相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Alternative Splicing of ALS Genes: Misregulation and Potential Therapies
Benedetta Perrone et al.
CELLULAR AND MOLECULAR NEUROBIOLOGY (2020)
Oncogenic Y-box binding protein-1 as an effective therapeutic target in drug-resistant cancer
Michihiko Kuwano et al.
CANCER SCIENCE (2019)
Targeting RNA: A Transformative Therapeutic Strategy
Wei Yin et al.
CTS-CLINICAL AND TRANSLATIONAL SCIENCE (2019)
Reactivation of nonsense-mediated mRNA decay protects against C9orf72 dipeptide-repeat neurotoxicity
Wangchao Xu et al.
BRAIN (2019)
Disruption of RNA Metabolism in Neurological Diseases and Emerging Therapeutic Interventions
Julia K. Nussbacher et al.
NEURON (2019)
NetworkAnalyst 3.0: a visual analytics platform for comprehensive gene expression profiling and meta-analysis
Guangyan Zhou et al.
NUCLEIC ACIDS RESEARCH (2019)
Integrative multi-omic analysis identifies new drivers and pathways in molecularly distinct subtypes of ALS
Giovanna Morello et al.
SCIENTIFIC REPORTS (2019)
YB-1 recruitment to stress granules in zebrafish cells reveals a differential adaptive response to stress
Andrea Maria Guarino et al.
SCIENTIFIC REPORTS (2019)
Alternative Splicing Regulatory Networks: Functions, Mechanisms, and Evolution
Jernej Ule et al.
MOLECULAR CELL (2019)
Postmortem Cortex Samples Identify Distinct Molecular Subtypes of ALS: Retrotransposon Activation, Oxidative Stress, and Activated Glia
Oliver H. Tam et al.
CELL REPORTS (2019)
Key role of SMN/SYNCRIP and RNA-Motif 7 in spinal muscular atrophy: RNA-Seq and motif analysis of human motor neurons
Federica Rizzo et al.
BRAIN (2019)
RNA Dysregulation in Amyotrophic Lateral Sclerosis
Zoe Butti et al.
FRONTIERS IN GENETICS (2019)
Copy Number Variations in Amyotrophic Lateral Sclerosis: Piecing the Mosaic Tiles Together through a Systems Biology Approach
Giovanna Morello et al.
MOLECULAR NEUROBIOLOGY (2018)
The DifferentialNet database of differential protein-protein interactions in human tissues
Omer Basha et al.
NUCLEIC ACIDS RESEARCH (2018)
Regulation of alternative mRNA splicing: old players and new perspectives
Heidi Dvinge
FEBS LETTERS (2018)
Network strategy to investigate differential pathways in sporadic amyotrophic lateral sclerosis
Li-Hong Han et al.
JOURNAL OF CANCER RESEARCH AND THERAPEUTICS (2018)
Neuron-specific alternative splicing of transcriptional machineries: Implications for neurodevelopmental disorders
Robert S. Porter et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2018)
Whole blood transcriptome analysis in amyotrophic lateral sclerosis: A biomarker study
Wouter van Rheenen et al.
PLOS ONE (2018)
Minor spliceosome and disease
Bhupendra Verma et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2018)
Precise temporal regulation of alternative splicing during neural development
Sebastien M. Weyn-Vanhentenryck et al.
NATURE COMMUNICATIONS (2018)
Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins
Binkai Chi et al.
SCIENTIFIC REPORTS (2018)
C9orf72-mediated ALS and FTD: multiple pathways to disease
Rubika Balendra et al.
NATURE REVIEWS NEUROLOGY (2018)
A Systems-Level Study Reveals Regulators of Membrane-less Organelles in Human Cells
Doris Berchtold et al.
MOLECULAR CELL (2018)
ALS mutations of FUS suppress protein translation and disrupt the regulation of nonsense-mediated decay
Marisa Kamelgarn et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Y-box binding protein YBX1 and its correlated genes as biomarkers for poor outcomes in patients with breast cancer
Tomohiro Shibata et al.
Oncotarget (2018)
Axon-Seq Decodes the Motor Axon Transcriptome and Its Modulation in Response to ALS
Jik Nijssen et al.
STEM CELL REPORTS (2018)
The emerging role of minor intron splicing in neurological disorders
Daniel Jutzi et al.
CELL STRESS (2018)
Alternative Splicing in Neurogenesis and Brain Development
Chun-Hao Su et al.
FRONTIERS IN MOLECULAR BIOSCIENCES (2018)
Artificial intelligence in neurodegenerative disease research: use of IBM Watson to identify additional RNA-binding proteins altered in amyotrophic lateral sclerosis
Nadine Bakkar et al.
ACTA NEUROPATHOLOGICA (2018)
Splicing factors act as genetic modulators of TDP-43 production in a new autoregulatory TDP-43 Drosophila model
Marine Pons et al.
