相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Fibroblast Primary Cilia Are Required for Cardiac Fibrosis
Elisa Villalobos et al.
CIRCULATION (2019)
Unique and overlapping GLI1 and GLI2 transcriptional targets in neoplastic chondrocytes
Shabana Amanda Ali et al.
PLOS ONE (2019)
Secreted metalloproteases ADAMTS9 and ADAMTS20 have a non-canonical role in ciliary vesicle growth during ciliogenesis
Sumeda Nandadasa et al.
NATURE COMMUNICATIONS (2019)
IFT20 is required for the maintenance of cartilaginous matrix in condylar cartilage
Megumi Kitami et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2019)
Gene correlation network analysis to identify regulatory factors in idiopathic pulmonary fibrosis
John E. McDonough et al.
THORAX (2019)
Hypomorphic mutations of TRIP11 cause odontochondrodysplasia
Anika Wehrle et al.
JCI INSIGHT (2019)
Mechanism and dynamics of INPP5E transport into and inside the ciliary compartment
Stefanie Kristine Koesling et al.
BIOLOGICAL CHEMISTRY (2018)
Runx2, an inducer of osteoblast and chondrocyte differentiation
Toshihisa Komori
HISTOCHEMISTRY AND CELL BIOLOGY (2018)
Mechanical loading induces primary cilia disassembly in tendon cells via TGFβ and HDAC6
Daniel T. Rowson et al.
SCIENTIFIC REPORTS (2018)
Osteoarthritis-Like Changes in Bardet-Biedl Syndrome Mutant Ciliopathy Mice (Bbs1M390R/M390R): Evidence for a Role of Primary Cilia in Cartilage Homeostasis and Regulation of Inflammation
Isaac D. Sheffield et al.
FRONTIERS IN PHYSIOLOGY (2018)
PIP5 Kinases Regulate Membrane Phosphoinositide and Actin Composition for Targeted Granule Secretion by Cytotoxic Lymphocytes
Christian M. Gawden-Bone et al.
IMMUNITY (2018)
Primary Cilia and Mammalian Hedgehog Signaling
Fiona Bangs et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2017)
Planar cell polarity in development and disease
Mitchell T. Butler et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2017)
KIF13B establishes a CAV1-enriched microdomain at the ciliary transition zone to promote Sonic hedgehog signalling
Kenneth B. Schou et al.
NATURE COMMUNICATIONS (2017)
Inhibition of Shedding of Low-Density Lipoprotein Receptor-Related Protein 1 Reverses Cartilage Matrix Degradation in Osteoarthritis
Kazuhiro Yamamoto et al.
ARTHRITIS & RHEUMATOLOGY (2017)
A tectorin-based matrix and planar cell polarity genes are required for normal collagen-fibril orientation in the developing tectorial membrane
Richard J. Goodyear et al.
DEVELOPMENT (2017)
Routes and machinery of primary cilium biogenesis
Miguel Bernabe-Rubio et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2017)
A Role for Primary Cilia in Aortic Valve Development and Disease
Katelynn A. Toomer et al.
DEVELOPMENTAL DYNAMICS (2017)
Ciliary Hedgehog Signaling Restricts Injury-Induced Adipogenesis
Daniel Kopinke et al.
CELL (2017)
Regulation of Cholesterol Homeostasis by Hedgehog Signaling in Osteoarthritic Cartilage
Shabana Amanda Ali et al.
ARTHRITIS & RHEUMATOLOGY (2016)
Endothelial primary cilia inhibit atherosclerosis
Colin Dinsmore et al.
EMBO REPORTS (2016)
Hedgehog inhibits β-catenin activity in synovial joint development and osteoarthritis
Jason S. Rockel et al.
JOURNAL OF CLINICAL INVESTIGATION (2016)
Zonal variation in primary cilia elongation correlates with localized biomechanical degradation in stress deprived tendon
Daniel Rowson et al.
JOURNAL OF ORTHOPAEDIC RESEARCH (2016)
MMP-13 is constitutively produced in human chondrocytes and co-endocytosed with ADAMTS-5 and TIMP-3 by the endocytic receptor LRP1
Kazuhiro Yamamoto et al.
MATRIX BIOLOGY (2016)
Canonical and noncanonical intraflagellar transport regulates craniofacial skeletal development
Kazuo Noda et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
A mutation in VPS15 (PIK3R4) causes a ciliopathy and affects IFT20 release from the cis-Golgi
Corinne Stoetzel et al.
