat shock protein 70 promotes cell survival by inhibiting lysosomal membrane permeabilization
J Nylandsted et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2004)
Small molecule modulators of endogenous and co-chaperone-stimulated Hsp70 ATPase activity
SW Fewell et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Hsc70 and Hsp70 interact with phosphatidylserine on the surface of PC12 cells resulting in a decrease of viability
N Arispe et al.
FASEB JOURNAL (2004)
Treatment of colon and lung cancer patients with ex vivo heat shock protein 70-peptide-activated, autologous natural killer cells:: a clinical phase I trial
SW Krause et al.
CLINICAL CANCER RESEARCH (2004)
Growth-regulatory human galectin-1:: Crystallographic characterisation of the structural changes induced by single-site mutations and their impact on the thermodynamics of ligand binding
MF López-Lucendo et al.
JOURNAL OF MOLECULAR BIOLOGY (2004)
Regulation of necrosis of H9c2 myogenic cells upon transient energy deprivation - Rapid deenergization of mitochondria precedes necrosis and is controlled by reactive oxygen species, stress kinase JNK, Hsp72, and ARC
JA Yaglom et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Role of the RNA-binding protein HuR in colon carcinogenesis
IL de Silanes et al.
ONCOGENE (2003)
Hypoxia-inducible factor and its biomedical relevance
LE Huang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
hsp72 inhibits focal adhesion kinase degradation in ATP-depleted renal epithelial cells
HP Mao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Symmetry recognizing asymmetry: Analysis of the interactions between the C-type lectin-like immunoreceptor NKG2D and MHC class I-like ligands
BJ McFarland et al.
STRUCTURE (2003)
Heat shock protein 70 membrane expression and melanoma-associated marker phenotype in primary and metastatic melanoma
B Farkas et al.
MELANOMA RESEARCH (2003)
Crystal structure of the receptor-binding domain of human B7-2: Insights into organization and signaling
XW Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Global profiling of the cell surface proteome of cancer cells uncovers an abundance of proteins with chaperone function
BK Shin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Interaction of heat shock protein 70 peptide with NK cells involves the NK receptor CD94
C Gross et al.
BIOLOGICAL CHEMISTRY (2003)
BID regulation by p53 contributes to chemosensitivity
JK Sax et al.
NATURE CELL BIOLOGY (2002)
CD40, an extracellular receptor for binding and uptake of Hsp70-peptide complexes
T Becker et al.
JOURNAL OF CELL BIOLOGY (2002)
Involvement of LOX-1 in dendritic cell-mediated antigen cross-presentation
Y Delneste et al.
IMMUNITY (2002)
Hsp72 and stress kinase c-jun N-terminal kinase regulate the bid-dependent pathway in tumor necrosis factor-induced apoptosis
VL Gabai et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Novel signal transduction pathway utilized by extracellular HSP70 -: Role of Toll-like receptor (TLR) 2 AND TLR4
A Asea et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
HSP70 as endogenous stimulus of the toll/interleukin-1 receptor signal pathway
RM Vabulas et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Serum cytokine concentrations in patients with cervical cancer:: Interleukin-4, interferon-γ, and monocyte chemoattractant protein-1
A Lebrecht et al.
GYNECOLOGIC ONCOLOGY (2001)
From the cradle to the grave:: molecular chaperones that may choose between folding and degradation
J Höhfeld et al.
EMBO REPORTS (2001)
Heat-shock protein 70 antagonizes apoptosis-inducing factor
L Ravagnan et al.
NATURE CELL BIOLOGY (2001)
CD91 is a common receptor for heat shock proteins gp96, hsp90, hsp70, and calreticulin
S Basu et al.
IMMUNITY (2001)
The ATPase domain of hsp70 possesses a unique binding specificity for 3′-sulfogalactolipids
D Mamelak et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Stress management - heat shock protein-70 and the regulation of apoptosis
HM Beere et al.
TRENDS IN CELL BIOLOGY (2001)
The Hsc70 co-chaperone CHIP targets immature CFTR for proteasomal degradation
GC Meacham et al.
NATURE CELL BIOLOGY (2001)
The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins
P Connell et al.
NATURE CELL BIOLOGY (2001)
Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome
HM Beere et al.
NATURE CELL BIOLOGY (2000)
Selective depletion of heat shock protein 70 (Hsp70) activates a tumor-specific death program that is independent of caspases and bypasses Bcl-2
J Nylandsted et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Structure of TPR domain-peptide complexes: Critical elements in the assembly of the Hsp70-Hsp90 multichaperone machine
C Scheufler et al.
CELL (2000)
Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway
C Tournier et al.
SCIENCE (2000)
HSP70 stimulates cytokine production through a CD14-dependant pathway, demonstrating its dual role as a chaperone and cytokine
A Asea et al.
NATURE MEDICINE (2000)
Structure and dimerization of a soluble form of B7-1
S Ikemizu et al.
IMMUNITY (2000)
分享论文