HUMAN MOLECULAR GENETICS (2017)
Selection and Prioritization of Candidate Drug Targets for Amyotrophic Lateral Sclerosis Through a Meta-Analysis Approach
Giovanna Morello et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2017)
SRSF1-dependent nuclear export inhibition of C9ORF72 repeat transcripts prevents neurodegeneration and associated motor deficits
Guillaume M. Hautbergue et al.
NATURE COMMUNICATIONS (2017)
Single-Cell Analysis of SMN Reveals Its Broader Role in Neuromuscular Disease
Natalia Rodriguez-Muela et al.
CELL REPORTS (2017)
Post-transcriptional Inhibition of Hsc70-4/HSPA8 Expression Leads to Synaptic Vesicle Cycling Defects in Multiple Models of ALS
Alyssa N. Coyne et al.
CELL REPORTS (2017)
Evidence that C9ORF72 Dipeptide Repeat Proteins Associate with U2 snRNP to Cause Mis-splicing in ALS/FTD Patients
Shanye Yin et al.
CELL REPORTS (2017)
Cellular Chaperones As Therapeutic Targets in ALS to Restore Protein Homeostasis and Improve Cellular Function.
Bernadett Kalmar et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2017)
Molecular taxonomy of sporadic amyotrophic Lateral sclerosis Using disease-associated Genes
Giovanna Morello et al.
FRONTIERS IN NEUROLOGY (2017)
The spliceosome-associated protein Mfap1 binds to VCP in Drosophila
Sandra Rode et al.
PLOS ONE (2017)
U6 snRNA expression prevents toxicity in TDP-43-knockdown cells
Masao Yahara et al.
PLOS ONE (2017)
ALS Associated Mutations in Matrin 3 Alter Protein-Protein Interactions and Impede mRNA Nuclear Export
Ashley Boehringer et al.
SCIENTIFIC REPORTS (2017)
Nanoscale Analysis Reveals the Maturation of Neurodegeneration-Associated Protein Aggregates: Grown in mRNA Granules then Released by Stress Granule Proteins
Sanae Abrakhi et al.
ACS NANO (2017)
The exon junction complex as a node of post-transcriptional networks
Herve Le Hir et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2016)
Minor intron splicing is regulated by FUS and affected by ALS-associated FUS mutants
Stefan Reber et al.
EMBO JOURNAL (2016)
FET proteins regulate lifespan and neuronal integrity
Martine Therrien et al.
SCIENTIFIC REPORTS (2016)
TDP-43 aggregation mirrors TDP-43 knockdown, affecting the expression levels of a common set of proteins
S. Prpar Mihevc et al.
SCIENTIFIC REPORTS (2016)
RNA splicing factors as oncoproteins and tumour suppressors
Heidi Dvinge et al.
NATURE REVIEWS CANCER (2016)
Mechanisms and Regulation of Alternative Pre-mRNA Splicing
Yeon Lee et al.
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 84 (2015)
InteractiVenn: a web-based tool for the analysis of sets through Venn diagrams
Henry Heberle et al.
BMC BIOINFORMATICS (2015)
Selection of Potential Pharmacological Targets in ALS Based on Whole-Genome Expression Profiling
Giovanna Morello et al.
CURRENT MEDICINAL CHEMISTRY (2015)
Transcriptional analysis reveals distinct subtypes in amyotrophic lateral sclerosis: implications for personalized therapy
Giovanna Morello et al.
FUTURE MEDICINAL CHEMISTRY (2015)
The architecture of the spliceosomal U4/U6.U5 tri-snRNP
Thi Hoang Duong Nguyen et al.
NATURE (2015)
Molecular classification of amyotrophic lateral sclerosis by unsupervised clustering of gene expression in motor cortex
Eleonora Aronica et al.
NEUROBIOLOGY OF DISEASE (2015)
Splicing: is there an alternative contribution to Parkinson's disease?
Valentina La Cognata et al.
NEUROGENETICS (2015)
Alternative Splicing in the Mammalian Nervous System: Recent Insights into Mechanisms and Functional Roles
Bushra Raj et al.
NEURON (2015)
Gene expression signatures in motor neurone disease fibroblasts reveal dysregulation of metabolism, hypoxia-response and RNA processing functions
R. Raman et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2015)
Linking RNA Dysfunction and Neurodegeneration in Amyotrophic Lateral Sclerosis
Sami J. Barmada
NEUROTHERAPEUTICS (2015)
U1 snRNP is mislocalized in ALS patient fibroblasts bearing NLS mutations in FUS and is required for motor neuron outgrowth in zebrafish
Yong Yu et al.
NUCLEIC ACIDS RESEARCH (2015)
Amelioration of toxicity in neuronal models of amyotrophic lateral sclerosis by hUPF1
Sami J. Barmada et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
FUS functions in coupling transcription to splicing by mediating an interaction between RNAP II and U1 snRNP
Yong Yu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
ALS-causative mutations in FUS/TLS confer gain and loss of function by altered association with SMN and U1-snRNP
Shuying Sun et al.