NATURE COMMUNICATIONS (2016)
Endocytic recycling protein EHD1 regulates primary cilia morphogenesis and SHH signaling during neural tube development
Sohinee Bhattacharyya et al.
SCIENTIFIC REPORTS (2016)
The exocyst gene Sec10 regulates renal epithelial monolayer homeostasis and apoptotic sensitivity
Noemi Polgar et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2015)
The small GTPase Rab29 is a common regulator of immune synapse assembly and ciliogenesis
A. Onnis et al.
CELL DEATH AND DIFFERENTIATION (2015)
Mother Centriole Distal Appendages Mediate Centrosome Docking at the Immunological Synapse and Reveal Mechanistic Parallels with Ciliogenesis
Jane C. Stinchcombe et al.
CURRENT BIOLOGY (2015)
Proteomics of Primary Cilia by Proximity Labeling
David U. Mick et al.
DEVELOPMENTAL CELL (2015)
Modulation of Ciliary Phosphoinositide Content Regulates Trafficking and Sonic Hedgehog Signaling Output
Marcelo Chavez et al.
DEVELOPMENTAL CELL (2015)
Phosphoinositides Regulate Ciliary Protein Trafficking to Modulate Hedgehog Signaling
Francesc R. Garcia-Gonzalo et al.
DEVELOPMENTAL CELL (2015)
Global genetic analysis in mice unveils central role for cilia in congenital heart disease
You Li et al.
NATURE (2015)
Early steps in primary cilium assembly require EHD1/EHD3-dependent ciliary vesicle formation
Quanlong Lu et al.
NATURE CELL BIOLOGY (2015)
Interleukin-1 Acts via the JNK-2 Signaling Pathway to Induce Aggrecan Degradation by Human Chondrocytes
Heba M. Ismail et al.
ARTHRITIS & RHEUMATOLOGY (2015)
The growth plate's response to load is partially mediated by mechano-sensing via the chondrocytic primary cilium
Yoach Rais et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2015)
Deletion of IFT80 Impairs Epiphyseal and Articular Cartilage Formation Due to Disruption of Chondrocyte Differentiation
Xue Yuan et al.
PLOS ONE (2015)
Hedgehog signalling does not stimulate cartilage catabolism and is inhibited by Interleukin-1β
Clare L. Thompson et al.
ARTHRITIS RESEARCH & THERAPY (2015)
KIF13B enhances the endocytosis of LRP1 by recruiting LRP1 to caveolae
Yoshimitsu Kanai et al.
JOURNAL OF CELL BIOLOGY (2014)
Specific recycling receptors are targeted to the immune synapse by the intraflagellar transport system
Francesca Finetti et al.
JOURNAL OF CELL SCIENCE (2014)
The endocytic activity of the flagellar pocket in Trypanosoma brucei is regulated by an adjacent phosphatidylinositol phosphate kinase
Lars Demmel et al.
JOURNAL OF CELL SCIENCE (2014)
Remodelling the extracellular matrix in development and disease
Caroline Bonnans et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)
Primary cilia disassembly down-regulates mechanosensitive hedgehog signalling: a feedback mechanism controlling ADAMTS-5 expression in chondrocytes
C. L. Thompson et al.
OSTEOARTHRITIS AND CARTILAGE (2014)
Shear stress-dependent regulation of apical endocytosis in renal proximal tubule cells mediated by primary cilia
Venkatesan Raghavan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Disrupting the Indian hedgehog signaling pathway in vivo attenuates surgically induced osteoarthritis progression in Col2a1-CreER(T2); Ihh(fl)/(fl) mice
Jingming Zhou et al.
ARTHRITIS RESEARCH & THERAPY (2014)
LRP-1-mediated endocytosis regulates extracellular activity of ADAMTS-5 in articular cartilage
Kazuhiro Yamamoto et al.
FASEB JOURNAL (2013)
Centriole distal appendages promote membrane docking, leading to cilia initiation
Barbara E. Tanos et al.
GENES & DEVELOPMENT (2013)
Ift88 regulates Hedgehog signaling, Sfrp5 expression, and β-catenin activity in post-natal growth plate
Ching-Fang Chang et al.
JOURNAL OF ORTHOPAEDIC RESEARCH (2013)
Nonmuscle myosin II powered transport of newly formed collagen fibrils at the plasma membrane
Nicholas S. Kalson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
TGF-β Signaling Is Associated with Endocytosis at the Pocket Region of the Primary Cilium
Christian Alexandro Clement et al.
CELL REPORTS (2013)
Hedgehog signaling controls fibroblast activation and tissue fibrosis in systemic sclerosis
Angelika Horn et al.
ARTHRITIS AND RHEUMATISM (2012)
The extracellular matrix and ciliary signaling
Tamina Seeger-Nukpezah et al.
CURRENT OPINION IN CELL BIOLOGY (2012)
IFT25 Links the Signal-Dependent Movement of Hedgehog Components to Intraflagellar Transport
Brian T. Keady et al.
DEVELOPMENTAL CELL (2012)
Primary cilia as biomechanical sensors in regulating endothelial function
Anastasia D. Egorova et al.
DIFFERENTIATION (2012)
Primary cilia mediate mechanotransduction through control of ATP-induced Ca2+ signaling in compressed chondrocytes
Angus K. T. Wann et al.
FASEB JOURNAL (2012)
Scoring a backstage pass: Mechanisms of ciliogenesis and ciliary access
Francesc R. Garcia-Gonzalo et al.
JOURNAL OF CELL BIOLOGY (2012)
Depletion of primary cilia in articular chondrocytes results in reduced Gli3 repressor to activator ratio, increased Hedgehog signaling, and symptoms of early osteoarthritis
C. -F Chang et al.
OSTEOARTHRITIS AND CARTILAGE (2012)
Activation of Indian hedgehog promotes chondrocyte hypertrophy and upregulation of MMP-13 in human osteoarthritic cartilage
F. Wei et al.
OSTEOARTHRITIS AND CARTILAGE (2012)
Chondrocyte hypertrophy and osteoarthritis: role in initiation and progression of cartilage degeneration?
P. M. van der Kraan et al.
OSTEOARTHRITIS AND CARTILAGE (2012)
Orientation of Primary Cilia of Articular Chondrocytes in Three-Dimensional Space
Cornelia E. Farnum et al.
ANATOMICAL RECORD-ADVANCES IN INTEGRATIVE ANATOMY AND EVOLUTIONARY BIOLOGY (2011)
Fibrosis and progression of Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Jill Norman
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2011)
Strange as it may seem: the many links between Wnt signaling, planar cell polarity, and cilia
John B. Wallingford et al.
GENES & DEVELOPMENT (2011)
Regulating the transition from centriole to basal body
Tetsuo Kobayashi et al.
JOURNAL OF CELL BIOLOGY (2011)
Effect of localization, length and orientation of chondrocytic primary cilium on murine growth plate organization
Maria-Grazia Ascenzi et al.
JOURNAL OF THEORETICAL BIOLOGY (2011)
The cilia protein IFT88 is required for spindle orientation in mitosis
Benedicte Delaval et al.
NATURE CELL BIOLOGY (2011)
Regulation of mechanical stress-induced MMP-13 and ADAMTS-5 expression by RUNX-2 transcriptional factor in SW1353 chondrocyte-like cells
T. Tetsunaga et al.
OSTEOARTHRITIS AND CARTILAGE (2011)
Uric acid is a danger signal of increasing risk for osteoarthritis through inflammasome activation
Anna E. Denoble et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
The Exocyst Protein Sec10 Interacts with Polycystin-2 and Knockdown Causes PKD-Phenotypes
Ben Fogelgren et al.
PLOS GENETICS (2011)
Postnatal development of collagen structure in ovine articular cartilage
Mark C. van Turnhout et al.
BMC DEVELOPMENTAL BIOLOGY (2010)
Mechanical loading modulates chondrocyte primary cilia incidence and length
Susan R. McGlashan et al.
CELL BIOLOGY INTERNATIONAL (2010)
Characterization of TIMP-3 in human articular talar cartilage
Kirsten J. Morris et al.
CONNECTIVE TISSUE RESEARCH (2010)
The ADPKD genes pkd1a/b and pkd2 regulate extracellular matrix formation
Steve Mangos et al.
DISEASE MODELS & MECHANISMS (2010)
The ciliary pocket: an endocytic membrane domain at the base of primary and motile cilia
Anahi Molla-Herman et al.
JOURNAL OF CELL SCIENCE (2010)
Primary Cilia Are Highly Oriented with Respect to Collagen Direction and Long Axis of Extensor Tendon
Eve Donnelly et al.
JOURNAL OF ORTHOPAEDIC RESEARCH (2010)
Primary cilia organization reflects polarity in the growth plate and implies loss of polarity and mosaicism in osteochondroma
Carlos E. de Andrea et al.
LABORATORY INVESTIGATION (2010)
Lethal Skeletal Dysplasia in Mice and Humans Lacking the Golgin GMAP-210
Patrick Smits et al.