NATURE COMMUNICATIONS (2015)
Preservation of forelimb function by UPF1 gene therapy in a rat model of TDP-43-induced motor paralysis
K. L. Jackson et al.
GENE THERAPY (2015)
Nuclear TDP-43 causes neuronal toxicity by escaping from the inhibitory regulation by hnRNPs
Hiroaki Suzuki et al.
HUMAN MOLECULAR GENETICS (2015)
Mechanism of alternative splicing and its regulation
Yan Wang et al.
BIOMEDICAL REPORTS (2015)
Increasing the Coding Potential of Genomes Through Alternative Splicing: The Case of PARK2 Gene
Valentina La Cognata et al.
CURRENT GENOMICS (2014)
Upregulation of SYF2 Is Associated With Neuronal Apoptosis Caused by Reactive Astrogliosis to Neuroinflammation
Wei Xu et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2014)
Therapeutic modulation of eIF2α phosphorylation rescues TDP-43 toxicity in amyotrophic lateral sclerosis disease models
Hyung-Jun Kim et al.
NATURE GENETICS (2014)
Construction and Analysis of the Protein-Protein Interaction Networks Based on Gene Expression Profiles of Parkinson's Disease
Hindol Rakshit et al.
PLOS ONE (2014)
HnRNP C, YB-1 and hnRNP L coordinately enhance skipping of human MUSK exon 10 to generate a Wnt-insensitive MuSK isoform
Farhana Nasrin et al.
SCIENTIFIC REPORTS (2014)
The Supraspliceosome - A Multi-Task Machine for Regulated Pre-mRNA Processing in the Cell Nucleus
Kinneret Shefer et al.
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL (2014)
Splicing and beyond: The many faces of the Prp19 complex
Sittinan Chanarat et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2013)
Regulation of splicing by SR proteins and SR protein-specific kinases
Zhihong Zhou et al.
CHROMOSOMA (2013)
Decreased number of Gemini of coiled bodies and U12 snRNA level in amyotrophic lateral sclerosis
Tomohiko Ishihara et al.
HUMAN MOLECULAR GENETICS (2013)
ALS-associated mutations in FUS disrupt the axonal distribution and function of SMN
Ewout J. N. Groen et al.
HUMAN MOLECULAR GENETICS (2013)
SpliceAid-F: a database of human splicing factors and their RNA-binding sites
Matteo Giulietti et al.
NUCLEIC ACIDS RESEARCH (2013)
The significant other: splicing by the minor spliceosome
Janne J. Turunen et al.
WILEY INTERDISCIPLINARY REVIEWS-RNA (2013)
FUS binds the CTD of RNA polymerase II and regulates its phosphorylation at Ser2
Jacob C. Schwartz et al.
GENES & DEVELOPMENT (2012)
Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs
Clotilde Lagier-Tourenne et al.
NATURE NEUROSCIENCE (2012)
The spliceosome: a flexible, reversible macromolecular machine
Aaron A. Hoskins et al.
TRENDS IN BIOCHEMICAL SCIENCES (2012)
FUS-SMN Protein Interactions Link the Motor Neuron Diseases ALS and SMA
Tomohiro Yamazaki et al.
CELL REPORTS (2012)
A functional variant in ZNF512B is associated with susceptibility to amyotrophic lateral sclerosis in Japanese
Aritoshi Iida et al.
HUMAN MOLECULAR GENETICS (2011)
Molecular Determinants and Genetic Modifiers of Aggregation and Toxicity for the ALS Disease Protein FUS/TLS
Zhihui Sun et al.
PLOS BIOLOGY (2011)
Global Analysis of TDP-43 Interacting Proteins Reveals Strong Association with RNA Splicing and Translation Machinery
Brian D. Freibaum et al.
JOURNAL OF PROTEOME RESEARCH (2010)
SRRM2, a Potential Blood Biomarker Revealing High Alternative Splicing in Parkinson's Disease
Lina A. Shehadeh et al.
PLOS ONE (2010)
The assembly of a spliceosomal small nuclear ribonucleoprotein particle
Snehal Bhikhu Patel et al.
NUCLEIC ACIDS RESEARCH (2008)
SMN protects cells against mutant SOD1 toxicity by increasing chaperone activity
Tie Zou et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
The importance of bottlenecks in protein networks: Correlation with gene essentiality and expression dynamics
Haiyuan Yu et al.
PLOS COMPUTATIONAL BIOLOGY (2007)
Functional coupling of RNAP II transcription to spliceosome assembly
R Das et al.
GENES & DEVELOPMENT (2006)
Native spliceosomes assemble with Pre-mRNA to form supraspliceosomes
M Azubel et al.
JOURNAL OF MOLECULAR BIOLOGY (2006)
分享论文