NEW ENGLAND JOURNAL OF MEDICINE (2010)
Maturation of collagen fibril network structure in tibial and femoral cartilage of rabbits
P. Julkunen et al.
OSTEOARTHRITIS AND CARTILAGE (2010)
Coordination of Rab8 and Rab11 in primary ciliogenesis
Andreas Knoedler et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Actin and endocytosis: mechanisms and phylogeny
Brian J. Galletta et al.
CURRENT OPINION IN CELL BIOLOGY (2009)
The nonmotile ciliopathies
Jonathan L. Tobin et al.
GENETICS IN MEDICINE (2009)
Toxic tubular injury in kidneys from Pkd1-deletion mice accelerates cystogenesis accompanied by dysregulated planar cell polarity and canonical Wnt signaling pathways
Hester Happe et al.
HUMAN MOLECULAR GENETICS (2009)
Cartilage Abnormalities Associated with Defects of Chondrocytic Primary Cilia in Bardet-Biedl Syndrome Mutant Mice
Anjan P. Kaushik et al.
JOURNAL OF ORTHOPAEDIC RESEARCH (2009)
The Exocyst Protein Sec10 Is Necessary for Primary Ciliogenesis and Cystogenesis In Vitro
Xiaofeng Zuo et al.
MOLECULAR BIOLOGY OF THE CELL (2009)
Intraflagellar transport is required for polarized recycling of the TCR/CD3 complex to the immune synapse
Francesca Finetti et al.
NATURE CELL BIOLOGY (2009)
Modulating hedgehog signaling can attenuate the severity of osteoarthritis
Alvin C. Lin et al.
NATURE MEDICINE (2009)
The trypanosome flagellar pocket
Mark C. Field et al.
NATURE REVIEWS MICROBIOLOGY (2009)
Changes in spatial collagen content and collagen network architecture in porcine articular cartilage during growth and maturation
J. Rieppo et al.
OSTEOARTHRITIS AND CARTILAGE (2009)
Endothelial primary cilia in areas of disturbed flow are at the base of atherosclerosis
Kim Van der Heiden et al.
ATHEROSCLEROSIS (2008)
Endothelial cilia are fluid shear sensors that regulate calcium signaling and nitric oxide production through polycystin-1
Surya M. Nauli et al.
CIRCULATION (2008)
Primary cilia in osteoarthritic chondrocytes: From chondrons to clusters
S. R. McGlashan et al.
DEVELOPMENTAL DYNAMICS (2008)
The Oak Ridge Polycystic Kidney mouse: Modeling ciliopathies of mice and men
Jonathan M. Lehman et al.
DEVELOPMENTAL DYNAMICS (2008)
Role of cartilage collagen fibrils networks in knee joint biomechanics under compression
R. Shirazi et al.
JOURNAL OF BIOMECHANICS (2008)
Deletion of IFT20 in the mouse kidney causes misorientation of the mitotic spindle and cystic kidney disease
Julie A. Jonassen et al.
JOURNAL OF CELL BIOLOGY (2008)
Tension is required for fibripositor formation
Zoher Kapacce et al.
MATRIX BIOLOGY (2008)
The Golgin GMAP210/TRIP11 Anchors IFT20 to the Golgi Complex
John A. Follit et al.
PLOS GENETICS (2008)
Loss of apical monocilia on collecting duct principal cells impairs ATP secretion across the apical cell surface and ATP-dependent and flow-induced calcium signals
Michael B. Hovater et al.
PURINERGIC SIGNALLING (2008)
Ciliary proteins link basal body polarization to planar cell polarity regulation
Chonnettia Jones et al.
NATURE GENETICS (2008)
Characterization of the human ADAMTS-5 (aggrecanase-2) gene promoter
Kannan Thirunavukkarasu et al.
MOLECULAR BIOLOGY REPORTS (2007)
Expression of ADAMTS4 (aggrecanase-1) in human osteoarthritic cartilage
Satoko Naito et al.
PATHOLOGY INTERNATIONAL (2007)
Tendon development requires regulation of cell condensation and cell shape via cadherin-11-mediated cell-cell junctions
Susan H. Richardson et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
Patched1 regulates Hedgehog signaling at the primary cilium
Rajat Rohatgi et al.
SCIENCE (2007)
Ihh/Gli2 signaling promotes regulating Runx2 expression osteoblast differentiation by and function
Atsuko Shimoyama et al.
MOLECULAR BIOLOGY OF THE CELL (2007)
Proteolytic activities of human ADAMTS-5 - Comparative studies with ADAMTS-4
Christi Gendron et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Development of the post-natal growth plate requires intraflagellar transport proteins
Buer Song et al.
DEVELOPMENTAL BIOLOGY (2007)
Articular cartilage and growth plate defects are associated with chondrocyte cytoskeletal abnormalities in Tg737orpk mice lacking the primary cilia protein polaris
S. R. McGlashan et al.
MATRIX BIOLOGY (2007)
Increased collagen and aggrecan degradation with age in the joints of Timp3-/- mice
Solmaz Sahebjam et al.
ARTHRITIS AND RHEUMATISM (2007)
Intraflagellar transport is essential for endochondral bone formation
Courtney J. Haycraft et al.
DEVELOPMENT (2007)
Actin filaments are required for fibripositor-mediated collagen fibril alignment in tendon
Elizabeth G. Canty et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Purinergic pathway suppresses the release of NO and stimulates proteoglycan synthesis in chondrocyte/agarose constructs subjected to dynamic compression
T. T. Chowdhury et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2006)
Localization of extracellular matrix receptors on the chondrocyte primary cilium
Susan R. McGlashan et al.
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2006)
The intraflagellar transport protein IFT20 is associated with the Golgi complex and is required for cilia assembly
John A. Follit et al.
MOLECULAR BIOLOGY OF THE CELL (2006)
Contribution of runt-related transcription factor 2 to the pathogenesis of osteoarthritis in mice after induction of knee joint instability
Satoru Kamekura et al.
ARTHRITIS AND RHEUMATISM (2006)
Haploinsufficiency of Pkd2 is associated with increased tubular cell proliferation and interstitial fibrosis in two murine Pkd2 models
Ming Yang Chang et al.
NEPHROLOGY DIALYSIS TRANSPLANTATION (2006)
A pericellular collagenase directs the 3-dimensional development of white adipose tissue
Tae-Hwa Chun et al.
CELL (2006)
Ciliogenesis defects in embryos lacking inturned or fuzzy function are associated with failure of planar cell polarity and Hedgehog signaling
TJ Park et al.
NATURE GENETICS (2006)
Mechanoregulation of intracellular Ca2+ concentration is attenuated in collecting duct of monocilium-impaired orpk mice
W Liu et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2005)
Vertebrate Smoothened functions at the primary cilium
KC Corbit et al.
NATURE (2005)
Expression of polycystin-1 enhances endoplasmic reticulum calcium uptake and decreases capacitative calcium entry in ATP-stimulated MDCK cells
KM Hooper et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2005)
Indian hedgehog stimulates periarticular chondrocyte differentiation to regulate growth plate length independently of PTHrP
T Kobayashi et al.
JOURNAL OF CLINICAL INVESTIGATION (2005)
Activation-induced polarized recycling targets T cell antigen receptors to the immunological synapse: Involvement of SNARE complexes
V Das et al.
IMMUNITY (2004)
Expression profiling of metalloproteinases and their inhibitors in cartilage
L Kevorkian et al.
ARTHRITIS AND RHEUMATISM (2004)
Coalignment of plasma membrane channels and protrusions (fibripositors) specifies the parallelism of tendon
EG Canty et al.
JOURNAL OF CELL BIOLOGY (2004)
Ultrastructural, tomographic and confocal imaging of the chondrocyte primary cilium in situ
CG Jensen et al.
CELL BIOLOGY INTERNATIONAL (2004)
TIMP-3 inhibits aggrecanase-mediated glycosaminoglycan release from cartilage explants stimulated by catabolic factors
C Gendron et al.
FEBS LETTERS (2003)
Hedgehog signalling in the mouse requires intraflagellar transport proteins
DW Huangfu et al.
NATURE (2003)
Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells
SM Nauli et al.
NATURE GENETICS (2003)
Intraflagellar transport
JL Rosenbaum et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2002)
Importance of the superficial tissue layer for the indentation stiffness of articular cartilage
RK Korhonen et al.
MEDICAL ENGINEERING & PHYSICS (2002)
Bending the MDCK cell primary cilium increases intracellular calcium
HA Praetorius et al.
JOURNAL OF MEMBRANE BIOLOGY (2001)
Indian hedgehog is an essential component of mechanotransduction complex to stimulate chondrocyte proliferation
QQ Wu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Mechanical loading regulates protease production by fibroblasts in three-dimensional collagen substrates
RT Prajapati et al.
WOUND REPAIR AND REGENERATION (2000)